HUT54165A - Process for producing cefalosporin derivatives and pharmaceutical compositions comprising same - Google Patents

Process for producing cefalosporin derivatives and pharmaceutical compositions comprising same

Info

Publication number
HUT54165A
HUT54165A HU90172A HU17290A HUT54165A HU T54165 A HUT54165 A HU T54165A HU 90172 A HU90172 A HU 90172A HU 17290 A HU17290 A HU 17290A HU T54165 A HUT54165 A HU T54165A
Authority
HU
Hungary
Prior art keywords
producing
same
pharmaceutical compositions
cefalosporin
derivatives
Prior art date
Application number
HU90172A
Other languages
English (en)
Other versions
HU205936B (en
HU900172D0 (en
Inventor
Friedhelm Adam
Juergen Blumbach
Gerd Frischer
Walter Duerckheimer
Burkhard Mencke
Dieter Isert
Norbert Klesel
Gerhard Seibert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HU900172D0 publication Critical patent/HU900172D0/hu
Publication of HUT54165A publication Critical patent/HUT54165A/hu
Publication of HU205936B publication Critical patent/HU205936B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU90172A 1989-01-19 1990-01-17 Process for producing cephalosporing derivatives and pharmaceutical compositions containing them HU205936B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901405A DE3901405A1 (de) 1989-01-19 1989-01-19 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
HU900172D0 HU900172D0 (en) 1990-03-28
HUT54165A true HUT54165A (en) 1991-01-28
HU205936B HU205936B (en) 1992-07-28

Family

ID=6372346

Family Applications (1)

Application Number Title Priority Date Filing Date
HU90172A HU205936B (en) 1989-01-19 1990-01-17 Process for producing cephalosporing derivatives and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0379132A3 (hu)
JP (1) JPH02229196A (hu)
CN (1) CN1044280A (hu)
AU (1) AU4853690A (hu)
CA (1) CA2008059A1 (hu)
DD (1) DD291561A5 (hu)
DE (1) DE3901405A1 (hu)
FI (1) FI900270A0 (hu)
HU (1) HU205936B (hu)
IL (1) IL93086A0 (hu)
NO (1) NO900252L (hu)
NZ (1) NZ232135A (hu)
PH (1) PH27125A (hu)
PT (1) PT92890A (hu)
TN (1) TNSN90006A1 (hu)
ZA (1) ZA90361B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3804841A1 (de) * 1988-02-17 1989-08-31 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
DE59209994D1 (de) * 1991-09-07 2004-04-29 Aventis Pharma Gmbh Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
TW212181B (hu) * 1992-02-14 1993-09-01 Hoechst Ag
ES2117066T3 (es) * 1992-05-21 1998-08-01 Hoechst Ag Procedimiento para la disociacion de esteres profarmacos de cefalosporina para dar acido 7-amino-3-metoximetil-cef-3-em-4-carboxilico.
PA8579701A1 (es) 2002-08-23 2005-05-24 Pfizer Prod Inc Profarmaco inhibidor de beta-lactamasa
CN114478391B (zh) * 2020-10-26 2023-09-15 南京锐志生物医药有限公司 奥硝唑酯类前药、药物组合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS5896091A (ja) * 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
JPS604189A (ja) * 1983-06-20 1985-01-10 Sankyo Co Ltd β−ラクタム系化合物の製造法

Also Published As

Publication number Publication date
NO900252D0 (no) 1990-01-18
CN1044280A (zh) 1990-08-01
HU205936B (en) 1992-07-28
IL93086A0 (en) 1990-11-05
EP0379132A3 (de) 1992-01-08
HU900172D0 (en) 1990-03-28
DD291561A5 (de) 1991-07-04
NO900252L (no) 1990-07-20
JPH02229196A (ja) 1990-09-11
ZA90361B (en) 1990-10-31
EP0379132A2 (de) 1990-07-25
DE3901405A1 (de) 1990-07-26
NZ232135A (en) 1991-07-26
PH27125A (en) 1992-03-16
PT92890A (pt) 1990-07-31
CA2008059A1 (en) 1990-07-19
TNSN90006A1 (fr) 1991-03-05
FI900270A0 (fi) 1990-01-17
AU4853690A (en) 1990-07-26

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee