HUT43591A - Process for production of derivatives 4-/2-piramidinil/-1-piperasine heterocyclic carbonil and medical compounds containing thereof as active substance - Google Patents

Process for production of derivatives 4-/2-piramidinil/-1-piperasine heterocyclic carbonil and medical compounds containing thereof as active substance

Info

Publication number
HUT43591A
HUT43591A HU87904A HU90487A HUT43591A HU T43591 A HUT43591 A HU T43591A HU 87904 A HU87904 A HU 87904A HU 90487 A HU90487 A HU 90487A HU T43591 A HUT43591 A HU T43591A
Authority
HU
Hungary
Prior art keywords
piramidinil
piperasine
carbonil
heterocyclic
derivatives
Prior art date
Application number
HU87904A
Other languages
English (en)
Other versions
HU197567B (en
Inventor
Marcel Hibert
Maurice Gittos
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of HUT43591A publication Critical patent/HUT43591A/hu
Publication of HU197567B publication Critical patent/HU197567B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU87904A 1986-03-05 1987-03-04 Process for producing heterocyclic carbonyl derivatives of 4-(2-pyrimidinyl)-1-piperazine and pharmaceuticals comprising same as active ingredient HU197567B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83627786A 1986-03-05 1986-03-05

Publications (2)

Publication Number Publication Date
HUT43591A true HUT43591A (en) 1987-11-30
HU197567B HU197567B (en) 1989-04-28

Family

ID=25271609

Family Applications (1)

Application Number Title Priority Date Filing Date
HU87904A HU197567B (en) 1986-03-05 1987-03-04 Process for producing heterocyclic carbonyl derivatives of 4-(2-pyrimidinyl)-1-piperazine and pharmaceuticals comprising same as active ingredient

Country Status (18)

Country Link
EP (1) EP0238905B1 (hu)
JP (1) JPH0778043B2 (hu)
KR (1) KR900000413B1 (hu)
CN (1) CN1023484C (hu)
AR (2) AR242678A1 (hu)
AT (1) ATE93523T1 (hu)
AU (1) AU588671B2 (hu)
CA (1) CA1286667C (hu)
DE (1) DE3787109T2 (hu)
DK (1) DK111987A (hu)
ES (1) ES2059316T3 (hu)
FI (1) FI870925A (hu)
HU (1) HU197567B (hu)
NO (1) NO167390C (hu)
NZ (1) NZ219456A (hu)
PH (1) PH24912A (hu)
PT (1) PT84408B (hu)
ZA (1) ZA871450B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003831A1 (en) * 1987-10-26 1989-05-05 Pfizer Inc. Anti-anxiety agents
SE8803429D0 (sv) * 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
HU221315B1 (en) * 1989-04-22 2002-09-28 Wyeth John & Brother Ltd Alkyl-substituted piperazine derivatives, pharmaceutical compositions containing them, and process for producing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
DE2727469A1 (de) * 1977-06-18 1978-12-21 Hoechst Ag Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
WO1989003831A1 (en) * 1987-10-26 1989-05-05 Pfizer Inc. Anti-anxiety agents
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives

Also Published As

Publication number Publication date
ATE93523T1 (de) 1993-09-15
ZA871450B (en) 1987-08-20
EP0238905A2 (en) 1987-09-30
JPS62265285A (ja) 1987-11-18
CN1023484C (zh) 1994-01-12
NO167390B (no) 1991-07-22
PT84408A (en) 1987-04-01
HU197567B (en) 1989-04-28
NO870891L (no) 1987-09-07
ES2059316T3 (es) 1994-11-16
NO167390C (no) 1991-10-30
CN87101688A (zh) 1988-03-02
KR900000413B1 (ko) 1990-01-30
EP0238905B1 (en) 1993-08-25
DE3787109T2 (de) 1994-02-10
JPH0778043B2 (ja) 1995-08-23
CA1286667C (en) 1991-07-23
DK111987A (da) 1987-09-06
AR242790A1 (es) 1993-05-31
DK111987D0 (da) 1987-03-04
AU588671B2 (en) 1989-09-21
PT84408B (pt) 1989-10-04
FI870925A (fi) 1987-09-06
KR870008874A (ko) 1987-10-21
NZ219456A (en) 1989-08-29
DE3787109D1 (de) 1993-09-30
AR242678A1 (es) 1993-04-30
NO870891D0 (no) 1987-03-04
AU6960787A (en) 1987-09-10
FI870925A0 (fi) 1987-03-03
PH24912A (en) 1990-12-26
EP0238905A3 (en) 1989-08-09

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee