HUP0401904A2 - Kardiális perfúzió és vitronectin receptort célzó képalkotó szer egyidejű leképezése - Google Patents

Kardiális perfúzió és vitronectin receptort célzó képalkotó szer egyidejű leképezése

Info

Publication number
HUP0401904A2
HUP0401904A2 HU0401904A HUP0401904A HUP0401904A2 HU P0401904 A2 HUP0401904 A2 HU P0401904A2 HU 0401904 A HU0401904 A HU 0401904A HU P0401904 A HUP0401904 A HU P0401904A HU P0401904 A2 HUP0401904 A2 HU P0401904A2
Authority
HU
Hungary
Prior art keywords
imaging agent
vitronectin receptor
imaging
simultaneous
cardiac perfusion
Prior art date
Application number
HU0401904A
Other languages
English (en)
Inventor
Alan Carpenter
Original Assignee
Bristol-Myers Squibb Pharma Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Pharma Co. filed Critical Bristol-Myers Squibb Pharma Co.
Publication of HUP0401904A2 publication Critical patent/HUP0401904A2/hu
Publication of HUP0401904A3 publication Critical patent/HUP0401904A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acoustics & Sound (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány eljárást ír le egyidejű leképezésre egy emlősben, amelyeljárás a következőkből áll: a) az említett emlősnek beadnak egyvitronectin receptort célzó képalkotó szert és egy perfúziós leképezőszert; és b) egyidejűleg detektálják a vitronectin receptornál kötöttvitronectin receptort célzó képalkotó szert és a perfúziós leképezőszert; és kialakítanak egy képet az említett vitronectint célzóképalkotó szer és az említett perfúzióleképező szer detektálásából. Ó
HU0401904A 2001-08-08 2002-08-07 Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent HUP0401904A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31085901P 2001-08-08 2001-08-08
PCT/US2002/025375 WO2003013346A2 (en) 2001-08-08 2002-08-07 Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent

Publications (2)

Publication Number Publication Date
HUP0401904A2 true HUP0401904A2 (hu) 2004-12-28
HUP0401904A3 HUP0401904A3 (en) 2009-01-28

Family

ID=23204402

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401904A HUP0401904A3 (en) 2001-08-08 2002-08-07 Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent

Country Status (10)

Country Link
US (1) US7138104B2 (hu)
EP (1) EP1423152A4 (hu)
JP (1) JP2004537573A (hu)
CN (1) CN1298390C (hu)
AU (1) AU2002331042B2 (hu)
CA (1) CA2452478A1 (hu)
HU (1) HUP0401904A3 (hu)
MX (1) MXPA04001113A (hu)
NO (1) NO20040555L (hu)
WO (1) WO2003013346A2 (hu)

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HUP0400758A3 (en) * 2000-11-03 2005-02-28 Bristol Myers Squibb Pharma Co Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
JP2005506952A (ja) * 2000-11-27 2005-03-10 ブリストル−マイヤーズ・スクイブ・メディカル・イメージング・インコーポレイテッド 心臓潅流およびビトロネクチンレセプター標的造影剤の同時造影
US6838074B2 (en) * 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
AU2003209392B2 (en) 2002-01-24 2008-10-09 Barnes Jewish Hospital Integrin targeted imaging agents
US6813333B2 (en) * 2002-11-27 2004-11-02 Ge Medical Systems Global Technology Company, Llc Methods and apparatus for detecting structural, perfusion, and functional abnormalities
FR2848750B1 (fr) * 2002-12-13 2007-02-09 Centre Nat Rech Scient Procede d'acquisition de signaux electromagnetiques et produit de contraste pour une telle acquisition
MXPA05012109A (es) * 2003-05-12 2006-02-08 Bristol Myers Squibb Pharma Co Compuestos antagonistas del receptor de vitronectina y su uso en la preparacion de radiofarmaceuticos.
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
EP1940841B9 (fr) * 2005-10-07 2017-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
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EP2721045B1 (en) * 2011-06-20 2017-04-12 Radiomedix Inc. Compositions, methods of synthesis and use of carbohydrate targeted agents
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CN109907856A (zh) * 2017-12-13 2019-06-21 深圳先进技术研究院 超声装置及动物固定装置

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Also Published As

Publication number Publication date
WO2003013346A2 (en) 2003-02-20
EP1423152A4 (en) 2006-12-27
US7138104B2 (en) 2006-11-21
HUP0401904A3 (en) 2009-01-28
NO20040555L (no) 2004-03-23
WO2003013346A3 (en) 2003-08-14
MXPA04001113A (es) 2004-07-08
CA2452478A1 (en) 2003-02-20
CN1298390C (zh) 2007-02-07
JP2004537573A (ja) 2004-12-16
AU2002331042B2 (en) 2007-10-25
EP1423152A2 (en) 2004-06-02
US20030103898A1 (en) 2003-06-05
CN1541115A (zh) 2004-10-27

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