IE34252B1 - Benzodiazepine derivatives - Google Patents
Benzodiazepine derivativesInfo
- Publication number
- IE34252B1 IE34252B1 IE1417/69A IE141769A IE34252B1 IE 34252 B1 IE34252 B1 IE 34252B1 IE 1417/69 A IE1417/69 A IE 1417/69A IE 141769 A IE141769 A IE 141769A IE 34252 B1 IE34252 B1 IE 34252B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- formula
- oct
- alkoxy
- halogen
- Prior art date
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title abstract 2
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rehabilitation Therapy (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Harvester Elements (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76890968A | 1968-10-18 | 1968-10-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34252L IE34252L (en) | 1970-04-18 |
| IE34252B1 true IE34252B1 (en) | 1975-03-19 |
Family
ID=25083843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1417/69A IE34252B1 (en) | 1968-10-18 | 1969-10-15 | Benzodiazepine derivatives |
Country Status (20)
| Country | Link |
|---|---|
| JP (2) | JPS4925278B1 (en, 2012) |
| AT (3) | AT302305B (en, 2012) |
| BE (1) | BE740347A (en, 2012) |
| BR (1) | BR6913309D0 (en, 2012) |
| CA (1) | CA1041498A (en, 2012) |
| CH (2) | CH554361A (en, 2012) |
| DE (1) | DE1952486A1 (en, 2012) |
| DK (1) | DK149817C (en, 2012) |
| ES (1) | ES372620A1 (en, 2012) |
| FI (1) | FI50984C (en, 2012) |
| FR (1) | FR2021010B1 (en, 2012) |
| GB (1) | GB1233489A (en, 2012) |
| HU (1) | HU166865B (en, 2012) |
| IE (1) | IE34252B1 (en, 2012) |
| IL (1) | IL33103A (en, 2012) |
| MY (1) | MY7500083A (en, 2012) |
| NL (1) | NL156141B (en, 2012) |
| NO (1) | NO127504B (en, 2012) |
| SE (3) | SE382983B (en, 2012) |
| YU (1) | YU34205B (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1812252C2 (de) * | 1968-11-26 | 1981-09-24 | Sankyo Co., Ltd., Tokyo | Benzodiazepinderivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| CH565180A5 (en, 2012) * | 1970-12-23 | 1975-08-15 | Hoffmann La Roche | |
| FR2403330A1 (fr) * | 1977-06-16 | 1979-04-13 | Fabre Sa Pierre | Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments |
| CA1166913A (en) * | 1980-06-27 | 1984-05-08 | Robert J. Thurber | Cushioned massager |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1812252C2 (de) * | 1968-11-26 | 1981-09-24 | Sankyo Co., Ltd., Tokyo | Benzodiazepinderivate, Verfahren zu ihrer Herstellung und Arzneimittel |
-
1969
- 1969-09-30 IL IL33103A patent/IL33103A/xx unknown
- 1969-09-30 CA CA063,875A patent/CA1041498A/en not_active Expired
- 1969-10-07 CH CH1502469A patent/CH554361A/xx not_active IP Right Cessation
- 1969-10-07 CH CH559472A patent/CH562247A5/xx not_active IP Right Cessation
- 1969-10-10 DK DK542069A patent/DK149817C/da not_active IP Right Cessation
- 1969-10-10 GB GB1233489D patent/GB1233489A/en not_active Expired
- 1969-10-13 NO NO04080/69A patent/NO127504B/no unknown
- 1969-10-15 BR BR213309/69A patent/BR6913309D0/pt unknown
- 1969-10-15 FI FI692974A patent/FI50984C/fi active
- 1969-10-15 IE IE1417/69A patent/IE34252B1/xx unknown
- 1969-10-16 BE BE740347D patent/BE740347A/xx not_active IP Right Cessation
- 1969-10-16 YU YU2604/69A patent/YU34205B/xx unknown
- 1969-10-17 ES ES372620A patent/ES372620A1/es not_active Expired
- 1969-10-17 AT AT981069A patent/AT302305B/de not_active IP Right Cessation
- 1969-10-17 AT AT00925/72A patent/AT303747B/de not_active IP Right Cessation
- 1969-10-17 SE SE6914318A patent/SE382983B/xx unknown
- 1969-10-17 NL NL6915750.A patent/NL156141B/xx not_active IP Right Cessation
- 1969-10-17 HU HUHO1226A patent/HU166865B/hu unknown
- 1969-10-17 AT ATA924/72A patent/AT306037B/de not_active IP Right Cessation
- 1969-10-17 FR FR696935610A patent/FR2021010B1/fr not_active Expired
- 1969-10-17 DE DE19691952486 patent/DE1952486A1/de active Granted
- 1969-10-18 JP JP44082993A patent/JPS4925278B1/ja active Pending
-
1972
- 1972-11-29 SE SE7215570A patent/SE398232B/xx unknown
-
1973
- 1973-01-12 JP JP48006492A patent/JPS4927199B1/ja active Pending
-
1975
- 1975-07-17 SE SE7508208A patent/SE420409B/xx not_active IP Right Cessation
- 1975-12-30 MY MY83/75A patent/MY7500083A/xx unknown
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