HUT77707A - Detergent composition comprising a dimethicone copolyol for cleaning denture - Google Patents

Description

Letergen containing dimethyl copolyol

THE PROCTER & GAMBLE COMPANY, CINCINNATI, Ohio, US Date filed December 12, 1995.

Priority: 12/12/1994 22, the number 9425931.4 of the International Application PCT / US95 / 16673 International Publication Number WO 96/19563, the invention -frárgynt Hnri-inverting ké.c; 7i h ményplr; suitable for cleaning -eisŐSOrbnmnŰf ^ í line cleaners képezjjc _r - --cnfíélyekben enhanced antiplaque activity kiyáJjá -'- 'fbgtisztító affect external appearance _z XIX ± ___ ^ 4earí in solubility properties, and impact-baktériuiaeüQnes ± kalnrd2haLúságg the FRI-associated · ^-}

Compositions of the invention include an inorganic persal bleach, a effervescent agent and the like

CH3

CH3

CH3-SiO-SiO

CH3

CH3

CH3

SiO (CH ₂ ) 3

0- (C 2 H 4 O) _x - (C 3 H 6 O) _{y X}

CH3

SiOCH3

jm

CH3

Si-CH3

CH3 contains an alkyl and alkoxy-dimethicone copolyol of formula (I) wherein X is hydrogen, (C1-C16) -alkyl, alkoxy and acyl; Y is C 8 -C 22 alkyl and alkoxy; n = 0-200; m = 1-40; q = 1 to 100; the molecular weight of the group - (C ₂ H ₄ O-) _x (C ₃ H ₆ O-) _y X is between 1 and 2 g 50-2000; and the values of x and y are such that the weight ratio of the oxyethylene / oxypropylene groups is tertiary | (100: 0) - (0: 100).

Ρ9800684

DISCLOSURE

PÉLSÁNY

SBG- & ^κ · office

64 046 / BE

THE PROCTER & GAMBLE COMPANY, CINCINNATI, Ohio, US

inventors

HUGHES Iain Allan, WEYBRIDGE, SURREY, GB RYAN Elizabeth Mary, ISLEWORTH, MIDDLESEX, GB WHITE Christopher David, RICHMOND, SURREY, GB

Date of filing: 13.12.1995

Priority: 9425931.4, 22.12.1994, GB

International Application Number: PCT / US95 / 16673

International Publication Number WO 96/19563

FIELD OF THE INVENTION The present invention relates to cleaning compositions, in particular to cleaning agents for denture cleaning. In particular, the present invention relates to denture cleaners in which enhanced anti-plaque activity is associated with excellent dental cleaning, appearance, physical and solubility properties, antibacterial activity and applicability.

Effervescent tablets and powders for cleaning dentures are well known preparations. The purpose of using denture cleaners is to clean the denture as thoroughly and quickly as possible, primarily to remove plaque, mucus and bacterial deposits that build up on the denture during use. Not only is dental plaque completely free of plaque and bacterial deposits, it is not only hygienic, but in a short time leads to damage to the mucous membrane. In addition, bacterial deposition can lead to so-called bacterial corrosion of the plastic, which causes discoloration of the denture and the formation of a bad odor.

Dental care compositions are known to be associated with silicones that are said to coat the tooth and prevent puncture and staining. GB-A-689 679, for example, discloses an organopolysiloxane-containing mouthwash for preventing or removing adherence to tar, dirt, tartar and food particles.

US-A-2 806 814 discloses dentifrice compositions having a longer chain aliphatic derived from an aminocarboxylic acid

They contain the active ingredient acylamide and a silicone compound. The silicone compound is used to prevent or facilitate removal of tars, stains, tartar and similar impurities on the tooth. It is claimed that the silicone compound synergistically enhances the antimicrobial and antacid activity of the active ingredient. Particularly preferred are dimethylpolysiloxane compounds.

U.S. Pat. No. 3,624,120 discloses cyclic siloxane polymer quaternary ammonium salts useful as cationic surfactants, bactericides and anticancer agents.

However, dentures are generally made from plastics, such as an acrylic acid derivative, and plaque build-up and removal of plaque from a denture are fundamentally different from preventing and removing plaque build-up on a tooth enamel.

BACKGROUND OF THE INVENTION The present invention relates to a denture cleanser which, in addition to effective removal of plaque, mucus and bacterial deposits, provides excellent denture cleansing, appearance, physical properties, solubility and applicability.

The present invention relates to a denture cleanser comprising an inorganic persal bleach, an effervescent agent and a dimethicone copolyol, which may be an alkyl and alkoxymethoxymetonic copolyol of formula (I):

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CH3

CH3 S1OCH3

CH3

SiOCH3

• CH 3 SiO (CH ₂₎ 3

O- (C 2 H 4 O) x - (C 3 H 6 O) _r X

CH3

SiOCH3 ch ₃

Ski-CH3

CH3 (I)

In the formula:

X is hydrogen, C 1 -C 16 alkyl, alkoxy and acyl;

Y is alkyl and alkoxy of about 8 to 22 carbon atoms;

n is from about 0 to about 200;

m is from about 1 to about 40;

q is from about 1 to about 100;

the - (C2H4O-) _x (C ₃ H ₆ O-) _y X is a molecular weight of about 50 to 2000, preferably about 250 to 1,000; and x and y are such that the weight ratio of the oxyethylene / oxypropylene groups is about (100: 0) to (0: 100), preferably about (100: 0)

- (20:80).

The present invention also relates to the use of the above dimethicone copolyol as dental plaque cleansing compositions.

The percentages and ratios described herein refer to the total weight of the composition.

The denture cleansing agents of the present invention are as described above

Accordingly, it contains three essential components, a bleaching agent, a dimethicone copolyol, and a effervescent composition.

The bleaching agent is an inorganic persal and may be any well-known bleaching agent for use in denture cleansers, such as alkali metal and ammonium persulfate, perborate, percarbonate and perphosphate, and alkali metal and alkaline earth metal peroxide. Representative examples of these are potassium, ammonium, sodium and lithium persulfates and perborate mono- and tetrahydrates, sodium pyrophosphate, peroxyhydrate and magnesium, calcium, storncium and zinc peroxides. Of these, alkali metal persulfates, perborates and mixtures thereof are preferred, and alkali metal perborates are very preferred. The tablet compositions according to the invention are characterized by excellent antimicrobial activity even in the absence of alkali metal persulfates.

The amount of bleach is generally from about 5% to about 70%, preferably from about 10% to about 50%, by weight of the total composition. In compositions containing an alkali metal persulfate / perborate mixture, the weight ratio of the persulfate to perborate is suitably from about (5: 1) to (1: 5) and more preferably from about (2: 1) to (1: 2).

The compositions of the invention also contain a dimethicone copolyol anti-plaque agent. Dimethicone copolyol is generally an alkyl or alkoxydimethicone copolyol of formula (I) below

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CH ₃

CH3 SÍOCH3

CH3

SiOCH3

CH3

SiO (CH ₂ ) 3

0- (C2H4O) x (C3H6O) yX

CH3

SiOCH3

CH3 - Si-CH3 q CH3 (I) wherein:

X is hydrogen, C 1 -C 16 alkyl, alkoxy and acyl;

Y is alkyl and alkoxy of about 8 to 22 carbon atoms;

n is from about 0 to about 200;

m is from about 1 to about 40;

q is from about 1 to about 100;

the molecular weight of the group - (C ₂ H ₄ O-) _x (C ₃ H ₆ O-) _y X is from about 50 to about 2000, preferably from about 250 to about 1000; and x and y are such that the weight ratio of the oxyethylene / oxypropylene groups is about (100: 0) to (0: 100), preferably about (100: 0)

- (20:80).

In a preferred embodiment of the invention, the dimethicone copolyol may be a C12-20 alkyldimethicone copolyol and mixtures thereof. Very preferred is cetyl dimethicone copolyol under the trade name Name Abil EM90. The amount of dimethicone copolyol is generally from about 0.01% to about 25% by weight, preferably from about 0.1% to about 5% by weight, and more preferably from about 0.5% to about 1.5% by weight.

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The denture cleanser also contains, in a preferred embodiment of the invention, a solid effervescent agent that generates carbon dioxide or oxygen in the presence of water while effervescing. Suitable effervescent agents for use in the compositions of the present invention may be active in acidic, neutral or alkaline pH media, but preferred are effervescent agents which contain a combination effective or most effective in an acidic or neutral medium and an alkaline medium.

At least one alkali metal carbonate or bicarbonate, such as sodium bicarbonate, sodium carbonate, sodium sesquicarbonate, potassium bicarbonate, or at least one thereof, and mixtures thereof, containing at least one alkali metal carbonate or bicarbonate, are present in acidic or neutral media. toxic, physiologically acceptable organic acids such as tartaric acid, fumaric acid, citric acid, malic acid, maleic acid, gluconic acid, succinic acid, salicylic acid, adipic acid or sulfamic acid, sodium fumarate, acidic sodium or potassium phosphates, betaine hydrates. Of these, malic acid is preferred.

Alkaline effervescent effervescent agents contain peracids, such as alkali metal and alkaline earth metal peroxoborates, perborates, persulfates, percarbonates, perphosphates and mixtures thereof, as described above. An example of such a material is a mixture of an alkali metal perborate (anhydrous, mono- or tetrahydrate) and monopersulphate, such as Caroat commercially available from Dupont deNemours Co.

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product. This material contains a 2: 1: 1 by weight mixture of monopersulphate: potassium sulphate: potassium hydrogen sulphate and has an active oxygen content of about 4.5% by weight.

In highly preferred compositions, the solid base material comprises a (hydrogen) carbonate / acid effervescent agent and optionally combined with a perborate / persulfate oxygen effervescent agent. By combining the developers, the optimum solubility and pH conditions required for optimal cleaning and antimicrobial activity are achieved. The amount of (hydrogen) carbonate components is from about 5% to about 65% by weight, preferably from about 25% to about 55%, by weight of the total composition; and the amount of the acid component is about 5 to about 50% by weight, preferably about 10 to about 30% by weight, based on the total weight of the composition.

The compositions of the present invention may also be supplemented with other known components for the preparation of denture cleansers. An especially preferred such component is, more broadly, an organic peroxyacid precursor having a titre of at least 1.5 mL of 0.1 N sodium thiosulfate in the peracid formation assay.

The test solution is prepared by dissolving the following in 1000 ml of water:

Sodium pyrophosphate (Na ₄ P ₂ O _7. 10H ₂ O) 2.5 g of sodium perborate (NaBO _2. H ₂ O _2. 3 H ₂ O) with a release oxygen content of 10.4% by weight, 0.615 g of sodium dodecyl benzenesulfonate 0.5 g.

This solution contains so many activators at 60 ° C

64.046 / BE ····

adding that each oxygen atom present is equivalent to one molecule of introduced activator.

After the addition of the activator, the resulting mixture was stirred vigorously and kept at 60 ° C. After 5 minutes, add 100 ml of the solution and pipette immediately into a mixture of 250 g of crushed ice and 15 ml of glacial acetic acid. Then 0.4 g of potassium iodide was added and immediately titrated with 0.1 N sodium thiosulphate in the presence of a starch indicator until the first blue color disappeared. Sodium thiosulphate consumption [ml] is the titre of the bleach activator.

Organic peracid precursors are typically compounds containing one or two acyl groups prone to hydrolysis. Preferred activators are N-acyl or O-acyl compounds containing an R-CO acyl group in which R is a hydrocarbon or substituted hydrocarbon group preferably having from about 1 to about 20 carbon atoms. Suitable peracid precursors include the following:

1) Acyl organoamides of the general formula RCONRiR ₂ wherein RCO is an acyl group of a carboxylic acid, R 1 is an acyl group and R ₂ is an organic group as described in US-A-3 117 148. Representative examples of such compounds are the following:

a) N, N-diacetylaniline and N-acetylphthalimide;

b) N-acylhydantoin, such as N, N'-diacetyl-5,5-dimethylhydantoin;

(c) Polyacylated alkylene diamines such as N, N, N ', N'-tetraacetyl ethylenediamine (TAED) and the corresponding hexamethylene 64.046 / BE ···· ····· · ··

-diamine (TAHD) derivatives as disclosed in GB-A-907 356, GB-A-907 357 and GB-A-907 358;

d) Acylated glycouryl derivatives such as tetraacetyl glycouryl as disclosed in GB-A-1 246 338, GB-A-1 246 339 and GB-A-1 247 429;

2) Acylated sulfonamides, such as N-methyl-N-benzoylmethanesulfonamide and N-phenyl-N-acetylmethanesulfonamide as disclosed in GB-A-3 183 266;

3) Carboxylic acid esters as disclosed in GB-A-836 988, GB-A-963 135 and GB-A-1 147 871. Representative examples thereof are phenylacetate, sodium acetoxybenzosulfonate, trichloroethyl acetate, sorbitol hexaacetate, fructose pentaacetate, p-nitrobenzaldehyde diacetate, isopropenyl acetate, acetylacetahydroxamic acid and acetyl. salicylic acid. Other examples are phenol esters and alpha-chlorinated lower aliphatic carboxylic acid substituted phenolic compounds such as chloroacetylphenol and chloroacetylsalicylic acid as disclosed in US-A-3 130 165.

4) Carboxylic acid esters of the formula AcL wherein Ac is an acyl group derived from an organic carboxylic acid containing an optionally substituted linear or branched C 6-20 alkyl or alkenyl group or a C 6-20 alkyl substituted aryl group; and L is a leaving group; the conjugated acid has a pKa of 4 to 13, such as oxybenzenesulfonate or oxybenzoate. The following are preferred compounds of this type

64.046 / BE materials in which:

a) Ac is R ₃ -CO and R ₃ is a linear or branched alkyl group containing 6 to 20 carbon atoms, preferably 6 to 12 carbon atoms and more preferably 7 to 9 carbon atoms, and the longest alkyl chain attached to the carbonyl group being together with the carbon atom of the carbonyl group, having from 5 to 18 carbon atoms, preferably from 5 to 10 carbon atoms, R _{3 being} optionally substituted (preferably in the alpha position with respect to the carbonyl group) by chlorine or bromine or OCH ₃ or OC ₂ H ₅ . Examples of this group include: sodium 3,5,5-trimethylhexanoyloxybenzenesulfonate, sodium 3,5,5-trimethylhexanoyloxybenzoate, sodium 2-ethylhexanoyloxybenzenesulfonate , sodium nonanoyloxybenzenesulfonate and sodium octanoyloxybenzenesulfonate; the acyloxy group is preferably in the p position in each compound.

b) Ac is _R3 (AO) _to a group of formula X, and R ₃ represents a linear or branched alkyl or alkylaryl group containing from 6 to 20 carbon atoms, preferably 6-15 carbon atoms in the alkyl group; R _{3 is} optionally substituted with chloro or bromo or OCH ₃ or OC ₂ H ₅ ; AO is oxyethylene or oxypropylene; m is from 0 to 100; X is O or NR ₄ or CO-NR ₄ ; and A is CO, CO-CO, R-CO-, CO-R-CO- or _{CO-NR4 -R6} -CO, R ₄ is C 1-4 alkyl; and Rg is alkylene, alkenylene, arylene or alkarylene in the alkylene or alkenylene group containing from 1 to 8 carbon atoms. Bleach activator compounds of this type include carboxylic acid derivatives of formula R ₃ (AO) _m OCOL, succinic derivatives of formula R ₃ OCO (CH ₂ ) ₂ COL, glycollic acid derivatives of R ₃ OCH ₂ COL, hydroxypropionic acid of formula R ₃ OCH ₂ CH ₂ COL derivatives, oxalic acid derivatives of the formula R ₃ OCOCOL, maleic acid and fumaric acid derivatives of the formula R ₃ OCOCH = CHCOL, R ₃ COO NR! _{(CH2) 6} COL, acyl aminocaproic acid derivatives of the formula R3CONR3CH2COL acyl glycine derivatives, and R ₃ N (R _x) CO _(CH2) 4COL amino-6-oxo-caproic acid derivative, of formula wherein m is preferably 0 to 10; and R ₃ is when m is 0, C 6 -C 12 alkyl, and when m is not

C 0-9 alkyl. The meaning of the L fissionable group is as defined above.

5) Acyl cyanurates, such as triacetyl or tribenzoyl cyanurates, as disclosed in U.S. Patent 3,332,882.

6) Optionally substituted benzoic or phthalic anhydrides such as benzoic anhydride, m-chlorobenzoic anhydride and phthalic anhydride.

Of the above, organic peracid precursors of types le) and 4a) are preferred.

Preferably, the amount of peroxyacid bleach precursor, if present, is from about 0.1% to about 10%, more preferably from about 0.5% to about 5%, by weight of the total composition, and the composition is generally bleached.

64.046 / BE ···· ···························································································· (· (added) in the form of precursor agglomerate.

Preferably, the bleach precursor useful in the composition of the present invention comprises a binder or an agglomerating agent in an amount of from about 5 to about 40% by weight, more preferably from about 10 to about 30% by weight. Suitable agglomerating agents include polyvinylpyrrolidone, polyoxyethylene having a molecular weight of 20,000 to 500,000, and polyethylene glycol having a molecular weight of about 1,000 to 50,000. ), Carbowax of molecular weight 4,000 to 20,000, nonionic surfactants, sodium carboxymethylcellulose, gelatin, fatty alcohols, phosphates and polyphosphates, clays, aluminum silicates and polymeric polycarboxylates. Of the above, polyethylene glycols are very preferred, especially those having a molecular weight of about

1000 to 30,000, preferably 2000 to about 10,000.

Preferred bleach precursors for optimum solubility and pH characteristics are from about 10 to about 75%, preferably from about 20 to about 60% by weight of the peroxyacid bleaching precursor, from about 5 to about 60%, preferably from about 5 to about 50%, and more preferably from about 10% to about 40% by weight of a (hydrogen) carbonate / acid effervescent couple, from about 0% to about 20% by weight of peroxyborate and from about 5% to about 40% by weight, preferably from about 10% to about 30% by weight of agglomerating agent.

The final bleach precursor preferably has an average particle size of about 500-1500 µιη, preferably about 500-1000 µm, for optimum dissolution and aesthetic properties. In addition, the amount of bleach precursor per weight of the composition

64.046 / BE ·· «·« · »fc * ·» · β

From about 1 to about 20% by weight, preferably from about 5 to about 15% by weight.

The formulations of the present invention may be in the form of a paste, liquid, tablet, granulate or powder, however, tablet formulations are highly preferred. Tablet formulations may be in the form of monolayer or multilayer tablets.

The compositions of the present invention may also contain other ingredients commonly used in denture cleansers, such as, for example, surfactants, chelating agents, enzymes, flavoring agents, physiological coolants, antimicrobial compounds, colorants, sweeteners, tablet binders, and foaming agents. agents such as dimethyl polysiloxanes, foam stabilizers such as fatty acid sugar esters, preservatives, lubricants such as talc, magnesium stearate and fine amorphous pyrogenic silicates. The final composition preferably has a free moisture content of less than about 1% by weight, in particular less than about 0.5% by weight.

Suitable binders and fillers for use in the compositions of the present invention include: poly (vinylpyrrolidone), polyoxyethylene having a molecular weight of 20,000 to 500,000, polyethylene glycols having a molecular weight of about 1,000 to 50,000, 000 Carbowax Molecular Weight, Nonionic Surfactants, Fatty Acids, Sodium Carboxymethyl Cellulose, Gelatin, Fatty Alcohols, Clays, Polymeric Polycarboxylates, Sodium Carbonate, Calcium Carbonate, Calcium Hydroxide, Magnesium Sulfate, Magnesium , proteins, cellu64.046 / BE ·· «· Λ. · Υ- * · * «9

9 · «· 9 9 · ·· ·» · _Λ - 9 9 9 999 9 9 ·· ...... '''cellulose ethers, cellulose esters, poly (vinyl alcohol), alginic acid esters and pseudocolloidal vegetable fats. Of the above, polyethylene glycols are very preferred, especially those having a molecular weight of about 1000 to 30,000, preferably about 12,000 to 30,000.

The surfactants used in the compositions of the present invention may be selected from a variety of commercially available materials which are compatible with the other ingredients of the denture cleanser both dry and in solution. Such materials are believed to enhance the effect of the other ingredients of the formulation by facilitating their penetration into the interdermal surface and also by assisting in the removal of food residue adhering to the tooth. The dry powder or granular anionic surfactant associated with the composition may be, for example, sodium lauryl sulfate, sodium N-lauroyl sarcosinate, sodium lauryl sulfoacetate or dioctyl sodium sulfosuccinate or ricinoleyl sodium sulfosuccinate, 0.1 to 5% by weight, preferably 0.5 to 4% by weight.

Suitable cationic, nonionic and ampholytic surfactants include, for example, quaternary ammonium compounds such as cetyltrimethylammonium bromide, alkylene oxide condensation products such as ethylene or propylene oxide with fatty alcohols, phenols, fatty amines or alkanol fatty acids. , fatty acid alkanolamines per se, esters of C 8 -C 22 long chain fatty acids with polyalcohols or sugars, such as glycerol monostearate

Or sucrose monolaurate or sorbitol polyoxyethylene mono or distearate, betaines, sulfobetaines or long chain alkylaminocarboxylic acids.

Preferably, the chelating agents promote the cleaning and bleaching effect by keeping metal ions such as calcium, magnesium and heavy metal ions in solution. Suitable chelating agents include sodium tripolyphosphate, sodium acid pyrophosphate, tetrasodium pyrophosphate, amino polycarboxylate such as nitrilotriacetic acid and ethylenediaminetetraacetic acid and their salts, and polyphosphonates and amino polyphosphates, e.g. diphosphonic acid and ethylenediaminetetramethylene phosphonic acid, diethylenetriamine pentamethylene phosphonic acid and their salts. The chelating agent used is not critical, but must be compatible with the other denture cleanser components, both in the dry state and in aqueous solution. The chelating agent is preferably present in an amount of 0.1 to 60% by weight and preferably 0.5 to 30% by weight. However, the phosphonic acid chelating agent is preferably used in an amount of from about 0.1% to about 1% by weight of the composition, and more preferably from about 0.1% to about 0.5% by weight.

Suitable enzymes for use in the compositions of the present invention include proteases, alkalases, amylases, lipases, dextranases, mutanases and glucanases.

Suitable flavoring agents for use in the compositions of the present invention include, for example, gaulteria oil, oreganol oil, bay leaf oil, peppermint oil, marjoram oil, clove oil, cod oil, safflower oil, lemon oil, orange oil, anise oil, benzaldehyde oil, camphor, cedarwood oil, marjoram oil, citronella oil, lavender oil, mustard oil, fir oil, pine needle oil, rosemary 64.046 / BE • · · · oil, thyme oil, cinnamon leaf oil and mixtures thereof.

Suitable antimicrobial compounds include thymol, menthol, triclosan, 4-hexyl-resorcinol, phenol, eucalyptol, benzoic acid, benzoyl peroxide, butyl paraben, methyl paraben, propyl paraben, salicyl amides and mixtures thereof.

The following examples illustrate the invention in more detail.

- Examples 5:

The following examples illustrate representative denture cleansing tablets of the present invention. The percentages refer to the total weight of the tablet. Tablets were prepared by the following granular components compressing pressure of about 10 ⁵ kPa in a molding device.

Examples

Ingredients 1 2 [Tomei < 3 ?%] 4 5 Malic acid 12 10 15 - 14 Citric acid - 10 - 15 - Sodium carbonate 10 8 10 6 10 sulphamic 5 - - 3 3 PEG 20,000 - 3 7 8 5 PVP 40,000 6 3 - - - Sodium bicarbonate 22 19 24.5 13 23 Sodium perborate monohydrate 15 12 16 30 15 Potassium monopersulfate 15 18 13 - 14 Pyrogenic silica - 3 1 1 - talc 2 - - - - EDTA - - 1 - 3 EDTMP ¹ 1 - - 1 - Flavoring ⁵ 2 1 2 1 2 Abil EM90 ⁴ 1 5 0.5 10 1 Bleaching precursor agglomerate 9 8 10 12 10

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Bleaching precursor agglomerate: 1 2 3 4 5 TAED ² 2 - 4 5 2.5 TMHOS ³ 2 3 - - - sulphamic 2 2 2 2 3.5 Sodium bicarbonate 0.5 0.2 0.2 0.5 2 PEG 6000 2.5 2 2.4 2.5 1.5 coloring - 0.8 1.42 0.5

¹ Ethylene diamine tetramethylene phosphonic acid ² Tetraacetyl ethylene diamine ³ Sodium 3,5,5-trimethylhexanoyloxybenzenesulfonate ⁴ Cetyldimethicone copolyol ⁵ Peppermint based flavoring

1-5 above. Each of the tablets described in Examples 1 to 4 has a total weight of 3 g and a diameter of 25 mm.

1-5 above. The dentifrice cleaners of Examples 1 to 4 show an improved anti-plaque, excellent cleaning and anti-bacterial, adhesion and other beneficial physical and utility effects.

64.046 / BE • ·

Claims (8)

Patent Claims A denture cleanser comprising: an inorganic persal bleach, a sparkling agent, and CH3 -S-CH3 CH3 CH3 SiOCH3 CH3 • SiO CH3 SiO (CH ₂ ) 3 O- (C 2 H 4 O) _x - (C 3 H 6 O) _r X CH3 CH3 Ski-CH3 CH3 contains an alkyl and alkoxydimethicone copolyol of the formula (I): X is hydrogen, C 1 -C 16 alkyl, alkoxy and acyl; Y is alkyl and alkoxy of about 8 to 22 carbon atoms; n is from about 0 to about 200; m is from about 1 to about 40; q is from about 1 to about 100; the molecular weight of the group - (C ₂ H ₄ O-) _x (C ₃ H ₆ O-) _y X is from about 50 to about 2000; and x and y are such that the weight ratio of the oxyethylene / oxypropylene groups is about (100: 0) to (0: 100). Composition according to claim 1, characterized in that the dimethicone copolyol is a C12-20 alkyldimethicone copolyol and a mixture thereof. 3. The composition of claim 1 or 2 wherein the dimethicone copolyol is cetyldimethicone copolyol. Composition according to any one of claims 1 to 3, characterized in that it contains from about 0.01% to about 25% by weight, preferably from about 0.1% to about 5% by weight of dimethicone copolyol. Composition according to any one of claims 1 to 4, characterized in that the inorganic persal bleaching agent comprises one or more bleaching agents which may be an alkali metal persulfate, an alkali metal perborate and mixtures thereof. Composition according to any one of claims 1 to 5, characterized in that the effervescent agent consists of a (hydrogen) carbonate / acid pair. 7. A composition according to any one of claims 1 to 6, further comprising an organic peroxyacid bleach precursor. 8. The composition of claim 7, wherein the organic peroxyacid bleach precursor is selected from the group consisting of acylated poly (alkyldiamine), in particular tetraacetyl ethylenediamine, and a carboxylic acid ester of the formula Ac is an acyl group derived from an organic carboxylic acid containing an optionally substituted linear or branched C 6-20 alkyl or alkenyl group or a C 6-20 alkyl substituted aryl group; and L is a leaving group; the conjugated acid has a pKa of 4-13.