HUT77521A - Oligonukleotid-dendrimer konjugátumok és ezeket tartalmazó gyógyszerkészítmények - Google Patents
Oligonukleotid-dendrimer konjugátumok és ezeket tartalmazó gyógyszerkészítmények Download PDFInfo
- Publication number
- HUT77521A HUT77521A HU9702164A HU9702164A HUT77521A HU T77521 A HUT77521 A HU T77521A HU 9702164 A HU9702164 A HU 9702164A HU 9702164 A HU9702164 A HU 9702164A HU T77521 A HUT77521 A HU T77521A
- Authority
- HU
- Hungary
- Prior art keywords
- oligonucleotide
- dendrimer
- group
- conjugate
- alkylene
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH385494 | 1994-12-21 | ||
| CH4795 | 1995-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUT77521A true HUT77521A (hu) | 1998-05-28 |
Family
ID=25683356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9702164A HUT77521A (hu) | 1994-12-21 | 1995-12-13 | Oligonukleotid-dendrimer konjugátumok és ezeket tartalmazó gyógyszerkészítmények |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0790837A1 (ja) |
| JP (1) | JPH10510822A (ja) |
| AU (1) | AU4344696A (ja) |
| CA (1) | CA2206915A1 (ja) |
| FI (1) | FI972548A (ja) |
| HU (1) | HUT77521A (ja) |
| IL (1) | IL116456A0 (ja) |
| NO (1) | NO972868L (ja) |
| WO (1) | WO1996019240A1 (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5563255A (en) * | 1994-05-31 | 1996-10-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of raf gene expression |
| US5744460A (en) * | 1996-03-07 | 1998-04-28 | Novartis Corporation | Combination for treatment of proliferative diseases |
| CA2291839A1 (en) * | 1997-05-28 | 1998-12-03 | Peter E. Nielsen | Conjugated peptide nucleic acids having enhanced cellular uptake |
| GB9718129D0 (en) | 1997-08-27 | 1997-10-29 | Isis Innovation | Branched structures |
| US6287765B1 (en) * | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
| FR2906532B1 (fr) | 2006-09-28 | 2008-12-12 | Biomerieux Sa | Nouvel oligonucleotide marque |
| FR2933410B1 (fr) | 2008-07-04 | 2010-08-20 | Biomerieux Sa | Nouvelle sonde de detection |
| CN113573729A (zh) | 2019-01-10 | 2021-10-29 | 詹森生物科技公司 | 前列腺新抗原及其用途 |
| IL293051A (en) | 2019-11-18 | 2022-07-01 | Janssen Biotech Inc | calr and jak2 mutant-based vaccines and their uses |
| CN112898580B (zh) * | 2019-12-03 | 2022-11-08 | 安序源生物科技(深圳)有限公司 | 测序试剂 |
| CN112898575B (zh) * | 2019-12-03 | 2022-10-21 | 深圳清华大学研究院 | 树杈状大分子修饰的核苷酸的制备方法 |
| US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
| EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| WO2022009051A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | A method for determining responsiveness to prostate cancer treatment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2054678T5 (es) * | 1986-08-18 | 1997-09-16 | Dow Chemical Co | Conjugados estrella. |
| IL107715A0 (en) * | 1992-11-25 | 1994-02-27 | Baxter Int | Water soluble non-immunogenic polyamide cross-linking agents |
| CA2163364C (en) * | 1993-07-14 | 2009-10-27 | Francis C. Szoka, Jr. | Self-assembling polynucleotide delivery system comprising dendrimer polycations |
| IL128775A (en) * | 1994-03-07 | 2001-05-20 | Dow Chemical Co | A preparation containing a dendritic polymer in a complex with at least one unit of biological reaction sub |
| IT1270994B (it) * | 1994-03-18 | 1997-05-26 | Bracco Spa | Macromolecole ramificate a struttura poliossialchilica e loro usi |
-
1995
- 1995-12-13 WO PCT/EP1995/004933 patent/WO1996019240A1/en not_active Application Discontinuation
- 1995-12-13 EP EP95942147A patent/EP0790837A1/en not_active Withdrawn
- 1995-12-13 AU AU43446/96A patent/AU4344696A/en not_active Abandoned
- 1995-12-13 HU HU9702164A patent/HUT77521A/hu unknown
- 1995-12-13 JP JP8519486A patent/JPH10510822A/ja active Pending
- 1995-12-13 CA CA002206915A patent/CA2206915A1/en not_active Abandoned
- 1995-12-19 IL IL11645695A patent/IL116456A0/xx unknown
-
1997
- 1997-06-16 FI FI972548A patent/FI972548A/fi not_active Application Discontinuation
- 1997-06-20 NO NO972868A patent/NO972868L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI972548A0 (fi) | 1997-06-16 |
| CA2206915A1 (en) | 1996-06-27 |
| NO972868D0 (no) | 1997-06-20 |
| AU4344696A (en) | 1996-07-10 |
| JPH10510822A (ja) | 1998-10-20 |
| FI972548A (fi) | 1997-06-23 |
| IL116456A0 (en) | 1996-03-31 |
| WO1996019240A1 (en) | 1996-06-27 |
| NO972868L (no) | 1997-08-19 |
| EP0790837A1 (en) | 1997-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFD9 | Temporary protection cancelled due to non-payment of fee |