HUP9803035A2 - 7-Bróm- és 7,7-dibróm-cefám és -cefém-származékok - Google Patents

7-Bróm- és 7,7-dibróm-cefám és -cefém-származékok

Info

Publication number
HUP9803035A2
HUP9803035A2 HU9803035A HUP9803035A HUP9803035A2 HU P9803035 A2 HUP9803035 A2 HU P9803035A2 HU 9803035 A HU9803035 A HU 9803035A HU P9803035 A HUP9803035 A HU P9803035A HU P9803035 A2 HUP9803035 A2 HU P9803035A2
Authority
HU
Hungary
Prior art keywords
dibromo
bromo
cepham
cephem derivatives
compounds
Prior art date
Application number
HU9803035A
Other languages
English (en)
Inventor
Irena Lukic
Original Assignee
Pliva Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrija Dionicko Drustvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrija Dionicko Drustvo filed Critical Pliva Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrija Dionicko Drustvo
Publication of HU9803035D0 publication Critical patent/HU9803035D0/hu
Publication of HUP9803035A2 publication Critical patent/HUP9803035A2/hu
Publication of HUP9803035A3 publication Critical patent/HUP9803035A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A találmány új, (I), (II) és (III) általánős képletű 7-bróm- és 7,7-dibróm-cef;m és 7-bróm- és 7,7-dibróm-cefém-származékőkra, az ezekelőállítására szőlgáló eljárásra, valamint ezeket tartalmazógyógyszerkészítményekre és állatgyógyászati készítményekre vőnatkőzik.Ezeket a vegyületeket 6,6-dibróm-penicillánsav-szűlfőxidők észtereibőlvagy amidjaiból szerves őldószerekben, tetrabűtil-ammóniűm-brőmidhőzzáadásával vagy anélkül, emelt hőmérsékleten állíthatják elő, és akapőtt vegyületek közül egyeseket ezűtán őxidálják. A találmányszerinti új vegyületek a prőteázők, különösen a hűmán leűkőcitaelasztázők (HLE) pőtenciális inhibitőrai. ŕ
HU9803035A 1997-12-30 1998-12-29 7-bromo- and 7,7-dibromo-cepham and cephem derivatives HUP9803035A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR970713A HRP970713A2 (en) 1997-12-30 1997-12-30 7-bromo- and 7,7 dibromo-cepham and cephem derivatives

Publications (3)

Publication Number Publication Date
HU9803035D0 HU9803035D0 (en) 1999-02-01
HUP9803035A2 true HUP9803035A2 (hu) 1999-09-28
HUP9803035A3 HUP9803035A3 (en) 2001-04-28

Family

ID=10946679

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9803035A HUP9803035A3 (en) 1997-12-30 1998-12-29 7-bromo- and 7,7-dibromo-cepham and cephem derivatives

Country Status (10)

Country Link
EP (1) EP0934944A1 (hu)
JP (1) JPH11255771A (hu)
BG (1) BG103044A (hu)
CA (1) CA2256002A1 (hu)
CZ (1) CZ431098A3 (hu)
HR (1) HRP970713A2 (hu)
HU (1) HUP9803035A3 (hu)
NO (1) NO986185L (hu)
PL (1) PL330590A1 (hu)
SK (1) SK177998A3 (hu)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2337472A1 (de) * 1973-07-24 1975-02-13 Hoechst Ag Alpha-halogenazetidinone und verfahren zu ihrer herstellung
JPH05503290A (ja) * 1989-10-06 1993-06-03 シンファー　ラボラトリーズ，インコーポレーティッド 新規２―スピロシクロプロピルセファロスポリンスルホン誘導体およびそれらの製造法
GB2266526A (en) * 1992-03-17 1993-11-03 Merck & Co Inc Substituted cephalosporin sulfones useful in the treatment of leukemia
GB9513818D0 (en) * 1995-07-06 1995-09-06 Pharmacia Spa 7,7-Disubstituted cephem-4-ketones

Also Published As

Publication number Publication date
HRP970713A2 (en) 1999-10-31
CA2256002A1 (en) 1999-06-30
CZ431098A3 (cs) 1999-07-14
EP0934944A1 (en) 1999-08-11
NO986185L (no) 1999-07-01
NO986185D0 (hu) 1998-12-29
BG103044A (en) 1999-09-30
JPH11255771A (ja) 1999-09-21
HU9803035D0 (en) 1999-02-01
HUP9803035A3 (en) 2001-04-28
SK177998A3 (en) 2000-04-10
PL330590A1 (en) 1999-07-05

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