ID18076A - Ligan sub-tipe reseptor dopamin spirosiklik - Google Patents
Ligan sub-tipe reseptor dopamin spirosiklikInfo
- Publication number
- ID18076A ID18076A IDP972950A ID972950A ID18076A ID 18076 A ID18076 A ID 18076A ID P972950 A IDP972950 A ID P972950A ID 972950 A ID972950 A ID 972950A ID 18076 A ID18076 A ID 18076A
- Authority
- ID
- Indonesia
- Prior art keywords
- spirosiclic
- dopamin
- ligan
- receptors
- sub
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2479796P | 1996-08-26 | 1996-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID18076A true ID18076A (id) | 1998-02-26 |
Family
ID=21822443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDP972950A ID18076A (id) | 1996-08-26 | 1997-08-25 | Ligan sub-tipe reseptor dopamin spirosiklik |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6664258B1 (id) |
| EP (1) | EP0925291B1 (id) |
| JP (1) | JP3152941B2 (id) |
| AP (1) | AP9701075A0 (id) |
| AR (1) | AR013836A1 (id) |
| AT (1) | ATE311377T1 (id) |
| AU (1) | AU3632297A (id) |
| CA (1) | CA2264549C (id) |
| CO (1) | CO4560554A1 (id) |
| DE (1) | DE69734774D1 (id) |
| GT (1) | GT199700096A (id) |
| HN (1) | HN1997000117A (id) |
| HR (1) | HRP970455A2 (id) |
| ID (1) | ID18076A (id) |
| IL (1) | IL128050A0 (id) |
| IS (1) | IS4969A (id) |
| MA (1) | MA26437A1 (id) |
| PA (1) | PA8436501A1 (id) |
| PE (1) | PE108498A1 (id) |
| TN (1) | TNSN97143A1 (id) |
| WO (1) | WO1998008835A1 (id) |
| ZA (1) | ZA977597B (id) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0953567A3 (en) | 1998-04-29 | 2003-04-02 | Pfizer Products Inc. | Bicyclic substituted piperazine-, piperidine- and tetrahydropyridine derivatives, their preparation and their use as agents with central dopaminergic (dopamine D4 receptor) activity |
| US6673799B1 (en) * | 1998-09-22 | 2004-01-06 | Yamanouchi Pharmaceutical Co. Ltd. | Cyanophenyl derivative |
| EP1177792A3 (en) * | 2000-07-27 | 2002-10-23 | Pfizer Products Inc. | Dopamine D4 Ligands for the treatment of novelty-seeking disorders |
| GB0328906D0 (en) | 2003-12-12 | 2004-01-14 | Syngenta Participations Ag | Chemical compounds |
| WO2013072705A1 (en) | 2011-11-18 | 2013-05-23 | Heptares Therapeutics Limited | Muscarinic m1 receptor agonists |
| GB201513743D0 (en) | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
| GB201617454D0 (en) * | 2016-10-14 | 2016-11-30 | Heptares Therapeutics Limited | Pharmaceutical compounds |
| GB201810239D0 (en) | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201819960D0 (en) | 2018-12-07 | 2019-01-23 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB202020191D0 (en) | 2020-12-18 | 2021-02-03 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758919A (fr) * | 1969-11-15 | 1971-05-13 | Merck Patent Gmbh | Spiro-composes |
| US4010201A (en) * | 1974-04-12 | 1977-03-01 | The Upjohn Company | Organic compounds |
| US4025558A (en) * | 1974-04-12 | 1977-05-24 | The Upjohn Company | Organic compounds |
| US3932425A (en) * | 1974-04-12 | 1976-01-13 | The Upjohn Company | Benzospiran derivatives |
| DE2818329A1 (de) * | 1978-04-26 | 1979-11-08 | Yoshitomi Pharmaceutical | Spiro eckige klammer auf cyclohexan- 1,9'-thioxanthen eckige klammer zu -verbindungen |
| CA2091204C (en) * | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
| DE69325662T2 (de) | 1992-10-23 | 2000-02-10 | Merck Sharp & Dohme Ltd., Hoddesdon | Dopamin rezeptor subtyp liganden |
| GB9317631D0 (en) | 1993-08-25 | 1993-10-13 | Bxl Plastics Ltd | Multi-layered composite |
| US5403846A (en) * | 1993-11-22 | 1995-04-04 | Merck & Co., Inc. | Spirocycles |
| CA2189634A1 (en) * | 1994-05-06 | 1995-11-16 | John J. Baldwin | Combinatorial dihydrobenzopyran library |
| GB9410031D0 (en) | 1994-05-19 | 1994-07-06 | Merck Sharp & Dohme | Therapeutic agents |
-
1997
- 1997-08-08 AT AT97932964T patent/ATE311377T1/de not_active IP Right Cessation
- 1997-08-08 CA CA002264549A patent/CA2264549C/en not_active Expired - Fee Related
- 1997-08-08 EP EP97932964A patent/EP0925291B1/en not_active Expired - Lifetime
- 1997-08-08 US US09/242,819 patent/US6664258B1/en not_active Expired - Fee Related
- 1997-08-08 IL IL12805097A patent/IL128050A0/xx unknown
- 1997-08-08 WO PCT/IB1997/000978 patent/WO1998008835A1/en active IP Right Grant
- 1997-08-08 AU AU36322/97A patent/AU3632297A/en not_active Abandoned
- 1997-08-08 JP JP51143198A patent/JP3152941B2/ja not_active Expired - Fee Related
- 1997-08-08 DE DE69734774T patent/DE69734774D1/de not_active Expired - Lifetime
- 1997-08-12 HN HN1997000117A patent/HN1997000117A/es unknown
- 1997-08-19 PE PE1997000731A patent/PE108498A1/es not_active Application Discontinuation
- 1997-08-21 AP APAP/P/1997/001075A patent/AP9701075A0/en unknown
- 1997-08-22 HR HR60/024,797A patent/HRP970455A2/hr not_active Application Discontinuation
- 1997-08-22 CO CO97048585A patent/CO4560554A1/es unknown
- 1997-08-22 AR ARP970103835A patent/AR013836A1/es unknown
- 1997-08-22 PA PA19978436501A patent/PA8436501A1/es unknown
- 1997-08-25 TN TNTNSN97143A patent/TNSN97143A1/fr unknown
- 1997-08-25 ZA ZA977597A patent/ZA977597B/xx unknown
- 1997-08-25 ID IDP972950A patent/ID18076A/id unknown
- 1997-08-25 MA MA24775A patent/MA26437A1/fr unknown
- 1997-08-25 GT GT199700096A patent/GT199700096A/es unknown
-
1999
- 1999-02-05 IS IS4969A patent/IS4969A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR013836A1 (es) | 2001-01-31 |
| TNSN97143A1 (fr) | 2005-03-15 |
| EP0925291A1 (en) | 1999-06-30 |
| HRP970455A2 (en) | 1998-08-31 |
| EP0925291B1 (en) | 2005-11-30 |
| CA2264549A1 (en) | 1998-03-05 |
| MA26437A1 (fr) | 2004-12-20 |
| ZA977597B (en) | 1999-02-25 |
| DE69734774D1 (de) | 2006-01-05 |
| GT199700096A (es) | 1999-02-16 |
| AU3632297A (en) | 1998-03-19 |
| CO4560554A1 (es) | 1998-02-10 |
| IS4969A (is) | 1999-02-05 |
| ATE311377T1 (de) | 2005-12-15 |
| HN1997000117A (es) | 1997-12-26 |
| JP3152941B2 (ja) | 2001-04-03 |
| WO1998008835A1 (en) | 1998-03-05 |
| PA8436501A1 (es) | 2000-05-24 |
| AP9701075A0 (en) | 1997-10-31 |
| JP2000502360A (ja) | 2000-02-29 |
| IL128050A0 (en) | 1999-11-30 |
| CA2264549C (en) | 2004-09-14 |
| US6664258B1 (en) | 2003-12-16 |
| PE108498A1 (es) | 1999-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO995967D0 (no) | Mykningsmiddelbehandlet, absorberende interlabial gjenstand | |
| NO970979D0 (no) | Perforeringsanordning | |
| TR199500945A1 (tr) | Sübstitüe edilmis bifeniloksazolinler. | |
| ATE203528T1 (de) | Antineurodegenerativ wirksame 10-aminoaliphatyl- dibenz- b,f oxepine | |
| ID18076A (id) | Ligan sub-tipe reseptor dopamin spirosiklik | |
| DE69702795D1 (de) | Sortierer | |
| ES1029041Y (es) | Detector menstrual. | |
| DK0874814T3 (da) | 25-hydroxy-16-en-26,27-bishomo-cholecalciferoler | |
| FI1592U1 (fi) | Spruta, foeretraedesvis injektionsspruta | |
| FI972881A (fi) | Kuidutusmenetelmä | |
| ES1032571Y (es) | Gafa, | |
| KR960012943U (ko) | 전등 점, 소등장치 | |
| FI963062A0 (fi) | Dubbelblad foer stoetblad, skopa, schaktblad | |
| FI944648A0 (fi) | Bromsmekanism foer fordon, saerskilt foer en cykel | |
| FI945785A0 (fi) | Pimpelspoe, fiskeredokap | |
| FIU940180U0 (fi) | Baotstege, kaerra, landgaong | |
| FI1507U1 (fi) | Bokstaever, tecken och siffror | |
| FI940498A0 (fi) | System foer uppsamling, haemtning och mottagning av sorterade sopor | |
| FI1391U1 (fi) | Utrymme, saosom bastu av elementkonstruktion | |
| FI962118A0 (fi) | Foerbaettrad anordning foer behandling av roekgaser, saerskilt avgaser | |
| FI964381A0 (fi) | Foerfarande foer rengoering av nedsmutsat material, saosom jordmaterial | |
| FI942133A0 (fi) | Skydd foer skyddande av varor, maenniskor och liknande | |
| FI945027A0 (fi) | Foerfarande foer faestande av en kabelraenna, faeste och kabelraenna | |
| ES1033877Y (es) | Nueva caperuza-precinto. | |
| ES1033250Y (es) | Nueva lapida. |