ID22876A - Turunan quinolin-4-karboksamida sebagai penerima antagonis nk-2 dan nk-3 - Google Patents

Turunan quinolin-4-karboksamida sebagai penerima antagonis nk-2 dan nk-3

Info

Publication number
ID22876A
ID22876A IDW991432A ID991432A ID22876A ID 22876 A ID22876 A ID 22876A ID W991432 A IDW991432 A ID W991432A ID 991432 A ID991432 A ID 991432A ID 22876 A ID22876 A ID 22876A
Authority
ID
Indonesia
Prior art keywords
quinolin
carboxamide
antagonists
recipient
degree
Prior art date
Application number
IDW991432A
Other languages
English (en)
Indonesian (id)
Inventor
Giuseppe Arnaldo Mari Giardina
Mario Grugni
Devide Graziani
Luca Francesco Raveglia
Original Assignee
Smithkline Beecham Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9710750.2A external-priority patent/GB9710750D0/en
Priority claimed from IT002354 external-priority patent/IT1295358B1/it
Priority claimed from ITMI972775 external-priority patent/IT1296976B1/it
Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa
Publication of ID22876A publication Critical patent/ID22876A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW991432A 1997-05-23 1998-05-18 Turunan quinolin-4-karboksamida sebagai penerima antagonis nk-2 dan nk-3 ID22876A (id)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9710750.2A GB9710750D0 (en) 1997-05-23 1997-05-23 Novel compounds
IT002354 IT1295358B1 (it) 1997-10-17 1997-10-17 Derivati chinolinici procedimento per la loro preparazione e uso come antagonisti del recettore nk3
ITMI972775 IT1296976B1 (it) 1997-12-16 1997-12-16 Derivati chinolinici procedimento per la loro preparazione e uso come antagonisti del recettore nk3

Publications (1)

Publication Number Publication Date
ID22876A true ID22876A (id) 1999-12-16

Family

ID=27268859

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991432A ID22876A (id) 1997-05-23 1998-05-18 Turunan quinolin-4-karboksamida sebagai penerima antagonis nk-2 dan nk-3

Country Status (26)

Country Link
EP (1) EP0983262B1 (pt)
JP (1) JP2002500645A (pt)
CN (1) CN1264378A (pt)
AP (1) AP9901695A0 (pt)
AR (1) AR012732A1 (pt)
AT (1) ATE244711T1 (pt)
AU (1) AU8209898A (pt)
BG (1) BG104009A (pt)
BR (1) BR9809652A (pt)
CA (1) CA2291111A1 (pt)
CO (1) CO4950515A1 (pt)
DE (1) DE69816290T2 (pt)
DZ (1) DZ2498A1 (pt)
EA (1) EA199901062A1 (pt)
ES (1) ES2201509T3 (pt)
HU (1) HUP0002300A3 (pt)
ID (1) ID22876A (pt)
IL (1) IL133036A0 (pt)
MA (1) MA26501A1 (pt)
NO (1) NO995711L (pt)
OA (1) OA11515A (pt)
PE (1) PE75199A1 (pt)
PL (1) PL336942A1 (pt)
SK (1) SK159299A3 (pt)
TR (1) TR199902883T2 (pt)
WO (1) WO1998052942A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR021354A1 (es) * 1998-11-20 2002-07-17 Smithkline Beecham Spa Procedimiento para la preparacion de un compuesto derivado de quinolina y un procedimiento para preparar una composicion farmaceutica
US6780875B2 (en) * 1998-11-20 2004-08-24 Smithkline Beecham S.P.A. Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists
GB9825554D0 (en) * 1998-11-20 1999-01-13 Smithkline Beecham Spa Novel Compounds
US6413982B1 (en) 1999-03-29 2002-07-02 Neurogen Corporation 4-substituted quinoline derivatives
AU4802500A (en) 1999-04-26 2000-11-10 Neurogen Corporation 2-aminoquinolinecarboxamides: neurokinin receptor ligands
AU2001276556A1 (en) * 2000-08-11 2002-02-25 Smithkline Beecham P.L.C. Novel pharmaceutical use of quinnoline derivatives
EP1334089A1 (en) * 2000-11-13 2003-08-13 GlaxoSmithKline S.p.A. Quinoline derivatives as nk-3 and nk-2 antagonists
GB0028964D0 (en) * 2000-11-28 2001-01-10 Smithkline Beecham Spa Novel compounds
EP1351953A1 (en) * 2000-11-28 2003-10-15 GlaxoSmithKline S.p.A. Quinoline derivatives as nk-3 antagonists
US6540733B2 (en) 2000-12-29 2003-04-01 Corazon Technologies, Inc. Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion
GB0109122D0 (en) * 2001-04-11 2001-05-30 Smithkline Beecham Spa Novel compounds
DE60208178T2 (de) * 2001-04-11 2006-08-24 Glaxosmithkline S.P.A. Chinolin-4-carboxamidderivate als nk-3 und nk-2 rezeptor antagonisten
MY134211A (en) * 2001-05-18 2007-11-30 Smithkline Beecham Corp Novel use
GB0425077D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
GB0425075D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
GB0425076D0 (en) * 2004-11-12 2004-12-15 Smithkline Beecham Corp Novel compounds
US20080200500A1 (en) * 2005-06-03 2008-08-21 Astrazeneca Ab Quinoline Derivatives as Nk3 Antagonists
GB0515580D0 (en) 2005-07-29 2005-09-07 Merck Sharp & Dohme Therapeutic compounds
AR057130A1 (es) 2005-09-21 2007-11-14 Astrazeneca Ab Quinolinas de alquilsulfoxido y una composicion farmaceutica
DE202007017299U1 (de) * 2007-12-12 2009-04-23 Drebo Werkzeugfabrik Gmbh Bohrer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3664492B2 (ja) * 1994-05-27 2005-06-29 スミスクライン・ビーチャム・ファーマシューティチ・ソシエタ・ペル・アチオニ タチキニン ｎｋ▲下３▼ 受容体アンタゴニストとしてのキノリン誘導体
AR004735A1 (es) * 1995-11-24 1999-03-10 Smithkline Beecham Spa Quinoleina 4-amido sustituida, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso de los mismos para lapreparacion de un medicamento.

Also Published As

Publication number Publication date
BR9809652A (pt) 2001-09-11
NO995711L (no) 2000-01-19
BG104009A (en) 2000-07-31
AP9901695A0 (en) 1999-12-31
DE69816290D1 (de) 2003-08-14
CN1264378A (zh) 2000-08-23
PL336942A1 (en) 2000-07-17
WO1998052942A1 (en) 1998-11-26
SK159299A3 (en) 2000-06-12
HUP0002300A3 (en) 2002-01-28
AR012732A1 (es) 2000-11-08
JP2002500645A (ja) 2002-01-08
CA2291111A1 (en) 1998-11-26
MA26501A1 (fr) 2004-12-20
ES2201509T3 (es) 2004-03-16
EP0983262B1 (en) 2003-07-09
EP0983262A1 (en) 2000-03-08
IL133036A0 (en) 2001-03-19
EA199901062A1 (ru) 2000-08-28
DZ2498A1 (fr) 2003-01-25
OA11515A (en) 2004-02-04
DE69816290T2 (de) 2004-05-27
AU8209898A (en) 1998-12-11
HUP0002300A2 (hu) 2001-06-28
ATE244711T1 (de) 2003-07-15
CO4950515A1 (es) 2000-09-01
NO995711D0 (no) 1999-11-22
TR199902883T2 (xx) 2000-05-22
PE75199A1 (es) 1999-10-22

Similar Documents

Publication Publication Date Title
ID22876A (id) Turunan quinolin-4-karboksamida sebagai penerima antagonis nk-2 dan nk-3
ID26099A (id) Turunan amida dan antagonis nosiseptin
ID29434A (id) Kombinasi-kombinasi herbisida dan pengaman
ID27031A (id) Komposisi farmasi bersalut enterik dan metode pembuatannya
ID19253A (id) Bahan antagonis reseptor vitronektin, pembuatannya dan penggunaannya
NO995852L (no) Ny form av S-omeprazol
ID23575A (id) Pirazolopirimidina-pirazolopirimidina dan pirazolotriazina-pirazolotriazina
ID16862A (id) Komposisi-komposisi elastomer dan metoda-metoda pembuatannya
DE69712003D1 (de) Modifikation von xylanase zur Verbesserung von Thermophilicität, alkophilicität und thermostabilität
DE60132709D1 (de) Bestimmung der wirksamen zusammensetzung von kohlenwasserstoffgasen
MA26668A1 (fr) ACTIVATEURS DE hPPARy ET hPPARa
ID22956A (id) Sintesa disulfida dan polisulfida organik
PL347721A1 (en) Quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists
ID29688A (id) Lampu berbentuk lampu pijar dan metoda pembuatan lampu
ID26599A (id) Turunan triazola dan imidazola
ID24196A (id) Komposisi dan penggunaan
ID19245A (id) Antagonis reseptor vitronektin, pembuatannya dan pemakaiannya
ATE227724T1 (de) Muscarinagonisten und antagonisten
ID22916A (id) Turunan-turunan ergolin dan penggunaannya sebagai antagonis reseptor somatostatin
ID27255A (id) Lampu berbentuk lampu pijar dan metoda pembuatannya
ATE274024T1 (de) Sauerstoffabsorbierende zusammensetzung und ihre anwendungsmethode
ID28732A (id) Kombinasi dari pengental-pengental asosatif dan komposisi penyalut pelindung berair
ZA200204635B (en) Fragments and antagonists of heat shock protein 60.
ID23258A (id) Penarik pemberian-menyilang dan metodenya
ID28368A (id) Tanda-tanda mikrosatelite tumbuhan dan metode terhadap penggunaannya