SE430689B - Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner - Google Patents

Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner

Info

Publication number
SE430689B
SE430689B SE7610842A SE7610842A SE430689B SE 430689 B SE430689 B SE 430689B SE 7610842 A SE7610842 A SE 7610842A SE 7610842 A SE7610842 A SE 7610842A SE 430689 B SE430689 B SE 430689B
Authority
SE
Sweden
Prior art keywords
tioamines
thiocarbamides
carbamides
guanidines
heterocyclic
Prior art date
Application number
SE7610842A
Other languages
English (en)
Swedish (sv)
Other versions
SE7610842L (sv
Inventor
G J Durant
J C Emmett
C R Ganellin
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26240626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE430689(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB635271A external-priority patent/GB1338169A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of SE7610842L publication Critical patent/SE7610842L/xx
Publication of SE430689B publication Critical patent/SE430689B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
SE7610842A 1971-03-09 1976-09-30 Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner SE430689B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB635271A GB1338169A (en) 1971-03-09 1971-03-09 Ureas thioureas and guanidines
GB3433471 1971-07-22

Publications (2)

Publication Number Publication Date
SE7610842L SE7610842L (sv) 1976-09-30
SE430689B true SE430689B (sv) 1983-12-05

Family

ID=26240626

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7202933A SE402288B (sv) 1971-03-09 1972-03-08 Forfarande for framstellning av foreningar vilka er antagonister mot vissa verkningar av histamin
SE7412680A SE410103B (sv) 1971-03-09 1974-10-09 Forfarande for framstellning av foreningar, vilka er antagonister mot vissa verkningar av histamin
SE7610842A SE430689B (sv) 1971-03-09 1976-09-30 Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7202933A SE402288B (sv) 1971-03-09 1972-03-08 Forfarande for framstellning av foreningar vilka er antagonister mot vissa verkningar av histamin
SE7412680A SE410103B (sv) 1971-03-09 1974-10-09 Forfarande for framstellning av foreningar, vilka er antagonister mot vissa verkningar av histamin

Country Status (21)

Country Link
JP (5) JPS5324422B1 (xx)
AR (2) AR197080A1 (xx)
BE (1) BE779775A (xx)
CY (1) CY856A (xx)
DK (1) DK139870B (xx)
EG (1) EG10876A (xx)
ES (1) ES400587A1 (xx)
FI (1) FI60393C (xx)
HK (1) HK55176A (xx)
HU (1) HU164509B (xx)
IE (1) IE36050B1 (xx)
IL (1) IL38821A (xx)
IT (1) IT1041101B (xx)
KE (1) KE2625A (xx)
MY (1) MY7600228A (xx)
NO (1) NO133196C (xx)
PH (2) PH12207A (xx)
SE (3) SE402288B (xx)
SG (1) SG28576G (xx)
SU (1) SU460628A3 (xx)
ZM (1) ZM3672A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
US4000296A (en) * 1972-09-05 1976-12-28 Smith Kline & French Laboratories Limited Imidazole alkylguanidine compounds
GB1398426A (en) * 1972-09-05 1975-06-18 Smith Kline French Lab Heterocyclic substituted guanidines
US4072748A (en) * 1972-09-05 1978-02-07 Smith Kline & French Laboratories Limited Certain guanidine compounds, and their use as inhibitors of histamine activity
US4129657A (en) 1975-03-21 1978-12-12 Smith, Kline & French Laboratories Limited Imidazole guanidines and use as inhibitors of histamine activity
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
JPH07107054B2 (ja) * 1987-05-20 1995-11-15 株式会社日本触媒 ４−メチル−５−〔（２−アミノエチル）チオメチル〕イミダゾ−ル二塩酸塩の製法
JP2933739B2 (ja) * 1990-04-09 1999-08-16 明治製菓株式会社 チアゾールまたはイミダゾール誘導体および抗潰瘍剤

Also Published As

Publication number Publication date
JPS53119869A (en) 1978-10-19
JPS5732063B2 (xx) 1982-07-08
NO133196B (xx) 1975-12-15
IT1041101B (it) 1980-01-10
EG10876A (en) 1976-07-31
IE36050L (en) 1972-09-09
IE36050B1 (en) 1976-08-04
SE402288B (sv) 1978-06-26
SU460628A3 (ru) 1975-02-15
JPS5459275A (en) 1979-05-12
FI60393B (fi) 1981-09-30
IL38821A0 (en) 1972-10-29
CY856A (en) 1976-09-10
SE410103B (sv) 1979-09-24
DK139870C (xx) 1979-10-08
JPS5811948B2 (ja) 1983-03-05
DK139870B (da) 1979-05-07
FI60393C (fi) 1982-01-11
JPS53119868A (en) 1978-10-19
AR197093A1 (es) 1974-03-15
PH12247A (en) 1978-12-12
HK55176A (en) 1976-09-17
IL38821A (en) 1975-05-22
JPS53119867A (en) 1978-10-19
MY7600228A (en) 1976-12-31
NO133196C (xx) 1976-03-24
KE2625A (en) 1976-05-28
PH12207A (en) 1978-11-29
JPS5324422B1 (xx) 1978-07-20
HU164509B (xx) 1974-02-28
JPS5742068B2 (xx) 1982-09-07
ES400587A1 (es) 1975-07-16
SG28576G (en) 1987-04-03
BE779775A (fr) 1972-08-24
AR197080A1 (es) 1974-03-15
SE7610842L (sv) 1976-09-30
ZM3672A1 (en) 1972-10-23
SE7412680L (xx) 1974-10-09

Similar Documents

Publication Publication Date Title
FI55379C (fi) Polyolefinmassa med baettre vattenavledningsegenskaper foer framstaellning av papper och massans framstaellningsfoerfarande
SE392269B (sv) Forfarande for framstellning av vissa indanyloxitetrazoler
FI55869B (fi) Foerfarande foer oxidering av en metallsulfid med salpetersyra
SE400292B (sv) Forfarande for framstellning av benshydryl-3-karbamoyloximetyl-7-tienylacetamido-7-metoxidecefalosporanat
SE384501B (sv) Forfarande for framstellning av d,d'-2,2'-(etylendiimino)-di-1-butanol-dihydroklorid
NO137385C (no) Fremgangsm}te for fremstilling av urea
SE430689B (sv) Heterocykliska tioaminer for framstellning av karbamider, tiokarbamider och guanidiner
FI54592B (fi) Foerpackning av straengar av med adhesionsmedel belagda glasfibrer och foerfarande foer framstaellning av foerpackningen
SE417200B (sv) Forfarande for framstellning av 2-nitro-5-imidazolaldehydderivat
SE405478B (sv) Forfarande for framstellning av alfa-sulfoacylcefalosporiner
SE406587B (sv) Forfarande for framstellning av 4-hydroximetyl-1-keto-1,2-dihydroftalazin
SE7505279L (sv) Forfarande for framstellning av hydroxipyrimidiner.
SE386175B (sv) Forfarande for framstellning av 1,4-bis-acylpiperaziner
SE399557B (sv) Forfarande for framstellning av tiantren-, tioxanten- och fenoxatiinderivat
SE394677B (sv) Forfarande for framstellning av 4-hydroxi-2h-1-bensotiopyran-3-karboxanilid-1,1-dioxider
TR17780A (tr) Mensucat techiz maddelerinin imaline mahsus usul
TR17956A (tr) 2,6-dinitroanilin herbisidler
SE390025B (sv) Forfarande for framstellning av 3 alfa-hydroxi-19-5 alfa-pregnan-11,20-dion
SE380520B (sv) Forfarande for framstellning av 1-cinnamylidenamino-3-bensylidenaminoguanidin
SE386897B (sv) Forfarande for framstellning av n-acyl-(piperazinoetyl)-pyrazoler
SE392902B (sv) Forfarande for framstellning av fenylimidazolidinoner
AR204501A1 (es) Procedimiento de preparacion de derivados de la tiazolin y benzotiazolin pirimidinona-5
SE387948B (sv) Forfarande for framstellning av tiofen
SE407061B (sv) Forfarande for framstellning av bensylpyrimidiner
IT966299B (it) Procedimento per la produzione di i, i diantrachinonili e relativi flavantroni

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7610842-2

Effective date: 19920408

Format of ref document f/p: F