HUP0600526A2 - Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder - Google Patents

Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder

Info

Publication number
HUP0600526A2
HUP0600526A2 HU0600526A HUP0600526A HUP0600526A2 HU P0600526 A2 HUP0600526 A2 HU P0600526A2 HU 0600526 A HU0600526 A HU 0600526A HU P0600526 A HUP0600526 A HU P0600526A HU P0600526 A2 HUP0600526 A2 HU P0600526A2
Authority
HU
Hungary
Prior art keywords
mania
derivatives
treatment
bipolar disorder
valproenic
Prior art date
Application number
HU0600526A
Other languages
English (en)
Inventor
Mitchell Shirvan
Meir Bialer
Original Assignee
Teva Pharma
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Yissum Res Dev Co filed Critical Teva Pharma
Publication of HUP0600526A2 publication Critical patent/HUP0600526A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU0600526A 2000-07-21 2001-07-20 Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder HUP0600526A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22010200P 2000-07-21 2000-07-21
PCT/US2001/023116 WO2002007677A2 (en) 2000-07-21 2001-07-20 Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder

Publications (1)

Publication Number Publication Date
HUP0600526A2 true HUP0600526A2 (en) 2006-11-28

Family

ID=22822065

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0600526A HUP0600526A2 (en) 2000-07-21 2001-07-20 Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder

Country Status (16)

Country Link
US (2) US6555585B2 (hu)
EP (1) EP1303289A4 (hu)
JP (1) JP2004520263A (hu)
KR (1) KR100843703B1 (hu)
CN (1) CN1251758C (hu)
AU (1) AU2001280699A1 (hu)
CA (1) CA2416821A1 (hu)
CZ (1) CZ2004266A3 (hu)
HU (1) HUP0600526A2 (hu)
IL (1) IL153942A0 (hu)
MX (1) MXPA03000547A (hu)
NO (1) NO20030295D0 (hu)
NZ (1) NZ523917A (hu)
PL (1) PL365588A1 (hu)
WO (1) WO2002007677A2 (hu)
ZA (1) ZA200300641B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1303289A4 (en) * 2000-07-21 2009-08-05 Yissum Res Dev Co USE OF VALPROIC ACID DERIVATIVES AND 2-VALPROENIC ACID AMIDES FOR THE TREATMENT OF MANIE IN CASES OF BIPOLAR DISORDER
AU2003289782A1 (en) * 2002-12-16 2004-07-09 The University Of British Columbia Valproic acid analogues and pharmaceutical compositions thereof
EP1626707A4 (en) * 2003-02-05 2009-07-01 Yissum Res Dev Co CONTINUOUSLY RELEASE FORMULA OF N- (2-PROPYLPENTANOYL) GLYCINAMIDE, AND ASSOCIATED COMPOUNDS
US20040176463A1 (en) * 2003-02-05 2004-09-09 Daniella Licht Immediate release formulation of n-(2-propylpentanoyl)glycinamide
IL157751A0 (en) * 2003-02-28 2004-03-28 Yissum Res Dev Co New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them
IL156203A0 (en) * 2003-05-29 2003-12-23 Yissum Res Dev Co Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders
EP1491188A1 (en) * 2003-06-25 2004-12-29 G2M Cancer Drugs AG Topical use of valproic acid for the prevention or treatment of skin disorders
US20060004098A1 (en) 2003-07-28 2006-01-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds useful for treating neurological disorders
EP1713486A4 (en) * 2003-12-02 2009-04-29 Sheldon Leslie James COMBINED THERAPY FOR THE TREATMENT OF DEMENTIA, DEPRESSION AND APATHY
US20060025477A1 (en) * 2004-07-22 2006-02-02 Artman Linda D Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
WO2007028030A2 (en) * 2005-09-02 2007-03-08 Picobella, Llc Oncogenic regulatory rnas for diagnostics and therapeutics
US7459280B2 (en) * 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
US20080267977A1 (en) * 2007-04-26 2008-10-30 Friedrich-Alexander University Of Erlangen-Nuremberg Combined immunological agent and sensitizing agent for the treatment of cancer
WO2015118537A2 (en) 2014-02-05 2015-08-13 Yeda Research And Development Co. Ltd. Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
MX2019006940A (es) * 2016-12-14 2019-09-06 Sk Biopharmaceuticals Co Ltd Uso de compuestos de carbamato para prevencion, alivio o tratamiento del trastorno bipolar.
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev Combined use of ketamine and bretigabine for the treatment of psychiatric disorders

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU988188A3 (ru) 1973-12-14 1983-01-07 Эсакмадьяросаги Ведьимювек (Инопредприятие) Способ получени N,N-дизамещенных амидов карбоновых кислот
DE3010599A1 (de) 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
US4301176A (en) * 1980-08-18 1981-11-17 Warner-Lambert Company Method of administering calcium valproate
FR2489319A1 (fr) 1980-08-27 1982-03-05 Clin Midy Derives de l'acide amino-4 butyrique et les medicaments, actifs notamment sur le systeme nerveux central, en contenant
BE885303A (fr) 1980-09-19 1981-03-19 Continental Pharma Glycinamides
LU83729A1 (fr) * 1981-11-04 1983-09-01 Galephar Sels d'acide valproique,leur preparation et leur utilisation
FI832935A (fi) 1982-08-20 1984-02-21 Midit Derivat av w-aminosyror, deras framstaellning samt dessa derivat innehaollande blandningar
US4913906B1 (en) 1985-02-28 2000-06-06 Yissum Res Dev Co Controlled release dosage form of valproic acid
IT1190133B (it) 1986-06-19 1988-02-10 Chiesi Farma Spa Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
AU596880B2 (en) 1986-09-17 1990-05-17 Clintec Nutrition Company Liquid nutritional compositions
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
US5585358A (en) * 1993-07-06 1996-12-17 Yissum Research Development Corporation Of The Hebrew University Of Jerusalem Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents
CN1494907A (zh) 1996-03-25 2004-05-12 治疗疼痛的药物组合物
IL121268A0 (en) 1997-07-09 1998-01-04 Dpharm Ltd Branched chain fatty acids their derivatives and use in the treatment of central nervous system disorders
HUP0102456A3 (en) 1998-06-22 2003-07-28 American Biogenetic Sciences The use of valproic acid analog for the treatment and prevention of migraine and affective illness
EP1303289A4 (en) * 2000-07-21 2009-08-05 Yissum Res Dev Co USE OF VALPROIC ACID DERIVATIVES AND 2-VALPROENIC ACID AMIDES FOR THE TREATMENT OF MANIE IN CASES OF BIPOLAR DISORDER

Also Published As

Publication number Publication date
CN1251758C (zh) 2006-04-19
PL365588A1 (en) 2005-01-10
EP1303289A2 (en) 2003-04-23
CA2416821A1 (en) 2002-01-31
KR20030036610A (ko) 2003-05-09
ZA200300641B (en) 2004-01-26
KR100843703B1 (ko) 2008-07-04
EP1303289A4 (en) 2009-08-05
NO20030295L (no) 2003-01-20
CZ2004266A3 (cs) 2005-02-16
WO2002007677A3 (en) 2002-05-30
IL153942A0 (en) 2003-07-31
WO2002007677A2 (en) 2002-01-31
MXPA03000547A (es) 2004-04-05
NO20030295D0 (no) 2003-01-20
AU2001280699A1 (en) 2002-02-05
US6555585B2 (en) 2003-04-29
US20030212142A1 (en) 2003-11-13
US20020103237A1 (en) 2002-08-01
CN1446097A (zh) 2003-10-01
JP2004520263A (ja) 2004-07-08
NZ523917A (en) 2004-11-26

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEB, IL

Free format text: FORMER OWNER(S): TEVA PHARMACEUTICAL INDUSTRIES LTD., IL; YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, IL