HUP9901633A2 - Centkromán l-enantiomer alkalmazása gyógyszerkészítmény előállítására, amely alkalmas mellrák kezelésére vagy megelőzésére - Google Patents

Centkromán l-enantiomer alkalmazása gyógyszerkészítmény előállítására, amely alkalmas mellrák kezelésére vagy megelőzésére

Info

Publication number
HUP9901633A2
HUP9901633A2 HU9901633A HUP9901633A HUP9901633A2 HU P9901633 A2 HUP9901633 A2 HU P9901633A2 HU 9901633 A HU9901633 A HU 9901633A HU P9901633 A HUP9901633 A HU P9901633A HU P9901633 A2 HUP9901633 A2 HU P9901633A2
Authority
HU
Hungary
Prior art keywords
treatment
enantiomer
breast cancer
centchroman
prophylaxis
Prior art date
Application number
HU9901633A
Other languages
English (en)
Inventor
Omkar Prasad Asthana
Ved Prakash Kamboj
Suprabhat Ray
Michael Shalmi
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP9901633A2 publication Critical patent/HUP9901633A2/hu
Publication of HUP9901633A3 publication Critical patent/HUP9901633A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A 3,4-transz-2,2-dimetil-3-fenil-4-[4-(2-(pirrőlidin-1-l)--etőxi)-fenil]-7-metőxi-krőmán l-enantiőmerjének vagy gyógyszerészetilegelfőgadható sójának felhasználására valamely gyógyszerészetilegelfőgadható hőrdőzóanyaggal együtt, gyógyszerkészítmény előállítására,amely alkalmas mellrák kezelésében vagy megelőző kezelésben történőfelhasználásra. ŕ
HU9901633A 1996-01-11 1997-01-09 Use of the l-enantiomer of centchroman for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of breast cancer HUP9901633A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1000096P 1996-01-11 1996-01-11
DK77696 1996-07-11

Publications (2)

Publication Number Publication Date
HUP9901633A2 true HUP9901633A2 (hu) 1999-10-28
HUP9901633A3 HUP9901633A3 (en) 2000-02-28

Family

ID=26064631

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901633A HUP9901633A3 (en) 1996-01-11 1997-01-09 Use of the l-enantiomer of centchroman for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of breast cancer

Country Status (12)

Country Link
EP (1) EP0873119A1 (hu)
JP (1) JP2001500101A (hu)
KR (1) KR19990077157A (hu)
AU (1) AU1367197A (hu)
BR (1) BR9706966A (hu)
CA (1) CA2241462A1 (hu)
CZ (1) CZ217198A3 (hu)
HU (1) HUP9901633A3 (hu)
IL (1) IL124881A0 (hu)
NO (1) NO983177L (hu)
PL (1) PL328135A1 (hu)
WO (1) WO1997025034A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1028724A1 (en) * 1997-11-10 2000-08-23 Novo Nordisk A/S Transdermal delivery of 3,4-diarylchromans
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
AU2004200099B2 (en) * 1998-06-11 2006-11-02 Endorecherche, Inc. Medical Uses of A Selective Estrogen Receptor Modulator in Combination with Sex Steroid Precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
AU2011253842B2 (en) * 1998-06-11 2014-08-14 Endorecherche Inc. Medical Uses of a Selective Estrogen Receptor Modulator in Combination with Sex Steroid Precursors
CN106038572A (zh) 2004-10-20 2016-10-26 恩多研究公司 性甾体前体单独或与选择性雌激素受体调节剂联合用于预防和治疗绝经后女性的性功能障碍
US8268806B2 (en) 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
CA2702710C (en) 2007-10-16 2013-05-07 Repros Therapeutics, Inc. Trans-clomiphene for metabolic syndrome
US20100317635A1 (en) 2009-06-16 2010-12-16 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
WO2011156908A1 (en) 2010-06-16 2011-12-22 Endorecherche, Inc. Methods of treating or preventing estrogen-related diseases
ES2681023T3 (es) 2012-02-29 2018-09-11 Repros Therapeutics Inc. Terapia de combinación para tratar el déficit de andrógenos
US9744177B2 (en) 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
CN108348605B (zh) 2015-11-10 2023-06-09 帕拉卡林治疗公司 用pdgf-cc抑制剂和抗雌激素治疗er阴性乳癌

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447622A (en) * 1981-09-22 1984-05-08 Council Of Scientific And Industrial Research Rafi Marg Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof

Also Published As

Publication number Publication date
KR19990077157A (ko) 1999-10-25
NO983177L (no) 1998-07-10
AU1367197A (en) 1997-08-01
CA2241462A1 (en) 1997-07-17
BR9706966A (pt) 1999-05-04
WO1997025034A1 (en) 1997-07-17
CZ217198A3 (cs) 1998-11-11
PL328135A1 (en) 1999-01-18
JP2001500101A (ja) 2001-01-09
IL124881A0 (en) 1999-01-26
EP0873119A1 (en) 1998-10-28
HUP9901633A3 (en) 2000-02-28

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