IE35648L - Penicillins - Google Patents

Penicillins

Info

Publication number
IE35648L
IE35648L IE711178A IE117871A IE35648L IE 35648 L IE35648 L IE 35648L IE 711178 A IE711178 A IE 711178A IE 117871 A IE117871 A IE 117871A IE 35648 L IE35648 L IE 35648L
Authority
IE
Ireland
Prior art keywords
group
formula
acid
primary amino
alkyl group
Prior art date
Application number
IE711178A
Other versions
IE35648B1 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IE35648L publication Critical patent/IE35648L/en
Publication of IE35648B1 publication Critical patent/IE35648B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

A class of novel .beta.-amino penicillins of formula (IV) useful as antibacterial agents: (IV) and non-toxic salts and hydrolysable esters thereof, in which formula R is a C1 to C6 straight or branched chain alkyl group, a C5 to C7 cycloalkyl or cycloalkenyl group; R1 is hydrogen or a C1 to C6 alkyl group; or R and R1 taken together represent a C5 to C6 alkylene group which may be interrupted by a hetero atom. According to the process of preparation 6-aminopenicillanic acid or a salt or ester thereof or the reaction product of 6-aminopenicillanic acid with an organo silicon compound is treated with a reactive acylating derivative of an acid of the general formula (V) (V) wherein R and R1 are as defined in claim 1 and X is a nitrogen containing group which may be converted into a primary amino group, and subsequently converting the group X into a primary amino group. [CA1056817A]
IE1178/71A 1970-09-25 1971-09-17 Penicillins IE35648B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB4570470 1970-09-25
GB874371 1971-03-31
GB1599371 1971-05-20

Publications (2)

Publication Number Publication Date
IE35648L true IE35648L (en) 1972-03-25
IE35648B1 IE35648B1 (en) 1976-04-14

Family

ID=27255254

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1178/71A IE35648B1 (en) 1970-09-25 1971-09-17 Penicillins

Country Status (12)

Country Link
JP (1) JPS5622877B1 (en)
AT (1) AT309683B (en)
AU (1) AU464358B2 (en)
BE (1) BE773090A (en)
CA (1) CA1056817A (en)
CH (1) CH558809A (en)
DE (1) DE2147852A1 (en)
ES (1) ES395419A1 (en)
FR (1) FR2107980A1 (en)
IE (1) IE35648B1 (en)
IL (1) IL37762A0 (en)
NL (1) NL7112991A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190897B (en) * 1982-06-29 1988-02-24 Opos Biochimica Srl PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
IL68992A (en) * 1982-06-29 1991-06-10 Astra Laekemedel Ab Alpha-bromo diethyl carbonate and process for the preparation of ethoxycarbonyloxy esters of penicillanic acids
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
DE3641822A1 (en) * 1986-12-06 1988-06-16 Goedecke Ag USE OF DIHYDROPHENYLAMINOSAE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM FOR IMMUNULATION AND CYTOSTASE

Also Published As

Publication number Publication date
JPS5622877B1 (en) 1981-05-27
AU3386571A (en) 1973-03-29
ES395419A1 (en) 1974-09-16
CH558809A (en) 1975-02-14
IL37762A0 (en) 1971-11-29
FR2107980B1 (en) 1975-12-26
FR2107980A1 (en) 1972-05-12
DE2147852A1 (en) 1972-03-30
NL7112991A (en) 1972-03-28
AU464358B2 (en) 1975-08-21
CA1056817A (en) 1979-06-19
BE773090A (en) 1972-03-24
IE35648B1 (en) 1976-04-14
AT309683B (en) 1973-08-27

Similar Documents

Publication Publication Date Title
GB1405886A (en) Synergistic compositions comprising penicillin and cephalosporin antibiotics
GB1249425A (en) Acylated glucopyranoside derivatives
IE35648B1 (en) Penicillins
GB1201542A (en) alpha-AMINO-PENICILLIN PREPARATION BY A SILYL PROCESS
SE7506455L (en) ANTIBACTERIAL AGENTS
GB1314830A (en) Pharmaceutically useful benzomorphanes and their production
ES445489A1 (en) Antibiotic substances derived from antibiotic 67-694(rosamicin)and processes for their preparation
GB1501476A (en) Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives and a process for the preparation thereof
GB1347598A (en) Lincomycin derivatives and the manufacture thereof
IE35985B1 (en) 6-aminopenicillanic acid derivatives and a process for the manufacture thereof
GB1390754A (en) Penicillin and cephalosporin esters
GB876508A (en) Improvements in or relating to substances having antibiotic activity
GB1315630A (en) Penicillins
GB1302917A (en)
ES436198A1 (en) Substituted cephalosporin antibiotics
GB1470289A (en) Aminomethyl-arylmethylpenicillin derivatives
GB1315397A (en)
GB1217471A (en) A process for preparing organometallic aromatic silicon compounds
GB1383766A (en) Penicillins
KR790000338B1 (en) Process for preparation of penicillin derivatives
GB1333524A (en) Penicilloic acid derivatives
GB1495197A (en) Process for preparing pyridoxin derivatives
GB1476312A (en) Penicillins and cephalosporins
GB1398564A (en) 1-amino substituted-1-cycloalkane derivatives of 6-amino penicillanic acid
GB1259294A (en)