ID22067A - Senyawa-senyawa yang berguna untuk inhibisi transferase protein farnesil - Google Patents
Senyawa-senyawa yang berguna untuk inhibisi transferase protein farnesilInfo
- Publication number
- ID22067A ID22067A IDW990089D ID990089D ID22067A ID 22067 A ID22067 A ID 22067A ID W990089 D IDW990089 D ID W990089D ID 990089 D ID990089 D ID 990089D ID 22067 A ID22067 A ID 22067A
- Authority
- ID
- Indonesia
- Prior art keywords
- compounds
- protein transferase
- infection
- formula
- farnesil
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 102000004357 Transferases Human genes 0.000 title abstract 2
- 108090000992 Transferases Proteins 0.000 title abstract 2
- 229950008696 farnesil Drugs 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71022596A | 1996-09-13 | 1996-09-13 | |
| US87745397A | 1997-06-17 | 1997-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID22067A true ID22067A (id) | 1999-08-26 |
Family
ID=27108399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW990089D ID22067A (id) | 1996-09-13 | 1997-09-11 | Senyawa-senyawa yang berguna untuk inhibisi transferase protein farnesil |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0942906B1 (cs) |
| JP (1) | JP2002515052A (cs) |
| KR (1) | KR20000068550A (cs) |
| CN (1) | CN1248253A (cs) |
| AT (1) | ATE281450T1 (cs) |
| AU (1) | AU7243298A (cs) |
| BR (1) | BR9712035A (cs) |
| CA (1) | CA2264511C (cs) |
| CZ (1) | CZ84299A3 (cs) |
| DE (1) | DE69731481T2 (cs) |
| ES (1) | ES2232888T3 (cs) |
| HU (1) | HUP0000240A2 (cs) |
| ID (1) | ID22067A (cs) |
| IL (1) | IL128930A0 (cs) |
| NO (1) | NO991231L (cs) |
| NZ (1) | NZ334342A (cs) |
| PL (1) | PL332279A1 (cs) |
| SK (1) | SK33299A3 (cs) |
| TR (1) | TR199901273T2 (cs) |
| WO (1) | WO1998030558A2 (cs) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| KR920014799A (ko) * | 1991-01-18 | 1992-08-25 | 나오가따 다이도 | 신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제 |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| AU698960B2 (en) * | 1993-10-15 | 1998-11-12 | Schering Corporation | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| SG48750A1 (en) * | 1993-10-15 | 1998-05-18 | Schering Corp | Tricyclic carbonate compounds useful for inhabition of g-protein function for treatment of proliferative diseases |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| HU228352B1 (en) * | 1995-12-22 | 2013-03-28 | Merck Sharp & Dohme | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1997
- 1997-09-11 EP EP97955043A patent/EP0942906B1/en not_active Expired - Lifetime
- 1997-09-11 PL PL97332279A patent/PL332279A1/xx unknown
- 1997-09-11 ID IDW990089D patent/ID22067A/id unknown
- 1997-09-11 TR TR1999/01273T patent/TR199901273T2/xx unknown
- 1997-09-11 NZ NZ334342A patent/NZ334342A/xx unknown
- 1997-09-11 AU AU72432/98A patent/AU7243298A/en not_active Abandoned
- 1997-09-11 CA CA002264511A patent/CA2264511C/en not_active Expired - Fee Related
- 1997-09-11 JP JP52496198A patent/JP2002515052A/ja not_active Ceased
- 1997-09-11 WO PCT/US1997/024295 patent/WO1998030558A2/en not_active Ceased
- 1997-09-11 IL IL12893097A patent/IL128930A0/xx unknown
- 1997-09-11 AT AT97955043T patent/ATE281450T1/de not_active IP Right Cessation
- 1997-09-11 HU HU0000240A patent/HUP0000240A2/hu unknown
- 1997-09-11 DE DE69731481T patent/DE69731481T2/de not_active Expired - Fee Related
- 1997-09-11 KR KR1019997002124A patent/KR20000068550A/ko not_active Withdrawn
- 1997-09-11 CN CN97199595A patent/CN1248253A/zh active Pending
- 1997-09-11 ES ES97955043T patent/ES2232888T3/es not_active Expired - Lifetime
- 1997-09-11 BR BR9712035A patent/BR9712035A/pt unknown
- 1997-09-11 CZ CZ99842A patent/CZ84299A3/cs unknown
- 1997-09-11 SK SK332-99A patent/SK33299A3/sk unknown
-
1999
- 1999-03-12 NO NO991231A patent/NO991231L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2232888T3 (es) | 2005-06-01 |
| CN1248253A (zh) | 2000-03-22 |
| CA2264511A1 (en) | 1998-07-16 |
| KR20000068550A (ko) | 2000-11-25 |
| EP0942906B1 (en) | 2004-11-03 |
| WO1998030558A3 (en) | 1998-10-08 |
| NO991231D0 (no) | 1999-03-12 |
| AU7243298A (en) | 1998-08-03 |
| EP0942906A2 (en) | 1999-09-22 |
| CA2264511C (en) | 2003-08-05 |
| WO1998030558A2 (en) | 1998-07-16 |
| DE69731481T2 (de) | 2005-10-27 |
| NO991231L (no) | 1999-05-14 |
| BR9712035A (pt) | 1999-08-24 |
| IL128930A0 (en) | 2000-02-17 |
| DE69731481D1 (de) | 2004-12-09 |
| JP2002515052A (ja) | 2002-05-21 |
| CZ84299A3 (cs) | 1999-09-15 |
| SK33299A3 (en) | 2000-06-12 |
| ATE281450T1 (de) | 2004-11-15 |
| NZ334342A (en) | 2000-07-28 |
| HUP0000240A2 (hu) | 2001-04-28 |
| PL332279A1 (en) | 1999-08-30 |
| TR199901273T2 (xx) | 1999-09-21 |
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