HUT47151A - Process for producing new hybrid plasminogen activator compounds - Google Patents

Process for producing new hybrid plasminogen activator compounds

Info

Publication number
HUT47151A
HUT47151A HU883362A HU336288A HUT47151A HU T47151 A HUT47151 A HU T47151A HU 883362 A HU883362 A HU 883362A HU 336288 A HU336288 A HU 336288A HU T47151 A HUT47151 A HU T47151A
Authority
HU
Hungary
Prior art keywords
plasminogen activator
producing new
new hybrid
activator compounds
hybrid plasminogen
Prior art date
Application number
HU883362A
Other languages
English (en)
Inventor
Michael J Browne
Jeffery Hugh Robinson
Richard A Smith
Sarkis B Kalindjian
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878715392A external-priority patent/GB8715392D0/en
Priority claimed from GB878715391A external-priority patent/GB8715391D0/en
Priority claimed from GB878719279A external-priority patent/GB8719279D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of HUT47151A publication Critical patent/HUT47151A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
HU883362A 1987-07-01 1988-06-29 Process for producing new hybrid plasminogen activator compounds HUT47151A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878715392A GB8715392D0 (en) 1987-07-01 1987-07-01 Compounds
GB878715391A GB8715391D0 (en) 1987-07-01 1987-07-01 Compounds
GB878719279A GB8719279D0 (en) 1987-08-14 1987-08-14 Compounds

Publications (1)

Publication Number Publication Date
HUT47151A true HUT47151A (en) 1989-01-30

Family

ID=27263478

Family Applications (1)

Application Number Title Priority Date Filing Date
HU883362A HUT47151A (en) 1987-07-01 1988-06-29 Process for producing new hybrid plasminogen activator compounds

Country Status (11)

Country Link
EP (1) EP0297882B1 (hu)
JP (1) JPS6480287A (hu)
AU (1) AU615919B2 (hu)
DE (1) DE3883453T2 (hu)
DK (1) DK359888A (hu)
FI (1) FI883146A (hu)
HU (1) HUT47151A (hu)
IL (1) IL86909A0 (hu)
NO (1) NO882886L (hu)
NZ (1) NZ225215A (hu)
PT (1) PT87869B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826975D0 (en) * 1988-11-18 1988-12-21 Beecham Group Plc Novel compounds
AU6470590A (en) 1989-10-23 1991-04-26 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
GB8927722D0 (en) * 1989-12-07 1990-02-07 British Bio Technology Proteins and nucleic acids
GB9011861D0 (en) * 1990-05-26 1990-07-18 Beecham Group Plc Novel compounds
GB9013345D0 (en) * 1990-06-14 1990-08-08 Beecham Group Plc Novel compounds
GB9019120D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
WO1999016889A1 (en) * 1997-10-01 1999-04-08 G.D. Searle & Co. Fusion proteins comprising an angiostatin moiety and their use in anti-tumor treatment
US6984373B2 (en) 2000-12-23 2006-01-10 Dyax Corp. Fibrin binding moieties useful as imaging agents
WO2002094954A1 (en) * 2001-05-21 2002-11-28 Nippon Paint Co., Ltd. Process for producing high-concentration colloidal metal solution

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
DE3361610D1 (en) * 1982-04-07 1986-02-06 Beecham Group Plc Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
GB8609948D0 (en) * 1986-04-23 1986-05-29 Beecham Group Plc Compounds
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
US4916071A (en) * 1985-08-14 1990-04-10 American Home Products Corporation Poly-kringle plasminogen activator
IE81073B1 (en) * 1986-03-18 2000-01-12 Genentech Inc Modified human tissue-type plasminogen activator and its preparation

Also Published As

Publication number Publication date
AU615919B2 (en) 1991-10-17
JPS6480287A (en) 1989-03-27
DK359888D0 (da) 1988-06-29
AU1853388A (en) 1989-01-19
NZ225215A (en) 1991-05-28
FI883146A0 (fi) 1988-06-30
PT87869B (pt) 1995-03-01
EP0297882B1 (en) 1993-08-25
NO882886L (no) 1989-01-02
EP0297882A3 (en) 1989-08-16
IL86909A0 (en) 1988-11-30
FI883146A (fi) 1989-01-02
DK359888A (da) 1989-01-02
DE3883453D1 (de) 1993-09-30
NO882886D0 (no) 1988-06-29
DE3883453T2 (de) 1994-03-17
PT87869A (pt) 1989-06-30
EP0297882A2 (en) 1989-01-04

Similar Documents

Publication Publication Date Title
HUT46707A (en) Process for producing new peptidase inhibitors
YU200985A (en) Process for producing acilated diketonic compounds
HUT39190A (en) Process for producing new compounds
YU10988A (en) Process for avermectine producing
HUT38339A (en) Process for producing dihydropyridine-carbonyl compounds
HU892602D0 (en) Process for producing 9-hydroxi-17-methylene-steroides as well as their usage for producing cortico-steroides
EP0288994A3 (en) Process for producing optically active compounds
HUT52487A (en) Process for producing mono-n-alkyl-polyaza-makroring compounds
HUT54409A (en) Process for producing new somatotropin-analogues
HUT53582A (en) Process for producing 1-butene
HUT47151A (en) Process for producing new hybrid plasminogen activator compounds
HU903160D0 (en) Process for producing new compounds
EP0208486A3 (en) Process for producing tissue plasminogen activator
EP0289942A3 (en) Process for producing fluorobenzaldehydes
HUT48637A (en) Process for producing sialocyl-glycerolipides
HU905944D0 (en) Process for producing new macrolidic compounds
GB8407768D0 (en) Process for producing beta-lactam compounds
HUT46009A (en) Process for producing 7-bromo-beta-carboline compounds
EP0304010A3 (en) Process for producing carbon materials
GB2209166B (en) Process for producing trialkylarsenic compound
HU906514D0 (en) Process for producing phenoxi-heterocyclic compounds
GB2161802B (en) Process for producing n-chlorosulfenyl compounds
HU905041D0 (en) Process for producing 3-fluoro-4-amino-phenol
HUT47244A (en) Process for producing azetidine derivatives
HUT48639A (en) Process for producing 4-demetoxy-antracyclin derivatives

Legal Events

Date Code Title Description
DFC9 Refusal of application