HUP9900453A2 - RAR-gamma specifikus agonista ligandum alkalmazása apoptózis arányának növelésére - Google Patents
RAR-gamma specifikus agonista ligandum alkalmazása apoptózis arányának növeléséreInfo
- Publication number
- HUP9900453A2 HUP9900453A2 HU9900453A HUP9900453A HUP9900453A2 HU P9900453 A2 HUP9900453 A2 HU P9900453A2 HU 9900453 A HU9900453 A HU 9900453A HU P9900453 A HUP9900453 A HU P9900453A HU P9900453 A2 HUP9900453 A2 HU P9900453A2
- Authority
- HU
- Hungary
- Prior art keywords
- rar
- gamma
- apoptosis rate
- specific agonist
- agonist ligand
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
- 230000006907 apoptotic process Effects 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9512179A FR2739557B1 (fr) | 1995-10-09 | 1995-10-09 | Utilisation d'un ligand agoniste specifique rar-gamma |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9900453A2 true HUP9900453A2 (hu) | 1999-05-28 |
HUP9900453A3 HUP9900453A3 (en) | 1999-11-29 |
Family
ID=9483613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9900453A HUP9900453A3 (en) | 1995-10-09 | 1996-10-08 | Use of a gamma-rar-specific agonist ligand to increase apoptosis rate |
Country Status (16)
Country | Link |
---|---|
US (4) | US6593359B1 (hu) |
EP (1) | EP0854710A2 (hu) |
JP (1) | JP3135266B2 (hu) |
KR (1) | KR19990064139A (hu) |
CN (1) | CN1121857C (hu) |
AU (1) | AU705993B2 (hu) |
BR (1) | BR9610967A (hu) |
CA (1) | CA2231561A1 (hu) |
FR (1) | FR2739557B1 (hu) |
HU (1) | HUP9900453A3 (hu) |
NO (1) | NO981592L (hu) |
NZ (1) | NZ319646A (hu) |
PL (1) | PL185826B1 (hu) |
RU (1) | RU2188037C2 (hu) |
TR (1) | TR199800645T1 (hu) |
WO (1) | WO1997013505A2 (hu) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040266715A1 (en) * | 1999-03-31 | 2004-12-30 | Wong Liang Fong | Neurite regeneration |
US20030053991A1 (en) * | 2000-10-04 | 2003-03-20 | Kingsman Alan John | Retinoic acid receptor beta-2, its agonists, and gene theraphy vectors for the treatment of neurological disorders |
US20070213290A1 (en) * | 1996-10-17 | 2007-09-13 | Kingsman Alan J | Neurite regeneration |
GB9907461D0 (en) * | 1999-03-31 | 1999-05-26 | King S College London | Neurite regeneration |
FR2757852B1 (fr) | 1996-12-31 | 1999-02-19 | Cird Galderma | Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations |
DE69835441T2 (de) * | 1997-11-12 | 2007-08-02 | F. Hoffmann-La Roche Ag | Behandlung von t-helfer zell typ 2 vermittelten immunkrankheiten mit retinoid antagonisten |
US6083973A (en) * | 1998-03-09 | 2000-07-04 | Syntex (U.S.A.) Inc. | Methods for inhibiting mucin secretion using RAR α selective antagonists |
US6949528B1 (en) * | 1998-03-18 | 2005-09-27 | Goddard John G | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof |
JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of invasive diseases, using selected anti-PAR materials |
AU2003294757A1 (en) * | 2002-11-29 | 2004-06-23 | Axxima Pharmaceuticals Ag | Formulations useful against hepatitis c virus infections |
US20050202055A1 (en) | 2004-03-11 | 2005-09-15 | Koichi Shudo, Tokyo, Japan | Anti-wrinkle agent |
JP4921351B2 (ja) * | 2004-03-26 | 2012-04-25 | ディーエスエム アイピー アセッツ ビー.ブイ. | レチノイドと組み合せたhdacインヒビターを含む組成物 |
US7713266B2 (en) | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US7850683B2 (en) * | 2005-05-20 | 2010-12-14 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US9254162B2 (en) | 2006-12-21 | 2016-02-09 | Myoscience, Inc. | Dermal and transdermal cryogenic microprobe systems |
US8409185B2 (en) | 2007-02-16 | 2013-04-02 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
WO2009065061A1 (en) | 2007-11-14 | 2009-05-22 | Myoscience, Inc. | Pain management using cryogenic remodeling |
ES2427980T3 (es) | 2008-12-22 | 2013-11-05 | Myoscience, Inc. | Sistema crioquirúrgico integrado con refrigerante y fuente de energía eléctrica |
CN103200937B (zh) | 2010-09-01 | 2020-07-03 | 托马斯杰弗逊大学 | 用于肌肉修复和再生的组合物和方法 |
BR112013033309B1 (pt) | 2011-06-24 | 2022-07-05 | Gri Bio, Inc | Uso de tazaroteno e método in vitro para inibição de ativação de células nkt tipo i |
CA2860893A1 (en) | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
CA2861116A1 (en) | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Cryogenic probe filtration system |
EP2802279B1 (en) | 2012-01-13 | 2017-08-16 | Myoscience, Inc. | Cryogenic needle with freeze zone regulation |
US9017318B2 (en) | 2012-01-20 | 2015-04-28 | Myoscience, Inc. | Cryogenic probe system and method |
US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
US9610112B2 (en) | 2013-03-15 | 2017-04-04 | Myoscience, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
US20140350536A1 (en) | 2013-03-15 | 2014-11-27 | Myoscience, Inc. | Cryogenic Blunt Dissection Methods and Devices |
WO2014146127A1 (en) | 2013-03-15 | 2014-09-18 | Myoscience, Inc. | Methods and systems for treatment of spasticity |
WO2015069792A1 (en) | 2013-11-05 | 2015-05-14 | Myoscience, Inc. | Secure cryosurgical treatment system |
PL3380086T3 (pl) | 2015-11-25 | 2022-02-21 | Io Therapeutics, Inc. | Oporne na cyp26 agonisty selektywne względem rar-alfa w leczeniu nowotworu |
EP3454762B1 (en) | 2016-05-13 | 2024-04-03 | Pacira CryoTech, Inc. | Systems for locating and treating with cold therapy |
EP3468600A4 (en) | 2016-06-10 | 2019-11-13 | IO Therapeutics, Inc. | RETINOID COMPOUNDS AND RELECTIVE REXINOIDS OF THE RECEPTOR AND IMMUNE MODULATORS FOR IMMUNOTHERAPY OF CANCER |
KR20200029544A (ko) | 2017-07-13 | 2020-03-18 | 아이오 테라퓨틱스, 인크. | 암 면역요법을 위해 면역 조절제와 조합된 면역조절 레티노이드 및 렉시노이드 화합물 |
SG11202001479RA (en) | 2017-08-31 | 2020-03-30 | Io Therapeutics Inc | Rar selective agonists in combination with immune modulators for cancer immunotherapy |
EP3709918A4 (en) | 2017-11-15 | 2021-08-11 | Pacira CryoTech, Inc. | INTEGRATED COLD THERAPY AND ELECTRIC STIMULATION SYSTEMS FOR LOCALIZATION AND TREATMENT OF NERVE AND RELATED PROCEDURES |
US11135236B2 (en) * | 2018-04-10 | 2021-10-05 | Northwestern University | Retinoic acid receptor gamma agonists to attenuate anthracycline-induced cardiotoxicity |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5786391A (en) * | 1995-01-11 | 1998-07-28 | Cornell Research Foundation, Inc. | Regulating gene expression using retinoids with Ch2 OH or related groups at the side chain terminal position |
EP0850067A4 (en) * | 1995-07-17 | 1999-12-15 | Cird Galderma | METHOD FOR CANCER TREATMENT USING 6- (3- (1-ADAMANTYL) -4-HYDROXYPHENYL) 2 NAPHTALINE CARBONIC ACID |
-
1995
- 1995-10-09 FR FR9512179A patent/FR2739557B1/fr not_active Expired - Fee Related
-
1996
- 1996-10-08 NZ NZ319646A patent/NZ319646A/xx unknown
- 1996-10-08 RU RU98108590/14A patent/RU2188037C2/ru not_active IP Right Cessation
- 1996-10-08 TR TR1998/00645T patent/TR199800645T1/xx unknown
- 1996-10-08 PL PL96326077A patent/PL185826B1/pl not_active IP Right Cessation
- 1996-10-08 EP EP96933502A patent/EP0854710A2/fr not_active Withdrawn
- 1996-10-08 KR KR1019980702620A patent/KR19990064139A/ko not_active Application Discontinuation
- 1996-10-08 CA CA002231561A patent/CA2231561A1/fr not_active Abandoned
- 1996-10-08 BR BR9610967A patent/BR9610967A/pt not_active Application Discontinuation
- 1996-10-08 AU AU72209/96A patent/AU705993B2/en not_active Ceased
- 1996-10-08 US US09/051,407 patent/US6593359B1/en not_active Expired - Fee Related
- 1996-10-08 CN CN96198769A patent/CN1121857C/zh not_active Expired - Fee Related
- 1996-10-08 JP JP09514767A patent/JP3135266B2/ja not_active Expired - Fee Related
- 1996-10-08 WO PCT/FR1996/001568 patent/WO1997013505A2/fr not_active Application Discontinuation
- 1996-10-08 HU HU9900453A patent/HUP9900453A3/hu unknown
-
1998
- 1998-04-07 NO NO981592A patent/NO981592L/no not_active Application Discontinuation
-
1999
- 1999-11-02 US US09/431,920 patent/US6686386B1/en not_active Expired - Fee Related
-
2000
- 2000-07-25 US US09/624,771 patent/US6506796B1/en not_active Expired - Fee Related
-
2001
- 2001-03-09 US US09/801,664 patent/US20010018456A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6686386B1 (en) | 2004-02-03 |
AU7220996A (en) | 1997-04-30 |
NO981592L (no) | 1998-06-09 |
TR199800645T1 (xx) | 1998-06-22 |
US6506796B1 (en) | 2003-01-14 |
WO1997013505A3 (fr) | 1997-05-29 |
NO981592D0 (no) | 1998-04-07 |
FR2739557A1 (fr) | 1997-04-11 |
US20010018456A1 (en) | 2001-08-30 |
WO1997013505A2 (fr) | 1997-04-17 |
CN1121857C (zh) | 2003-09-24 |
CN1203528A (zh) | 1998-12-30 |
RU2188037C2 (ru) | 2002-08-27 |
JP3135266B2 (ja) | 2001-02-13 |
AU705993B2 (en) | 1999-06-03 |
PL326077A1 (en) | 1998-08-17 |
KR19990064139A (ko) | 1999-07-26 |
JPH11501661A (ja) | 1999-02-09 |
US6593359B1 (en) | 2003-07-15 |
PL185826B1 (pl) | 2003-08-29 |
HUP9900453A3 (en) | 1999-11-29 |
EP0854710A2 (fr) | 1998-07-29 |
BR9610967A (pt) | 1999-03-02 |
FR2739557B1 (fr) | 1997-11-14 |
CA2231561A1 (fr) | 1997-04-17 |
NZ319646A (en) | 2000-08-25 |
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