HUP9904112A2 - Eljárás amidinok előállítására - Google Patents
Eljárás amidinok előállításáraInfo
- Publication number
- HUP9904112A2 HUP9904112A2 HU9904112A HUP9904112A HUP9904112A2 HU P9904112 A2 HUP9904112 A2 HU P9904112A2 HU 9904112 A HU9904112 A HU 9904112A HU P9904112 A HUP9904112 A HU P9904112A HU P9904112 A2 HUP9904112 A2 HU P9904112A2
- Authority
- HU
- Hungary
- Prior art keywords
- pipe
- mercapto
- inorganic
- carboxylic acid
- ammonium salt
- Prior art date
Links
- 150000001409 amidines Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 150000003863 ammonium salts Chemical class 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- HDFRDWFLWVCOGP-UHFFFAOYSA-N carbonothioic O,S-acid Chemical compound OC(S)=O HDFRDWFLWVCOGP-UHFFFAOYSA-N 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- -1 carbon alkyl amine Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Engine Equipment That Uses Special Cycles (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A találmány tárgya eljárás bőnyőlűlt szűbsztitűenseket tartalmazónitrilek egyszerű átalakítására a (kőnvenciőnális amidinszintézisselnem előállítható) megfelelő R-C(NHR')=NH (I) általánős képletű -, ahőlR alifás, arőmás vagy heterőciklűsős csőpőrt, és R' hidrőgénatőm, 1-6szénatőmős alkilcsőpőrt vagy aminőcsőpőrt - amidinőkká. A találmányszerinti a megfelelő nitrilt egy HS-R'-COOH általánős képletű,merkaptő- és karbőxilcsőpőrtőkőn kívül a reakció körülményei közöttrekacióképes csőpőrtőkat nem tartalmazó merkaptő-karbőnsav és adőttesetben egy szervetlen vagy szerves ammóniűmsó jelenlétébenammóniával, egy 1-6 szénatőmős alkil-aminnal vagy hidrazinnalreagáltatják. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19635674A DE19635674A1 (de) | 1996-09-03 | 1996-09-03 | Verfahren zur Herstellung von Amidinen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9904112A2 true HUP9904112A2 (hu) | 2000-05-28 |
| HUP9904112A3 HUP9904112A3 (en) | 2001-07-30 |
Family
ID=7804470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9904112A HUP9904112A3 (en) | 1996-09-03 | 1997-08-21 | Process for preparing amidines |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6204385B1 (hu) |
| EP (1) | EP0931069B1 (hu) |
| JP (1) | JP2000517325A (hu) |
| KR (1) | KR20000068410A (hu) |
| CN (1) | CN1228769A (hu) |
| AT (1) | ATE197795T1 (hu) |
| AU (1) | AU715743B2 (hu) |
| CA (1) | CA2264723A1 (hu) |
| DE (2) | DE19635674A1 (hu) |
| DK (1) | DK0931069T3 (hu) |
| ES (1) | ES2153191T3 (hu) |
| HU (1) | HUP9904112A3 (hu) |
| IL (1) | IL128338A0 (hu) |
| NO (1) | NO310865B1 (hu) |
| PL (1) | PL331893A1 (hu) |
| TW (1) | TW438776B (hu) |
| WO (1) | WO1998009950A1 (hu) |
| ZA (1) | ZA977860B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK14232001A3 (sk) | 1999-04-09 | 2002-06-04 | Basf Aktiengesellschaft | Nízkomolekulové inhibítory komplementárnych proteáz |
| PL352834A1 (en) * | 1999-04-09 | 2003-09-08 | Abbott Gmbh & Co.Kg | Prodrugs of thrombin inhibitors |
| EP1054017B1 (de) | 1999-05-10 | 2004-10-13 | Abbott GmbH & Co. KG | Salze von Thrombininhibitoren |
| GB0503672D0 (en) * | 2005-02-23 | 2005-03-30 | Astrazeneca Ab | New process |
-
1996
- 1996-09-03 DE DE19635674A patent/DE19635674A1/de not_active Withdrawn
-
1997
- 1997-08-21 JP JP10512174A patent/JP2000517325A/ja active Pending
- 1997-08-21 HU HU9904112A patent/HUP9904112A3/hu unknown
- 1997-08-21 CN CN97197606A patent/CN1228769A/zh active Pending
- 1997-08-21 PL PL97331893A patent/PL331893A1/xx unknown
- 1997-08-21 US US09/254,003 patent/US6204385B1/en not_active Expired - Fee Related
- 1997-08-21 AT AT97918992T patent/ATE197795T1/de not_active IP Right Cessation
- 1997-08-21 ES ES97918992T patent/ES2153191T3/es not_active Expired - Lifetime
- 1997-08-21 KR KR1019997001749A patent/KR20000068410A/ko not_active Application Discontinuation
- 1997-08-21 DE DE59702695T patent/DE59702695D1/de not_active Expired - Lifetime
- 1997-08-21 DK DK97918992T patent/DK0931069T3/da active
- 1997-08-21 WO PCT/EP1997/004548 patent/WO1998009950A1/de not_active Application Discontinuation
- 1997-08-21 CA CA002264723A patent/CA2264723A1/en not_active Abandoned
- 1997-08-21 AU AU42997/97A patent/AU715743B2/en not_active Ceased
- 1997-08-21 EP EP97918992A patent/EP0931069B1/de not_active Expired - Lifetime
- 1997-08-21 IL IL12833897A patent/IL128338A0/xx unknown
- 1997-09-01 TW TW086112527A patent/TW438776B/zh not_active IP Right Cessation
- 1997-09-02 ZA ZA977860A patent/ZA977860B/xx unknown
-
1999
- 1999-03-02 NO NO19991010A patent/NO310865B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO310865B1 (no) | 2001-09-10 |
| WO1998009950A1 (de) | 1998-03-12 |
| KR20000068410A (ko) | 2000-11-25 |
| EP0931069A1 (de) | 1999-07-28 |
| DE59702695D1 (de) | 2001-01-04 |
| HUP9904112A3 (en) | 2001-07-30 |
| AU715743B2 (en) | 2000-02-10 |
| ZA977860B (en) | 1999-03-02 |
| ES2153191T3 (es) | 2001-02-16 |
| PL331893A1 (en) | 1999-08-16 |
| EP0931069B1 (de) | 2000-11-29 |
| DK0931069T3 (da) | 2001-02-19 |
| US6204385B1 (en) | 2001-03-20 |
| NO991010L (no) | 1999-03-02 |
| IL128338A0 (en) | 2000-01-31 |
| CN1228769A (zh) | 1999-09-15 |
| AU4299797A (en) | 1998-03-26 |
| ATE197795T1 (de) | 2000-12-15 |
| JP2000517325A (ja) | 2000-12-26 |
| CA2264723A1 (en) | 1998-03-12 |
| DE19635674A1 (de) | 1998-03-05 |
| TW438776B (en) | 2001-06-07 |
| NO991010D0 (no) | 1999-03-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1055302A1 (en) | Aliphatic nitrogenous five-membered ring compounds | |
| DK1692115T3 (da) | Fremgangsmåde til fremstilling af 3-phenyl(thio)uraciler og 3-phenyldithiouraciler | |
| HUP9904112A2 (hu) | Eljárás amidinok előállítására | |
| Paventi et al. | Preparation of α-aminothioamides from aldehydes | |
| TW328077B (en) | Process for the preparation of thioamide | |
| DK0536939T4 (da) | Proces til fremstilling af aminopolyoler | |
| HUP0100453A1 (hu) | Eljárás izokarbamidok előállítására | |
| ES469215A1 (es) | Procedimiento para la obtencion de antranilamidas. | |
| GB1224066A (en) | N-aryl-n'-substituted amino phthalamides and their use as herbicides | |
| GB1469226A (en) | Process for the preparation of 2-2-thienyl-ethylamine and derivatives thereof | |
| ES2069942T3 (es) | Procedimiento para la obtencion de fenilureas puras n,n'-asimetricamente substituidas. | |
| GB817745A (en) | 2-thiohydantoins | |
| DE69016672T2 (de) | 4-(hetero)arylmethyloxy-phenyl-diazolderivate, verfahren zu deren herstellung und ihre therapeutische verwendung. | |
| GB765506A (en) | Improvements in the production of compounds of the pyrimidine series | |
| SE9000420D0 (sv) | A process for the manufacture of n,n-disubstitutedmandelamindes | |
| HUP9900699A1 (hu) | Eljárás malonsav-dinitril előállítására | |
| JPS5626952A (en) | Water-soluble resin composition | |
| GB1351922A (en) | Nitrofuryl-triazolo-pyridazine derivatives | |
| HUP9701658A2 (hu) | Benzopiránszármazékok alkalmazása beültetett szervkivetés megelőzésére alkalmas gyógyszerkészítmények előállítására | |
| ES8604107A1 (es) | Procedimiento de obtencion de un derivado de bencilamina y sus sales | |
| GB1174200A (en) | Process for the preparation of Pyrazinoyl-and Pyrazinamido-Guanidines | |
| ES331455A1 (es) | Un procedimiento para la preparacion de diaminas. | |
| GB895927A (en) | Production of 1-dialkylamino-4-hydroxy-acetylenes-(2) | |
| GB1203543A (en) | CYANOALKYLAMINO-s-TRIAZINES |