HUT63615A - Process for producing new imidazole derivatives and pharmaceutical compositions comprising same as active ingredient - Google Patents
Process for producing new imidazole derivatives and pharmaceutical compositions comprising same as active ingredientInfo
- Publication number
- HUT63615A HUT63615A HU9300107A HU9300107A HUT63615A HU T63615 A HUT63615 A HU T63615A HU 9300107 A HU9300107 A HU 9300107A HU 9300107 A HU9300107 A HU 9300107A HU T63615 A HUT63615 A HU T63615A
- Authority
- HU
- Hungary
- Prior art keywords
- optionally substituted
- alkyl
- imidazole derivatives
- active ingredient
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/62—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with triarylmethyl radicals attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP557792 | 1992-01-16 |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9300107D0 HU9300107D0 (en) | 1993-04-28 |
HUT63615A true HUT63615A (en) | 1993-09-28 |
HU219917B HU219917B (hu) | 2001-09-28 |
Family
ID=11615084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9300107A HU219917B (hu) | 1992-01-16 | 1993-01-15 | Imidazolszármazékok és az ezeket hatóanyagként tartalmazó gyógyászati készítmények |
Country Status (16)
Country | Link |
---|---|
US (2) | US5326780A (hu) |
EP (2) | EP0700911B1 (hu) |
JP (1) | JP3464498B2 (hu) |
KR (1) | KR100259309B1 (hu) |
AT (2) | ATE200082T1 (hu) |
AU (1) | AU649906B2 (hu) |
CA (1) | CA2087112A1 (hu) |
DE (2) | DE69330072T2 (hu) |
DK (2) | DK0700911T3 (hu) |
ES (2) | ES2157291T3 (hu) |
GR (1) | GR3035646T3 (hu) |
HU (1) | HU219917B (hu) |
NZ (1) | NZ245674A (hu) |
PT (1) | PT700911E (hu) |
TW (1) | TW235963B (hu) |
ZA (1) | ZA93217B (hu) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300519A (en) * | 1988-07-06 | 1994-04-05 | The University Of Sheffield | Immunosuppressive agents |
US5514781A (en) * | 1994-04-11 | 1996-05-07 | Bayer Corporation | Use of azoles as virucidal agents in solutions of biologically active proteins |
US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
BR9509024A (pt) * | 1994-09-26 | 1997-09-30 | Shionogi & Co | Derivados de imidazol |
EP0893442B1 (en) * | 1996-03-28 | 2005-01-12 | Shionogi & Co., Ltd. | Lymph-absorbable imidazole derivatives |
EP0891339A1 (en) * | 1996-04-03 | 1999-01-20 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5891889A (en) * | 1996-04-03 | 1999-04-06 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
WO1997037657A1 (fr) * | 1996-04-04 | 1997-10-16 | Shionogi & Co., Ltd. | Composition anti-vih contenant un derive d'imidazole |
US6544193B2 (en) * | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
JP3378017B2 (ja) * | 1996-12-26 | 2003-02-17 | 塩野義製薬株式会社 | イミダゾール誘導体の製造法 |
TWI232214B (en) * | 1998-04-16 | 2005-05-11 | Shionogi & Co | Preparation of aryl sulfenyl halide |
US6184241B1 (en) | 1998-08-24 | 2001-02-06 | Kansas State University Research Foundation | Aspartic protease inhibitors |
US7060721B1 (en) | 1998-12-24 | 2006-06-13 | Fujisawa Pharmaceutical Co., Ltd. | Imidazole compounds and medicinal use thereof |
GB0028484D0 (en) * | 2000-11-22 | 2001-01-10 | Hoffmann La Roche | Imidazolone derivatives for the treatment of viral diseases |
MXPA03007546A (es) * | 2001-02-23 | 2004-10-15 | Leuven K U Res & Dev | Derivados de n-aminoimidazol inhibidores del vih. |
CN105682568B (zh) | 2013-11-04 | 2018-10-23 | 柯惠Lp公司 | 手术紧固件施加装置 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63150266A (ja) * | 1986-12-12 | 1988-06-22 | Mitsui Petrochem Ind Ltd | ベンジルイミダゾ−ル誘導体 |
US5668136A (en) * | 1990-09-25 | 1997-09-16 | Eisai Co., Ltd. | Trisubstituted benzene derivatives, composition and methods of treatment |
-
1993
- 1993-01-11 TW TW082100124A patent/TW235963B/zh active
- 1993-01-12 US US08/003,126 patent/US5326780A/en not_active Expired - Lifetime
- 1993-01-12 CA CA002087112A patent/CA2087112A1/en not_active Abandoned
- 1993-01-13 NZ NZ245674A patent/NZ245674A/en unknown
- 1993-01-13 ZA ZA93217A patent/ZA93217B/xx unknown
- 1993-01-13 JP JP00421693A patent/JP3464498B2/ja not_active Expired - Fee Related
- 1993-01-15 PT PT95203023T patent/PT700911E/pt unknown
- 1993-01-15 HU HU9300107A patent/HU219917B/hu not_active IP Right Cessation
- 1993-01-15 EP EP95203023A patent/EP0700911B1/en not_active Expired - Lifetime
- 1993-01-15 DK DK95203023T patent/DK0700911T3/da active
- 1993-01-15 AU AU31827/93A patent/AU649906B2/en not_active Ceased
- 1993-01-15 DE DE69330072T patent/DE69330072T2/de not_active Expired - Fee Related
- 1993-01-15 KR KR1019930000496A patent/KR100259309B1/ko not_active IP Right Cessation
- 1993-01-15 EP EP93300278A patent/EP0552060B1/en not_active Expired - Lifetime
- 1993-01-15 DK DK93300278T patent/DK0552060T3/da active
- 1993-01-15 DE DE69322106T patent/DE69322106T2/de not_active Expired - Fee Related
- 1993-01-15 AT AT95203023T patent/ATE200082T1/de not_active IP Right Cessation
- 1993-01-15 ES ES95203023T patent/ES2157291T3/es not_active Expired - Lifetime
- 1993-01-15 AT AT93300278T patent/ATE173470T1/de not_active IP Right Cessation
- 1993-01-15 ES ES93300278T patent/ES2125301T3/es not_active Expired - Lifetime
-
1994
- 1994-03-14 US US08/209,627 patent/US5472965A/en not_active Expired - Fee Related
-
2001
- 2001-03-29 GR GR20010400136T patent/GR3035646T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU219917B (hu) | 2001-09-28 |
DK0700911T3 (da) | 2001-05-07 |
NZ245674A (en) | 1995-06-27 |
DE69322106T2 (de) | 1999-04-29 |
CA2087112A1 (en) | 1993-07-17 |
AU649906B2 (en) | 1994-06-02 |
EP0700911A1 (en) | 1996-03-13 |
EP0552060B1 (en) | 1998-11-18 |
ES2125301T3 (es) | 1999-03-01 |
KR930016402A (ko) | 1993-08-26 |
JP3464498B2 (ja) | 2003-11-10 |
DE69330072D1 (de) | 2001-05-03 |
ES2157291T3 (es) | 2001-08-16 |
TW235963B (hu) | 1994-12-11 |
AU3182793A (en) | 1993-07-22 |
ZA93217B (en) | 1993-08-18 |
EP0552060A1 (en) | 1993-07-21 |
JPH05255270A (ja) | 1993-10-05 |
ATE200082T1 (de) | 2001-04-15 |
DK0552060T3 (da) | 1999-08-02 |
ATE173470T1 (de) | 1998-12-15 |
DE69330072T2 (de) | 2001-08-23 |
US5326780A (en) | 1994-07-05 |
EP0700911B1 (en) | 2001-03-28 |
PT700911E (pt) | 2001-07-31 |
US5472965A (en) | 1995-12-05 |
DE69322106D1 (de) | 1998-12-24 |
KR100259309B1 (ko) | 2000-08-01 |
GR3035646T3 (en) | 2001-06-29 |
HU9300107D0 (en) | 1993-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |