HUT64327A - Process for production azolic compounds and pharmaceutical preparations containing these compounds - Google Patents

Process for production azolic compounds and pharmaceutical preparations containing these compounds

Info

Publication number
HUT64327A
HUT64327A HU9301226A HU9301226A HUT64327A HU T64327 A HUT64327 A HU T64327A HU 9301226 A HU9301226 A HU 9301226A HU 9301226 A HU9301226 A HU 9301226A HU T64327 A HUT64327 A HU T64327A
Authority
HU
Hungary
Prior art keywords
compounds
group
production
azolic
pharmaceutical preparations
Prior art date
Application number
HU9301226A
Other languages
English (en)
Other versions
HU9301226D0 (en
Inventor
Katsumi Itoh
Kenji Okonogi
Norikazu Tamura
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HU9301226D0 publication Critical patent/HU9301226D0/hu
Publication of HUT64327A publication Critical patent/HUT64327A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Coloring (AREA)
  • Polymerization Catalysts (AREA)
  • Lubricants (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HU9301226A 1992-04-28 1993-04-28 Process for production azolic compounds and pharmaceutical preparations containing these compounds HUT64327A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11040092 1992-04-28
JP2262393 1993-02-10

Publications (2)

Publication Number Publication Date
HU9301226D0 HU9301226D0 (en) 1993-07-28
HUT64327A true HUT64327A (en) 1993-12-28

Family

ID=26359882

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9301226A HUT64327A (en) 1992-04-28 1993-04-28 Process for production azolic compounds and pharmaceutical preparations containing these compounds
HU95P/P00243P HU211474A9 (en) 1992-04-28 1995-06-16 Azole compounds, their production and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00243P HU211474A9 (en) 1992-04-28 1995-06-16 Azole compounds, their production and use

Country Status (18)

Country Link
US (2) US5371101A (hu)
EP (1) EP0567982B1 (hu)
JP (1) JP2818097B2 (hu)
KR (1) KR100257619B1 (hu)
CN (1) CN1040433C (hu)
AT (1) ATE167857T1 (hu)
AU (1) AU655544B2 (hu)
CA (1) CA2094962A1 (hu)
DE (1) DE69319380T2 (hu)
DK (1) DK0567982T3 (hu)
ES (1) ES2118160T3 (hu)
FI (1) FI931901A (hu)
HU (2) HUT64327A (hu)
NO (1) NO303284B1 (hu)
NZ (1) NZ247488A (hu)
PH (1) PH31082A (hu)
SG (1) SG48939A1 (hu)
TW (1) TW218017B (hu)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212458B (en) * 1993-09-23 1996-06-28 Richter Gedeon Vegyeszet New silyloxypropane derivatives substituted with triazole or imidazole pharmaceutical compositions containing them and process for producing them
TW297813B (hu) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
CA2134417A1 (en) * 1993-12-22 1995-06-23 Katsumi Itoh Optically active azole derivatives, their production and use
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
HUT74735A (en) * 1994-02-25 1997-02-28 Takeda Chemical Industries Ltd Injectable emulsion composition containing antifungal triazole derivatives and process for producing it
CA2150533A1 (en) * 1994-05-31 1995-12-01 Katsumi Itoh Production of optically active triazole compounds and their intermediates
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
US5639754A (en) * 1994-07-12 1997-06-17 Janssen Pharmaceutica N.V. Urea and thiourea derivatives of azolones
TW318841B (hu) * 1995-02-17 1997-11-01 Takeda Pharm Industry Co Ltd
AU4675596A (en) * 1995-02-17 1996-09-04 Takeda Chemical Industries Ltd. Azole compounds, their production and use
US5700825A (en) * 1995-03-31 1997-12-23 Florida State University Radiosensitizing diamines and their pharmaceutical preparations
US6060604A (en) * 1995-03-31 2000-05-09 Florida State University Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups
DE19520597A1 (de) * 1995-06-06 1996-12-12 Bayer Ag Mercapto-bis-triazole
WO1997005131A1 (en) * 1995-08-02 1997-02-13 J. Uriach & Cia. S.A. New carboxamides with antifungal activity
ES2120885B1 (es) * 1996-03-15 1999-06-16 Uriach & Cia Sa J Nuevas tienopirimidonas con actividad antifungica.
ES2107376B1 (es) * 1995-08-02 1998-07-01 Uriach & Cia Sa J Nuevos derivados de pirimidona con actividad antifungica.
DE69611512T2 (de) * 1995-08-02 2001-05-31 J. Uriach & Cia. S.A., Barcelona Pyrimidonderivate mit antifungaler wirkung
GB9602080D0 (en) * 1996-02-02 1996-04-03 Pfizer Ltd Pharmaceutical compounds
US6001835A (en) * 1996-04-03 1999-12-14 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
CA2250353A1 (en) * 1996-04-03 1997-10-09 Christopher J. Dinsmore Inhibitors of farnesyl-protein transferase
AU6119798A (en) * 1997-03-05 1998-09-22 Takeda Chemical Industries Ltd. Crystalline form of a bis 1,2,4-triazole compound
RU2189982C2 (ru) * 1997-03-31 2002-09-27 Такеда Кемикал Индастриз, Лтд. Азольные соединения, способ их получения, противогрибковая фармацевтическая композиция и способ лечения грибковой инфекции
EP0884311A3 (en) * 1997-06-06 1999-01-27 Takeda Chemical Industries, Ltd. Triazole Derivatives and their production
US6133485A (en) * 1998-04-15 2000-10-17 Synphar Laboratories, Inc. Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols
AU5760999A (en) * 1998-09-29 2000-04-17 Takeda Chemical Industries Ltd. Antimycotic drug composition
ES2159488B1 (es) * 2000-03-07 2002-04-16 Uriach & Cia Sa J Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica.
CA2402345A1 (en) * 2000-03-07 2001-09-13 Sudershan K. Arora Azole compounds as therapeutic agents for fungal infections
IN191188B (hu) 2000-03-07 2003-10-04 Ranbaxy Lab Ltd
EP1347758A1 (en) * 2000-12-26 2003-10-01 Ranbaxy Laboratories, Ltd. Azole compounds as anti-fungals agents
ATE309226T1 (de) * 2001-03-23 2005-11-15 Richter Gedeon Vegyeszet Verfahren zur herstellung von fluconazole und kristallmodifikationen davon
IN191819B (hu) * 2001-07-19 2004-01-03 Ranbaxy Lab Ltd
IN192526B (hu) * 2001-09-25 2004-04-24 Ranbaxy Lab
US7028055B2 (en) * 2002-03-22 2006-04-11 Sun Microsystems, Inc. Method and apparatus for improving transaction specification by marking application states
EA200401336A1 (ru) * 2002-04-12 2006-02-24 Ранбакси Лабораторис Лимитед Производные 2,2,4-тризамещенного тетрагидрофурана в качестве противогрибковых средств
WO2003105841A1 (ja) * 2002-06-18 2003-12-24 ポーラ化成工業株式会社 抗真菌医薬組成物
AU2002328176A1 (en) * 2002-08-26 2004-03-11 Ranbaxy Laboratories Limited Azole derivatives as antifungal agents
KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
EP1817295B1 (en) * 2004-11-18 2012-11-07 Synta Pharmaceuticals Corp. Triazole compounds that modulate hsp90 activity
CN1304376C (zh) * 2005-03-04 2007-03-14 清华大学 一种卤化烷基咪唑型离子液体的制备方法
CA2618377A1 (en) * 2005-08-12 2007-02-22 Synta Pharmaceuticals Corp. Pyrazole compounds that modulate hsp90 activity
AU2006338265B2 (en) * 2005-08-18 2011-04-14 Synta Pharmaceuticals Corp. Triazole compounds that modulate HSP90 activity
RS53446B (en) 2006-05-25 2014-12-31 Synta Pharmaceuticals Corp. TRIAZOLE UNITS MODULATING HSP90 ACTIVITY
CA2653332A1 (en) * 2006-05-25 2007-12-06 Synta Pharmaceuticals Corp. Triazole compounds that modulate hsp90 activity
AU2007267847B2 (en) * 2006-05-25 2012-04-12 Synta Pharmaceuticals Corp. Triazole compounds that modulate Hsp90 activity
US20080027047A1 (en) * 2006-05-25 2008-01-31 Weiwen Ying Compounds that modulate HSP90 activity and methods for identifying same
EP2049504A4 (en) 2006-08-07 2010-09-22 Stiefel Laboratories ANTIFUNGAL CRYSTALLINE COMPOUNDS
AU2007312391B2 (en) * 2006-10-19 2012-06-21 F. Hoffmann-La Roche Ag Imidazolone and imidazolidinone derivatives as 11b-HSD1 inhibitors for diabetes
EP2560640A1 (en) 2010-04-19 2013-02-27 Synta Pharmaceuticals Corp. Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor
CN102824342B (zh) * 2011-06-17 2016-03-30 全哲山 一类用作抗癫痫药的化合物及其可药用盐
US9439899B2 (en) 2011-11-02 2016-09-13 Synta Pharmaceuticals Corp. Cancer therapy using a combination of HSP90 inhibitors with topoisomerase I inhibitors
JP2014534228A (ja) 2011-11-02 2014-12-18 シンタ ファーマシューティカルズ コーポレーション 白金含有剤とｈｓｐ９０阻害剤の組合せ療法
WO2013074594A1 (en) 2011-11-14 2013-05-23 Synta Pharmaceuticals Corp. Combination therapy of hsp90 inhibitors with braf inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8306351D0 (en) * 1983-03-08 1983-04-13 Ici Plc Azole fungicides
DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
NZ223799A (en) * 1987-03-25 1989-12-21 Janssen Pharmaceutica Nv Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
FI97382C (fi) * 1988-03-04 1996-12-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten 1,2,4-triatsolijohdannaisten valmistamiseksi
DE3837463A1 (de) * 1988-11-04 1990-05-10 Bayer Ag Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0567982A1 (en) 1993-11-03
AU655544B2 (en) 1994-12-22
FI931901A0 (fi) 1993-04-27
SG48939A1 (en) 1998-05-18
US5371101A (en) 1994-12-06
FI931901A (fi) 1993-10-29
AU3822193A (en) 1993-11-04
CN1040433C (zh) 1998-10-28
NO931533D0 (no) 1993-04-27
DE69319380D1 (de) 1998-08-06
NO931533L (no) 1993-10-29
KR940005616A (ko) 1994-03-21
JPH06293740A (ja) 1994-10-21
ATE167857T1 (de) 1998-07-15
TW218017B (hu) 1993-12-21
DK0567982T3 (da) 1999-04-12
ES2118160T3 (es) 1998-09-16
HU211474A9 (en) 1995-11-28
PH31082A (en) 1998-02-05
US5466820A (en) 1995-11-14
HU9301226D0 (en) 1993-07-28
NZ247488A (en) 1995-02-24
KR100257619B1 (en) 2000-07-01
DE69319380T2 (de) 1998-10-29
CA2094962A1 (en) 1993-10-29
EP0567982B1 (en) 1998-07-01
JP2818097B2 (ja) 1998-10-30
NO303284B1 (no) 1998-06-22
CN1079467A (zh) 1993-12-15

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal