HUT68721A - Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them - Google Patents

Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them

Info

Publication number
HUT68721A
HUT68721A HU9301866A HU186693A HUT68721A HU T68721 A HUT68721 A HU T68721A HU 9301866 A HU9301866 A HU 9301866A HU 186693 A HU186693 A HU 186693A HU T68721 A HUT68721 A HU T68721A
Authority
HU
Hungary
Prior art keywords
pharmaceutical composition
composition containing
benzizoxazole
benzofuran
derivatives
Prior art date
Application number
HU9301866A
Other languages
English (en)
Other versions
HU9301866D0 (en
Inventor
Hisao Yamaguchi
Tatsuki Shiota
Takumi Takeyasu
Tsutomu Mochizuki
Kenichiro Kataoka
Hirofumi Tanabe
Mikio Ota
Masatoshi Kano
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of HU9301866D0 publication Critical patent/HU9301866D0/hu
Publication of HUT68721A publication Critical patent/HUT68721A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
HU9301866A 1990-12-28 1991-12-27 Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them HUT68721A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP41544390 1990-12-28
JP2914391 1991-01-31

Publications (2)

Publication Number Publication Date
HU9301866D0 HU9301866D0 (en) 1993-12-28
HUT68721A true HUT68721A (en) 1995-07-28

Family

ID=26367294

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9301866A HUT68721A (en) 1990-12-28 1991-12-27 Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them

Country Status (11)

Country Link
US (1) US5496853A (hu)
EP (1) EP0632031B1 (hu)
JP (1) JP3095413B2 (hu)
KR (1) KR930703281A (hu)
AT (1) ATE192446T1 (hu)
AU (1) AU652981B2 (hu)
CA (1) CA2098912A1 (hu)
DE (1) DE69132167T2 (hu)
ES (1) ES2145743T3 (hu)
HU (1) HUT68721A (hu)
WO (1) WO1992012144A1 (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0632031B1 (en) * 1990-12-28 2000-05-03 Teijin Limited Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same
US5451596A (en) * 1992-12-29 1995-09-19 Rhone Poulenc Rorer Pharmaceuticals Inc. Cycloalkyl amine bis-aryl squalene synthase inhibitors
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US6372770B1 (en) 1994-10-12 2002-04-16 Euro-Celtique, S.A. Benzoxazoles
US5665737B1 (en) * 1994-10-12 1999-02-16 Euro Celtique Sa Substituted benzoxazoles
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
ATE247655T1 (de) 1994-12-13 2003-09-15 Euro Celtique Sa Dreifachsubstituierte thioxanthine
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
CA2190708A1 (en) * 1995-12-08 1997-06-09 Johannes Aebi Aminoalkyl substituted benzo-heterocyclic compounds
US5684041A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
KR100215541B1 (ko) * 1996-04-19 1999-08-16 박원훈 벤족사졸계 비선형 광학 유도체 및 이들로부터 얻어진고분자
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
CN1297550C (zh) * 1998-12-04 2007-01-31 武田药品工业株式会社 苯并呋喃衍生物及其制备和用途
NZ544298A (en) * 2003-06-26 2009-04-30 Takeda Pharmaceutical Cannabinoid receptor modulators including benzofuran derivatives
TWI652014B (zh) 2013-09-13 2019-03-01 美商艾佛艾姆希公司 雜環取代之雙環唑殺蟲劑
CN107873027A (zh) * 2014-11-06 2018-04-03 巴斯夫欧洲公司 用于防治无脊椎动物害虫的3‑吡啶基杂双环化合物
KR101667878B1 (ko) * 2015-04-14 2016-10-19 문종섭 골유착 인공치의 안정도 측정장치 및 그 방법

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634462A (en) * 1968-06-26 1972-01-11 Fmc Corp 2 3-dihydro-2 2-dimethyl-7-aceto acetamidobenzofuran
JPS6031208B2 (ja) * 1974-07-10 1985-07-20 帝人株式会社 ポリアミド溶液
US4296240A (en) * 1980-04-24 1981-10-20 Sandoz, Inc. Silacycloalkane amides
US4297349A (en) * 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
DE3008812A1 (de) * 1980-03-07 1981-09-24 Hoechst Ag, 6000 Frankfurt Mischungen von optischen aufhellern
MA19290A1 (fr) * 1980-05-22 1982-04-01 Ciba Geigy Ag Derives du benzole,leur preparaton et leur utilisations therapeutiques .
US4649149A (en) * 1980-05-22 1987-03-10 Ciba-Geigy Corporation Process for the manufacture of novel benzazole derivatives, pharmaceutical preparations containing these derivatives, and their use
JPS60215680A (ja) * 1984-04-10 1985-10-29 Mitsubishi Chem Ind Ltd Ｎ−２，３−ジヒドロベンゾフラニルベンズアミド誘導体およびこれを有効成分とする農園芸用殺菌剤
CA1261835A (en) * 1984-08-20 1989-09-26 Masaaki Toda (fused) benz(thio)amides
GB2169283A (en) * 1985-01-02 1986-07-09 Sumitomo Chemical Co Fungicidal aniline derivatives
JPS61233742A (ja) * 1985-04-09 1986-10-18 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料
JPH075532B2 (ja) * 1985-06-04 1995-01-25 住友化学工業株式会社 ベンズアニリド誘導体およびそれを有効成分とする殺菌剤
US5002691A (en) * 1986-11-06 1991-03-26 The Clorox Company Oxidant detergent containing stable bleach activator granules
JPH0193569A (ja) * 1987-07-02 1989-04-12 Warner Lambert Co アシル‐ＣｏＡ：コレステロールアシルトランスフエラーゼのＮ‐〔（２，６‐ジ置換）フエニル〕尿素およびカルバメート阻害剤
US4847257A (en) * 1987-08-20 1989-07-11 Merck & Co., Inc. 5-Amino or substituted amino 1,2,3,-triazoles useful as antiproliferative agents
DE3740985A1 (de) * 1987-12-03 1989-06-15 Boehringer Mannheim Gmbh Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation
DE3809868A1 (de) * 1988-03-24 1989-10-05 Boehringer Mannheim Gmbh Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US5246927A (en) * 1988-08-17 1993-09-21 Ciba-Geigy Corporation Benzazole derivatives, processes for their preparation containing such compounds and the use thereof
TW199152B (hu) * 1990-11-01 1993-02-01 Takeda Pharm Industry Co Ltd
US5214206A (en) * 1990-11-07 1993-05-25 Warner-Lambert Company Aminosulfonyl urea acat inhibitors
EP0632031B1 (en) * 1990-12-28 2000-05-03 Teijin Limited Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
JP3095413B2 (ja) 2000-10-03
DE69132167D1 (de) 2000-06-08
WO1992012144A1 (fr) 1992-07-23
DE69132167T2 (de) 2000-12-14
US5496853A (en) 1996-03-05
AU9110591A (en) 1992-08-17
HU9301866D0 (en) 1993-12-28
ES2145743T3 (es) 2000-07-16
EP0632031A4 (hu) 1995-02-08
KR930703281A (ko) 1993-11-29
EP0632031B1 (en) 2000-05-03
ATE192446T1 (de) 2000-05-15
EP0632031A1 (en) 1995-01-04
AU652981B2 (en) 1994-09-15
CA2098912A1 (en) 1992-06-29

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal