ID18983A - Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia - Google Patents

Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia

Info

Publication number
ID18983A
ID18983A IDP973793A ID973793A ID18983A ID 18983 A ID18983 A ID 18983A ID P973793 A IDP973793 A ID P973793A ID 973793 A ID973793 A ID 973793A ID 18983 A ID18983 A ID 18983A
Authority
ID
Indonesia
Prior art keywords
secression
pirazola
secretary
human
pancreas phospholipase
Prior art date
Application number
IDP973793A
Other languages
English (en)
Indonesian (id)
Inventor
Peter Jeremy Doman
Gary Alan Hite
Edward David Mihelich
Tulio Nmn Suarez
Stuart Edmund Willetts
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID18983A publication Critical patent/ID18983A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44Oxygen and nitrogen or sulfur and nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
IDP973793A 1996-12-04 1997-11-27 Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia ID18983A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3321696P 1996-12-04 1996-12-04

Publications (1)

Publication Number Publication Date
ID18983A true ID18983A (id) 1998-05-28

Family

ID=21869147

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP973793A ID18983A (id) 1996-12-04 1997-11-27 Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia

Country Status (22)

Country Link
US (1) US5972972A (es)
EP (1) EP0846687B1 (es)
JP (1) JP2002515053A (es)
KR (1) KR20000057366A (es)
AR (1) AR010743A1 (es)
AT (1) ATE203985T1 (es)
AU (1) AU5365598A (es)
BR (1) BR9713993A (es)
CA (1) CA2274048A1 (es)
CO (1) CO4910169A1 (es)
DE (1) DE69706027T2 (es)
DK (1) DK0846687T3 (es)
ES (1) ES2160897T3 (es)
HK (1) HK1011865A1 (es)
HU (1) HUP0000292A3 (es)
ID (1) ID18983A (es)
IL (1) IL130202A0 (es)
PE (1) PE20599A1 (es)
PT (1) PT846687E (es)
TW (1) TW432051B (es)
WO (1) WO1998024437A1 (es)
ZA (1) ZA9710878B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
AU7726898A (en) 1997-05-22 1998-12-11 G.D. Searle & Co. Pyrazole derivatives as p38 kinase inhibitors
US6979686B1 (en) 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
US6407104B1 (en) 1998-03-31 2002-06-18 Shionogi & Co., Ltd. Pyrrolo[1,2-a]pyrazine spla2 inhibitor
KR20010034881A (ko) 1998-05-21 2001-04-25 시오노 요시히코 sPLA2 억제 효과를 갖는 피롤로[1,2-b]피리다진 유도체
AU6004799A (en) * 1998-10-14 2000-05-01 Shionogi & Co., Ltd. Remedies or preventives for ischemic reflow failure
AU6015600A (en) 1999-07-19 2001-02-05 Shionogi & Co., Ltd. Tricyclic compounds having spla2-inhibitory activities
AU6023200A (en) 1999-08-02 2001-02-19 Shionogi & Co., Ltd. Tricyclic compounds having spla2-inhibitory activities
AU6473600A (en) 1999-08-23 2001-03-19 Shionogi & Co., Ltd. Pyrrolotriazine derivatives having spla2-inhibitory activities
ES2171116B1 (es) * 2000-04-14 2003-08-01 Esteve Quimica Sa Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol.
WO2002000256A1 (en) 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Remedies for cirrhosis
JPWO2002000621A1 (ja) 2000-06-29 2004-04-22 塩野義製薬株式会社 X型sPLA2阻害作用を有する化合物
TWI314457B (es) 2001-03-19 2009-09-11 Shionogi & Co
US7076539B2 (en) * 2001-07-30 2006-07-11 Hewlett-Packard Development Company, L.P. Network connectivity establishment at user log-in
US20040018533A1 (en) * 2002-06-04 2004-01-29 Adam Gail Isabel Reid Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
US20050014158A1 (en) * 2002-06-27 2005-01-20 Adam Gail Isabel Reid Therapeutic methods for reducing fat deposition and treating associated conditions
US20050239077A1 (en) * 2002-06-27 2005-10-27 Adam Gail I R Diagnosing predisposition to fat deposition and associated conditions
EP2500340A1 (en) * 2008-01-25 2012-09-19 Syngenta Participations AG. 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides
NZ624963A (en) 2009-04-29 2016-07-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
CN105017134A (zh) * 2015-07-26 2015-11-04 陈吉美 一种4-吡啶丙烯酸的制备方法
US11066417B2 (en) 2018-02-15 2021-07-20 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators
TW202115092A (zh) 2019-08-14 2021-04-16 美商維泰克斯製藥公司 囊腫纖維化跨膜傳導調節蛋白之調節劑
MX2022001828A (es) 2019-08-14 2022-06-08 Vertex Pharma Formas cristalinas de moduladores del regulador de conductancia transmembrana de la fibrosis quistica (cftr).
TW202120517A (zh) 2019-08-14 2021-06-01 美商維泰克斯製藥公司 製備cftr調節劑之方法
WO2022076628A1 (en) * 2020-10-07 2022-04-14 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3616681A1 (de) * 1986-05-16 1987-11-19 Bayer Ag 1-aralkylpyrazole
JPH02229169A (ja) * 1989-03-01 1990-09-11 Takeda Chem Ind Ltd ピラゾロン誘導体
JPH02229168A (ja) * 1989-03-01 1990-09-11 Takeda Chem Ind Ltd ピラゾロン誘導体
EP0465913B1 (en) * 1990-07-10 1997-09-10 Ishihara Sangyo Kaisha, Ltd. Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them
EP0539034A1 (en) * 1991-10-22 1993-04-28 Konica Corporation A novel photographic cyan coupler
US5541213A (en) * 1993-06-24 1996-07-30 Eisai Co., Ltd. Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5500439A (en) * 1993-12-09 1996-03-19 Alteon Inc. Aminopyrazoles
US5559137A (en) * 1994-05-16 1996-09-24 Smithkline Beecham Corp. Compounds
US5486534A (en) * 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation

Also Published As

Publication number Publication date
HK1011865A1 (en) 1999-07-23
PE20599A1 (es) 1999-03-05
IL130202A0 (en) 2000-06-01
HUP0000292A2 (hu) 2001-04-28
WO1998024437A1 (en) 1998-06-11
EP0846687B1 (en) 2001-08-08
CA2274048A1 (en) 1998-06-11
EP0846687A1 (en) 1998-06-10
ATE203985T1 (de) 2001-08-15
TW432051B (en) 2001-05-01
JP2002515053A (ja) 2002-05-21
ES2160897T3 (es) 2001-11-16
DE69706027T2 (de) 2002-03-14
CO4910169A1 (es) 2000-04-24
DK0846687T3 (da) 2001-10-08
KR20000057366A (ko) 2000-09-15
US5972972A (en) 1999-10-26
ZA9710878B (en) 1999-06-03
AU5365598A (en) 1998-06-29
AR010743A1 (es) 2000-07-12
PT846687E (pt) 2001-12-28
HUP0000292A3 (en) 2002-01-28
DE69706027D1 (de) 2001-09-13
BR9713993A (pt) 2000-02-08

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