IE35369B1 - Tetrahydropyridine derivatives and a process for the manufacture thereof - Google Patents
Tetrahydropyridine derivatives and a process for the manufacture thereofInfo
- Publication number
- IE35369B1 IE35369B1 IE769/71A IE76971A IE35369B1 IE 35369 B1 IE35369 B1 IE 35369B1 IE 769/71 A IE769/71 A IE 769/71A IE 76971 A IE76971 A IE 76971A IE 35369 B1 IE35369 B1 IE 35369B1
- Authority
- IE
- Ireland
- Prior art keywords
- cycloalkyl
- alkyl
- compound
- compounds
- phenyltetrahydropyridine
- Prior art date
Links
- VSWICNJIUPRZIK-UHFFFAOYSA-N 2-piperideine Chemical class C1CNC=CC1 VSWICNJIUPRZIK-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 R<SP>2</SP> is H Chemical group 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- FAZSTBCWNTWANH-UHFFFAOYSA-N 1-phenyl-3,4-dihydro-2h-pyridine Chemical compound C1CCC=CN1C1=CC=CC=C1 FAZSTBCWNTWANH-UHFFFAOYSA-N 0.000 abstract 1
- BCHZICNRHXRCHY-UHFFFAOYSA-N 2h-oxazine Chemical compound N1OC=CC=C1 BCHZICNRHXRCHY-UHFFFAOYSA-N 0.000 abstract 1
- YFGQKSMNCPVFFG-UHFFFAOYSA-N 6-methyl-2h-1,3-oxazine Chemical compound CC1=CC=NCO1 YFGQKSMNCPVFFG-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- HDOWRFHMPULYOA-UHFFFAOYSA-N piperidin-4-ol Chemical compound OC1CCNCC1 HDOWRFHMPULYOA-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cleaning In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH931870A CH547802A (de) | 1970-06-19 | 1970-06-19 | Verfahren zur herstellung von tetrahydropyridinderivaten. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35369L IE35369L (en) | 1971-12-19 |
| IE35369B1 true IE35369B1 (en) | 1976-01-21 |
Family
ID=4350687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE769/71A IE35369B1 (en) | 1970-06-19 | 1971-06-15 | Tetrahydropyridine derivatives and a process for the manufacture thereof |
Country Status (16)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4985074A (enrdf_load_stackoverflow) * | 1972-12-22 | 1974-08-15 | ||
| US4320131A (en) * | 1981-03-16 | 1982-03-16 | Mead Johnson & Company | N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones |
| EP0885004B1 (en) * | 1996-03-08 | 2002-05-02 | F.Hoffmann-La Roche Ag | Use of 4-phenyl-3,6-dihydro-2h-pyridyl derivatives as nmda receptor subtype blockers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH506525A (de) * | 1968-12-24 | 1971-04-30 | Hoffmann La Roche | Verfahren zur Herstellung von aromatischen Äthern |
-
1970
- 1970-06-19 CH CH931870A patent/CH547802A/xx not_active IP Right Cessation
- 1970-06-22 NO NO2418/70A patent/NO133548C/no unknown
- 1970-06-23 DK DK323270A patent/DK132887C/da active
- 1970-06-24 SE SE7008767A patent/SE378814B/xx unknown
-
1971
- 1971-05-10 ZA ZA713032A patent/ZA713032B/xx unknown
- 1971-05-11 IL IL36827A patent/IL36827A/xx unknown
- 1971-06-09 DE DE19712128836 patent/DE2128836A1/de active Pending
- 1971-06-15 IE IE769/71A patent/IE35369B1/xx unknown
- 1971-06-16 GB GB4688472A patent/GB1338058A/en not_active Expired
- 1971-06-16 GB GB4688372A patent/GB1338057A/en not_active Expired
- 1971-06-16 GB GB4688572A patent/GB1338059A/en not_active Expired
- 1971-06-16 GB GB4688672A patent/GB1338060A/en not_active Expired
- 1971-06-16 GB GB2813671A patent/GB1338056A/en not_active Expired
- 1971-06-17 HU HUHO1386A patent/HU162417B/hu unknown
- 1971-06-18 AT AT776972A patent/AT309432B/de not_active IP Right Cessation
- 1971-06-18 AT AT777172A patent/AT311971B/de not_active IP Right Cessation
- 1971-06-18 NL NL7108416A patent/NL7108416A/xx unknown
- 1971-06-18 ES ES392388A patent/ES392388A1/es not_active Expired
- 1971-06-18 BE BE768689A patent/BE768689A/xx unknown
- 1971-06-18 CA CA116,015A patent/CA984844A/en not_active Expired
- 1971-06-18 AT AT529271A patent/AT309428B/de not_active IP Right Cessation
- 1971-06-18 AT AT776872A patent/AT309431B/de not_active IP Right Cessation
- 1971-06-18 FR FR7122334A patent/FR2100797B1/fr not_active Expired
- 1971-06-18 AT AT777072A patent/AT309433B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT309431B (de) | 1973-08-27 |
| NO133548C (enrdf_load_stackoverflow) | 1976-05-19 |
| IL36827A0 (en) | 1971-07-28 |
| DE2128836A1 (de) | 1971-12-23 |
| NO133548B (enrdf_load_stackoverflow) | 1976-02-09 |
| NL7108416A (enrdf_load_stackoverflow) | 1971-12-21 |
| AT309433B (de) | 1973-08-27 |
| DK132887C (da) | 1976-07-26 |
| CH547802A (de) | 1974-04-11 |
| IE35369L (en) | 1971-12-19 |
| ES392388A1 (es) | 1973-08-01 |
| AT311971B (de) | 1973-12-10 |
| BE768689A (fr) | 1971-12-20 |
| HU162417B (enrdf_load_stackoverflow) | 1973-02-28 |
| ZA713032B (en) | 1972-01-26 |
| FR2100797B1 (enrdf_load_stackoverflow) | 1974-08-23 |
| SE378814B (enrdf_load_stackoverflow) | 1975-09-15 |
| GB1338058A (en) | 1973-11-21 |
| AT309428B (de) | 1973-08-27 |
| GB1338060A (en) | 1973-11-21 |
| CA984844A (en) | 1976-03-02 |
| DK132887B (da) | 1976-02-23 |
| GB1338059A (en) | 1973-11-21 |
| IL36827A (en) | 1974-10-22 |
| FR2100797A1 (enrdf_load_stackoverflow) | 1972-03-24 |
| GB1338056A (en) | 1973-11-21 |
| AT309432B (de) | 1973-08-27 |
| GB1338057A (en) | 1973-11-21 |
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