IE32504B1 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
IE32504B1
IE32504B1 IE1425/68A IE142568A IE32504B1 IE 32504 B1 IE32504 B1 IE 32504B1 IE 1425/68 A IE1425/68 A IE 1425/68A IE 142568 A IE142568 A IE 142568A IE 32504 B1 IE32504 B1 IE 32504B1
Authority
IE
Ireland
Prior art keywords
alkyl
hal
benzodiazepine derivatives
phch2
subst
Prior art date
Application number
IE1425/68A
Other languages
English (en)
Other versions
IE32504L (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IE32504L publication Critical patent/IE32504L/xx
Publication of IE32504B1 publication Critical patent/IE32504B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE1425/68A 1967-11-24 1968-11-22 Benzodiazepine derivatives IE32504B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (2)

Publication Number Publication Date
IE32504L IE32504L (en) 1969-05-24
IE32504B1 true IE32504B1 (en) 1973-08-22

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1425/68A IE32504B1 (en) 1967-11-24 1968-11-22 Benzodiazepine derivatives

Country Status (13)

Country Link
AT (1) AT280290B (OSRAM)
BE (1) BE724364A (OSRAM)
BR (1) BR6804236D0 (OSRAM)
CH (1) CH523265A (OSRAM)
DE (1) DE1810423B2 (OSRAM)
DK (1) DK124950B (OSRAM)
ES (2) ES360410A1 (OSRAM)
FR (2) FR1593335A (OSRAM)
GB (1) GB1173540A (OSRAM)
IE (1) IE32504B1 (OSRAM)
IL (1) IL31146A (OSRAM)
NL (1) NL6815755A (OSRAM)
SE (1) SE356979B (OSRAM)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
CA2372150C (en) * 1999-04-30 2011-08-30 The Regents Of The University Of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7144880B2 (en) 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
AU2006203946B2 (en) 2005-01-03 2009-07-23 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
JP2008545757A (ja) 2005-06-01 2008-12-18 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 溶媒和されていないベンゾジアゼピン組成物および方法
EP1948191B1 (en) 2005-11-01 2013-01-16 The Regents of the University of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2418206A3 (en) 2006-06-09 2012-06-27 The Regents of the University of Michigan Benzodiazepine derivatives useful in the treatment of autoimmune disorders
JP5383513B2 (ja) 2007-03-09 2014-01-08 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 化合物およびその標的に関連する組成物ならびに方法
US9096546B2 (en) 2007-05-10 2015-08-04 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
WO2009036175A2 (en) 2007-09-14 2009-03-19 The Regents Of The University Of Michigan F1f0-atpase inhibitors and related methods
AU2008323945B2 (en) 2007-11-06 2013-11-28 The Regents Of The University Of Michigan Benzodiazepinone compounds useful in the treatment of skin conditions
US8497307B2 (en) 2008-09-11 2013-07-30 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
US8604023B2 (en) 2009-04-17 2013-12-10 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
JP2013505258A (ja) 2009-09-18 2013-02-14 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ベンゾジアゼピノン化合物およびそれを使用する治療方法
CN102753544A (zh) 2009-11-17 2012-10-24 密执安大学评议会 具有治疗性能的1，4-苯并二氮杂*-2，5-二酮和相关化合物
JP5856063B2 (ja) 2009-11-17 2016-02-09 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物
EP3043790B1 (en) * 2013-09-11 2021-05-26 The Administrators of the Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
IE32504L (en) 1969-05-24
FR8310M (OSRAM) 1970-11-23
DE1810423B2 (de) 1973-03-22
GB1173540A (en) 1969-12-10
ES378977A1 (es) 1973-01-16
NL6815755A (OSRAM) 1969-05-28
SE356979B (OSRAM) 1973-06-12
IL31146A (en) 1972-04-27
CH523265A (de) 1972-05-31
AT280290B (de) 1970-04-10
BE724364A (OSRAM) 1969-05-22
DE1810423A1 (de) 1969-10-09
FR1593335A (OSRAM) 1970-05-25
IL31146A0 (en) 1969-01-29
DE1810423C3 (OSRAM) 1973-10-11
BR6804236D0 (pt) 1973-02-08
ES360410A1 (es) 1970-11-01
DK124950B (da) 1972-12-11

Similar Documents

Publication Publication Date Title
IE32504B1 (en) Benzodiazepine derivatives
NO307053B1 (no) 0-alkylerte rapamycinderivater samt farmasøytiske preparater inneholdende derivatene
IE39078L (en) Substituted 1,3,5 - triazines.
IE36725L (en) Tetrazole derivatives.
JO1704B1 (en) New potent compounds
IE35209L (en) 3, 4-dihydroisoquinoline derivatives.
ES8106310A1 (es) Un procedimiento para la preparacion de un compuesto de ce- falosporina
ES8602649A1 (es) Procedimiento para preparar 4-hidroximetil-pirrolidinonas substituidas en posicion 1
GR3036157T3 (en) 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation.
IE40217L (en) Preparation of chlorinated phenyl-hydroxylamines.
IE37080B1 (en) New antibacterial compositions
MY104109A (en) Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza-9a-homoerythromycin a derivatives.
IE780514L (en) Morphine derivatives
CS179926B2 (en) Dispensator for insecticide agents,especially against cockroaches
ES8205214A1 (es) Un procedimiento para la preparacion de un derivado de 3-o- desmetilsannamicina c o del antibiotico ax-127b-1.
ES8207507A1 (es) Un procedimiento para la preparacion de un compuesto de platino.
IE40850L (en) 7 - methoxycephalosporins
IE42285L (en) Butirosin-a derivatives
AU548292B2 (en) 3-3-demethyl derivatives of istamycin b series compounds
IE33218L (en) 1,5-benzodiazepines
FI841739A7 (fi) Heterosyklyylialempialkyyli-penem- yhdisteet, menetelmä niiden valmistamiseksi, näitä yhdisteitä sisältävfarmaseuttiset valmisteet ja viimemainittujen käyttö.
ES8205809A1 (es) Un procedimiento para la preparacion de derivados de metoxi-cefalosporinas
IE41466L (en) 2, 4-dioxo-1-pyrimidinylcephalosporin derivatives
GB1174626A (en) New Benzoxazine Derivatives
DE3461806D1 (en) 2-desoxyoxanosine, a process for the preparation thereof and its use as a medicament