IE35643B1 - Bis-basic ketones of xanthene and xanthen-9-one and antiviral compositions thereof - Google Patents
Bis-basic ketones of xanthene and xanthen-9-one and antiviral compositions thereofInfo
- Publication number
- IE35643B1 IE35643B1 IE1168/71A IE116871A IE35643B1 IE 35643 B1 IE35643 B1 IE 35643B1 IE 1168/71 A IE1168/71 A IE 1168/71A IE 116871 A IE116871 A IE 116871A IE 35643 B1 IE35643 B1 IE 35643B1
- Authority
- IE
- Ireland
- Prior art keywords
- xanthene
- bis
- compounds
- alkyl
- xanthen
- Prior art date
Links
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 title abstract 5
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 title abstract 5
- JNELGWHKGNBSMD-UHFFFAOYSA-N xanthone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3OC2=C1 JNELGWHKGNBSMD-UHFFFAOYSA-N 0.000 title abstract 3
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000002576 ketones Chemical class 0.000 title 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- XJLAGWXLOUDILA-UHFFFAOYSA-N 4-[4-[7-(1,1-diethoxy-4-morpholin-4-ylbutyl)-9H-xanthen-2-yl]-4,4-diethoxybutyl]morpholine Chemical compound C(C)OC(CCCN1CCOCC1)(OCC)C1=CC=2CC3=CC(=CC=C3OC2C=C1)C(CCCN1CCOCC1)(OCC)OCC XJLAGWXLOUDILA-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 229910004373 HOAc Inorganic materials 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000005265 dialkylamine group Chemical group 0.000 abstract 1
- 125000005594 diketone group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
- 150000003732 xanthenes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Insertion, Bundling And Securing Of Wires For Electric Apparatuses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US097379A US3859286A (en) | 1970-12-11 | 1970-12-11 | Bis-basic ketones of xanthene and xanthen-9-one |
Publications (2)
Publication Number | Publication Date |
---|---|
IE35643L IE35643L (en) | 1972-06-11 |
IE35643B1 true IE35643B1 (en) | 1976-04-14 |
Family
ID=22263057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1168/71A IE35643B1 (en) | 1970-12-11 | 1971-09-15 | Bis-basic ketones of xanthene and xanthen-9-one and antiviral compositions thereof |
Country Status (21)
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4061768A (en) * | 1971-09-08 | 1977-12-06 | Burroughs Wellcome Co. | Certain cyclic carbonyl compounds used in the prophylaxis of allergic conditions |
US4108896A (en) * | 1972-12-21 | 1978-08-22 | Richardson-Merrell Inc. | Anthracene derivatives |
US4008240A (en) * | 1972-12-21 | 1977-02-15 | Richardson-Merrell Inc. | Xanthene and thioxanthene derivatives |
US3817992A (en) * | 1972-12-21 | 1974-06-18 | Richardson Merrell Inc | Xanthene and thioxanthene derivatives |
US4250097A (en) * | 1978-03-08 | 1981-02-10 | Syntex (U.S.A.) Inc. | Compositions for and a method of preventing diabetic complications |
DE3008411A1 (de) * | 1980-03-05 | 1981-09-10 | Merck Patent Gmbh, 6100 Darmstadt | Neue aromatisch-aliphatische ketone, ihre verwendung als photoinitiatoren sowie photopolymerisierbare systeme enthaltend solche ketone |
MXPA03006372A (es) * | 2001-01-16 | 2004-04-20 | Guilford Pharm Inc | Compuestos aromaticos simetricamente disustituidos y composiciones farmaceuticas para inhibir poli (adp-ribosa) glicohidrolasa y metodos para su uso. |
US10113075B2 (en) | 2014-09-04 | 2018-10-30 | Igm Malta Limited | Polycyclic photoinitiators |
JP7096817B2 (ja) * | 2016-11-04 | 2022-07-06 | オークランド ユニサービシーズ リミティド | 三環式複素環式誘導体及びその使用 |
AU2021242300B8 (en) * | 2020-03-26 | 2025-08-07 | Provectus Pharmatech, Inc. | Novel uses of halogenated xanthenes in oncology and virology |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA711333B (en) * | 1970-03-27 | 1971-11-24 | Richardson Merrell Inc | Bis-basic ketones of fluorene and fluorenone |
US3767674A (en) * | 1971-10-01 | 1973-10-23 | Ostra Lakemedel Ab | Cyclohexeno thioxanthones |
-
1970
- 1970-12-11 US US097379A patent/US3859286A/en not_active Expired - Lifetime
-
1971
- 1971-07-14 CA CA118,192A patent/CA948192A/en not_active Expired
- 1971-09-07 NO NO3324/71A patent/NO135249C/no unknown
- 1971-09-15 GB GB4302671A patent/GB1313454A/en not_active Expired
- 1971-09-15 IE IE1168/71A patent/IE35643B1/xx unknown
- 1971-09-17 IL IL37755A patent/IL37755A/xx unknown
- 1971-09-20 ZA ZA716267A patent/ZA716267B/xx unknown
- 1971-09-27 AU AU33908/71A patent/AU453068B2/en not_active Expired
- 1971-10-14 CH CH1501371A patent/CH562818A5/xx not_active IP Right Cessation
- 1971-10-18 DE DE19712151707 patent/DE2151707A1/de not_active Withdrawn
- 1971-10-20 JP JP8252971A patent/JPS5545549B1/ja active Pending
- 1971-11-05 AT AT1010272A patent/AT317890B/de not_active IP Right Cessation
- 1971-11-05 AT AT956871A patent/AT319944B/de not_active IP Right Cessation
- 1971-11-12 NL NL7115559A patent/NL7115559A/xx not_active Application Discontinuation
- 1971-11-19 CS CS8104A patent/CS166791B2/cs unknown
- 1971-12-03 SE SE7115518A patent/SE382458B/xx unknown
- 1971-12-06 AR AR239429A patent/AR196404A1/es active
- 1971-12-08 HU HURI458A patent/HU163026B/hu unknown
- 1971-12-10 BE BE776535A patent/BE776535A/xx unknown
- 1971-12-10 FR FR7144506A patent/FR2118031B1/fr not_active Expired
- 1971-12-10 DK DK605771A patent/DK132275C/da active
- 1971-12-10 ES ES397821A patent/ES397821A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES397821A1 (es) | 1975-06-16 |
HU163026B (enrdf_load_stackoverflow) | 1973-05-28 |
NL7115559A (enrdf_load_stackoverflow) | 1972-06-13 |
AR196404A1 (es) | 1973-12-27 |
DE2151707A1 (de) | 1972-06-29 |
CH562818A5 (enrdf_load_stackoverflow) | 1975-06-13 |
IE35643L (en) | 1972-06-11 |
SE382458B (sv) | 1976-02-02 |
NO135249C (enrdf_load_stackoverflow) | 1977-03-09 |
US3859286A (en) | 1975-01-07 |
JPS5545549B1 (enrdf_load_stackoverflow) | 1980-11-18 |
AT317890B (de) | 1974-09-25 |
DK132275B (da) | 1975-11-17 |
CA948192A (en) | 1974-05-28 |
FR2118031A1 (enrdf_load_stackoverflow) | 1972-07-28 |
NO135249B (enrdf_load_stackoverflow) | 1976-11-29 |
BE776535A (fr) | 1972-04-04 |
CS166791B2 (enrdf_load_stackoverflow) | 1976-03-29 |
IL37755A0 (en) | 1971-11-29 |
FR2118031B1 (enrdf_load_stackoverflow) | 1975-06-13 |
AT319944B (de) | 1975-01-10 |
AU3390871A (en) | 1973-04-05 |
IL37755A (en) | 1974-07-31 |
AU453068B2 (en) | 1974-09-19 |
ZA716267B (en) | 1972-05-31 |
GB1313454A (en) | 1973-04-11 |
DK132275C (da) | 1976-04-12 |
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