IE32928B1 - Aminoalkylbicyclocarboxylic acids - Google Patents
Aminoalkylbicyclocarboxylic acidsInfo
- Publication number
- IE32928B1 IE32928B1 IE1465/68A IE146568A IE32928B1 IE 32928 B1 IE32928 B1 IE 32928B1 IE 1465/68 A IE1465/68 A IE 1465/68A IE 146568 A IE146568 A IE 146568A IE 32928 B1 IE32928 B1 IE 32928B1
- Authority
- IE
- Ireland
- Prior art keywords
- reaction
- steps
- followed
- acid
- base
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 abstract 1
- LBLYYCQCTBFVLH-UHFFFAOYSA-N 2-Methylbenzenesulfonic acid Chemical compound CC1=CC=CC=C1S(O)(=O)=O LBLYYCQCTBFVLH-UHFFFAOYSA-N 0.000 abstract 1
- 238000003512 Claisen condensation reaction Methods 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000001567 anti-fibrinolytic effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 238000010531 catalytic reduction reaction Methods 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000002615 fibrolytic effect Effects 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical compound ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000006722 reduction reaction Methods 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69040467A | 1967-12-14 | 1967-12-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32928L IE32928L (en) | 1969-06-14 |
| IE32928B1 true IE32928B1 (en) | 1974-01-23 |
Family
ID=24772307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1465/68A IE32928B1 (en) | 1967-12-14 | 1968-12-02 | Aminoalkylbicyclocarboxylic acids |
Country Status (16)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641128A (en) * | 1969-06-17 | 1972-02-08 | Merck & Co Inc | Antifibrinolytic compounds |
| JPS4910951B1 (enrdf_load_stackoverflow) * | 1970-03-25 | 1974-03-13 | ||
| IE47589B1 (en) * | 1978-01-20 | 1984-05-02 | Daiichi Seiyaku Co | Process for producing 4-amino-methylbicyclo (2,2,2)octane-1-carboxylic acid and intermediate compound therefor |
| DE3336678A1 (de) * | 1983-10-08 | 1985-04-25 | Rudolf Wanzl Kg, 8874 Leipheim | Stapelbarer einkaufswagen mit bremsvorrichtung |
| DE19917999B4 (de) * | 1999-04-21 | 2007-01-11 | Brand Gülletechnik GmbH | Selbsttätig lösende Bremsvorrichtung für ein fahrbares Transportgerät |
-
1968
- 1968-12-01 IL IL31192A patent/IL31192A/en unknown
- 1968-12-02 IE IE1465/68A patent/IE32928B1/xx unknown
- 1968-12-02 YU YU2827/68A patent/YU33008B/xx unknown
- 1968-12-04 SE SE16572/68A patent/SE357196B/xx unknown
- 1968-12-05 ES ES361113A patent/ES361113A1/es not_active Expired
- 1968-12-05 DE DE19681812979 patent/DE1812979A1/de not_active Withdrawn
- 1968-12-09 GB GB58306/68A patent/GB1209799A/en not_active Expired
- 1968-12-09 FI FI683518A patent/FI50970C/fi active
- 1968-12-13 FR FR178116A patent/FR1605239A/fr not_active Expired
- 1968-12-13 CH CH1867168A patent/CH518262A/de not_active IP Right Cessation
- 1968-12-13 NL NL6817950A patent/NL6817950A/xx unknown
- 1968-12-13 BR BR204856/68A patent/BR6804856D0/pt unknown
- 1968-12-13 BE BE725459D patent/BE725459A/xx unknown
- 1968-12-13 DK DK611768AA patent/DK122809B/da not_active IP Right Cessation
- 1968-12-13 AT AT1216768A patent/AT289752B/de not_active IP Right Cessation
- 1968-12-13 NO NO4991/68A patent/NO125182B/no unknown
- 1968-12-13 FR FR178115A patent/FR8218M/fr not_active Expired
-
1973
- 1973-08-23 YU YU2271/73A patent/YU34393B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU33008B (en) | 1976-03-31 |
| SE357196B (enrdf_load_stackoverflow) | 1973-06-18 |
| FI50970C (fi) | 1976-09-10 |
| BR6804856D0 (pt) | 1973-03-20 |
| FI50970B (enrdf_load_stackoverflow) | 1976-05-31 |
| NL6817950A (enrdf_load_stackoverflow) | 1969-06-17 |
| NO125182B (enrdf_load_stackoverflow) | 1972-07-31 |
| BE725459A (enrdf_load_stackoverflow) | 1969-06-13 |
| GB1209799A (en) | 1970-10-21 |
| CH518262A (de) | 1972-01-31 |
| YU34393B (en) | 1979-07-10 |
| YU227173A (en) | 1978-12-31 |
| YU282768A (en) | 1975-08-31 |
| FR1605239A (enrdf_load_stackoverflow) | 1973-08-31 |
| DK122809B (da) | 1972-04-17 |
| IE32928L (en) | 1969-06-14 |
| IL31192A (en) | 1972-03-28 |
| IL31192A0 (en) | 1969-02-27 |
| FR8218M (enrdf_load_stackoverflow) | 1970-09-21 |
| DE1812979A1 (de) | 1969-07-24 |
| AT289752B (de) | 1971-05-10 |
| ES361113A1 (es) | 1970-08-01 |
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