HUP0401818A2 - Eljárás hepatitis vírusfertőzés kezelésére multifázisos interferon felszabadulású profillal - Google Patents
Eljárás hepatitis vírusfertőzés kezelésére multifázisos interferon felszabadulású profillalInfo
- Publication number
- HUP0401818A2 HUP0401818A2 HU0401818A HUP0401818A HUP0401818A2 HU P0401818 A2 HUP0401818 A2 HU P0401818A2 HU 0401818 A HU0401818 A HU 0401818A HU P0401818 A HUP0401818 A HU P0401818A HU P0401818 A2 HUP0401818 A2 HU P0401818A2
- Authority
- HU
- Hungary
- Prior art keywords
- multiphasic
- virus infection
- antiviral agent
- hepatitis virus
- delivery profile
- Prior art date
Links
- 208000006454 hepatitis Diseases 0.000 title abstract 3
- 231100000283 hepatitis Toxicity 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000009385 viral infection Effects 0.000 title abstract 2
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 239000003443 antiviral agent Substances 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Abstract
A találmány tárgya hepatitis vírusfertőzés kezelésére vonatkozik. Azeljárások általában egy antivirális szert tartalmazó készítményadagolását foglalják magukban olyan adagolási módban, amellyel aszérumban az antivirális szer multifázisos koncentrációprofiljavalósítható meg. Ez az adagolási mód kevésbé gyakori adagolásieseményt foglal magában, mint a napjainkban elérhetőhepatitisterápiák. A találmány szerinti eljárások alkalmazásával elértantivirális szer multifázisos szérumkoncentráció profilja kezdetigyors vírustiter-csökkenést; majd ezt követően a vírustiter továbbicsökkenését idézi elő, és így hosszan tartó vírusválasz alakul ki. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32774401P | 2001-10-05 | 2001-10-05 | |
PCT/US2002/030837 WO2003030923A1 (en) | 2001-10-05 | 2002-09-26 | Method of treating hepatitis virus infection with a multiphasic interferon delivery profile |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0401818A2 true HUP0401818A2 (hu) | 2004-11-29 |
Family
ID=23277854
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0401818A HUP0401818A2 (hu) | 2001-10-05 | 2002-09-26 | Eljárás hepatitis vírusfertőzés kezelésére multifázisos interferon felszabadulású profillal |
Country Status (15)
Country | Link |
---|---|
US (2) | US20050063949A1 (hu) |
EP (1) | EP1450838A4 (hu) |
JP (1) | JP2005508943A (hu) |
KR (1) | KR20050030886A (hu) |
CN (1) | CN1738635A (hu) |
AR (1) | AR036728A1 (hu) |
BR (1) | BR0213103A (hu) |
CA (1) | CA2460690A1 (hu) |
HU (1) | HUP0401818A2 (hu) |
IL (1) | IL160965A0 (hu) |
MX (1) | MXPA04003238A (hu) |
NO (1) | NO20041814L (hu) |
PL (1) | PL369870A1 (hu) |
WO (1) | WO2003030923A1 (hu) |
ZA (1) | ZA200402236B (hu) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002225870B2 (en) | 2000-11-03 | 2006-09-21 | Intarcia Therapeutics, Inc. | Method for short-term and long-term drug dosimetry |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
EP1561470A1 (en) * | 2003-06-20 | 2005-08-10 | Innogenetics N.V. | HCV vaccines comprising the envelope-1 (E1) protein or the corresponding DNA and at least one antiviral agent |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
DE602007009377D1 (de) | 2006-05-30 | 2010-11-04 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
KR101200728B1 (ko) | 2006-08-09 | 2012-11-13 | 인타르시아 세라퓨틱스 인코포레이티드 | 삼투성 전달 시스템 및 피스톤 조립체 |
AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
AU2008244523B2 (en) | 2007-04-23 | 2012-02-16 | Intarcia Therapeutics, Inc. | Suspension formulations of insulinotropic peptides and uses thereof |
US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
JP5323832B2 (ja) | 2007-08-07 | 2013-10-23 | アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー | 酸性水溶液中にgdf−5を含むタンパク質製剤 |
EP2240155B1 (en) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Devices, formulations, and methods for delivery of multiple beneficial agents |
WO2009120991A2 (en) * | 2008-03-27 | 2009-10-01 | Medtronic, Inc. | Pharmacokinetic and pharmacodynamic tools to define patient specific therapeutic regimens |
US20090246171A1 (en) * | 2008-03-27 | 2009-10-01 | Van Antwerp William P | Automatic system for dose control in treating hepatitis c using infusion pumps |
CA2720845A1 (en) | 2008-04-14 | 2009-10-22 | Advanced Technologies And Regenerative Medicine, Llc | Liquid buffered gdf-5 formulations |
US9561214B2 (en) * | 2008-10-16 | 2017-02-07 | Array Biopharma Inc. | Method of treatment using inhibitors of mitosis |
WO2011014882A1 (en) | 2009-07-31 | 2011-02-03 | Medtronic, Inc. | CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS |
SI2462246T1 (en) | 2009-09-28 | 2018-01-31 | Intarcia Therapeutics, Inc. | Fast-setting and / or cessation of substantially unchanged delivery of the product |
WO2011159930A2 (en) | 2010-06-16 | 2011-12-22 | Medtronic, Inc. | Damping systems for stabilizing medications in drug delivery devices |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
GB2515942A (en) | 2011-10-21 | 2015-01-07 | Abbvie Inc | Combination treatment (e.g. with ABT-072 or ABT-333) of DAAs for use in treating HCV |
US8853176B2 (en) | 2011-10-21 | 2014-10-07 | Abbvie Inc. | Methods for treating HCV |
CN103071147A (zh) * | 2011-10-26 | 2013-05-01 | 麦德托尼克公司 | 干扰素-α向乙型肝炎感染的患者的连续皮下施用 |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
KR20240042548A (ko) | 2015-06-03 | 2024-04-02 | 인타르시아 세라퓨틱스 인코포레이티드 | 임플란트 배치 및 제거 시스템들 |
WO2017189978A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
MA53353A (fr) | 2016-05-16 | 2021-06-09 | Intarcia Therapeutics Inc | Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
EP3565580B1 (en) | 2017-01-03 | 2024-03-06 | i2o Therapeutics, Inc. | Continuous administration of exenatide and co-adminstration of acetaminophen, ethinylestradiol or levonorgestrel |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5372808A (en) * | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
US5908621A (en) * | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
US5980884A (en) * | 1996-02-05 | 1999-11-09 | Amgen, Inc. | Methods for retreatment of patients afflicted with Hepatitis C using consensus interferon |
US6172046B1 (en) * | 1997-09-21 | 2001-01-09 | Schering Corporation | Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection |
US6455051B1 (en) * | 1997-10-13 | 2002-09-24 | Otsuka Pharmaceutical Co., Ltd. | Ameliorant for hepatitis C therapeutic effect and application thereof |
US6824768B2 (en) * | 1998-12-18 | 2004-11-30 | Schering Corporation | Ribavirin-pegylated interferon alfa induction HCV combination therapy |
US6245740B1 (en) * | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
AU2002225870B2 (en) * | 2000-11-03 | 2006-09-21 | Intarcia Therapeutics, Inc. | Method for short-term and long-term drug dosimetry |
-
2002
- 2002-09-26 MX MXPA04003238A patent/MXPA04003238A/es not_active Application Discontinuation
- 2002-09-26 JP JP2003533954A patent/JP2005508943A/ja active Pending
- 2002-09-26 HU HU0401818A patent/HUP0401818A2/hu unknown
- 2002-09-26 CN CNA028233530A patent/CN1738635A/zh active Pending
- 2002-09-26 EP EP02763766A patent/EP1450838A4/en not_active Withdrawn
- 2002-09-26 KR KR1020047005042A patent/KR20050030886A/ko not_active Application Discontinuation
- 2002-09-26 CA CA002460690A patent/CA2460690A1/en not_active Abandoned
- 2002-09-26 IL IL16096502A patent/IL160965A0/xx unknown
- 2002-09-26 BR BR0213103-0A patent/BR0213103A/pt not_active IP Right Cessation
- 2002-09-26 US US10/490,458 patent/US20050063949A1/en not_active Abandoned
- 2002-09-26 PL PL02369870A patent/PL369870A1/xx not_active Application Discontinuation
- 2002-09-26 WO PCT/US2002/030837 patent/WO2003030923A1/en active Application Filing
- 2002-10-03 AR ARP020103740A patent/AR036728A1/es unknown
-
2004
- 2004-03-19 ZA ZA200402236A patent/ZA200402236B/en unknown
- 2004-05-04 NO NO20041814A patent/NO20041814L/no not_active Application Discontinuation
-
2009
- 2009-04-08 US US12/420,573 patent/US20090196853A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ZA200402236B (en) | 2005-03-22 |
KR20050030886A (ko) | 2005-03-31 |
JP2005508943A (ja) | 2005-04-07 |
MXPA04003238A (es) | 2004-07-08 |
WO2003030923A1 (en) | 2003-04-17 |
EP1450838A4 (en) | 2005-09-28 |
BR0213103A (pt) | 2004-09-21 |
US20050063949A1 (en) | 2005-03-24 |
CN1738635A (zh) | 2006-02-22 |
AR036728A1 (es) | 2004-09-29 |
CA2460690A1 (en) | 2003-04-17 |
EP1450838A1 (en) | 2004-09-01 |
NO20041814L (no) | 2004-06-11 |
US20090196853A1 (en) | 2009-08-06 |
PL369870A1 (en) | 2005-05-02 |
IL160965A0 (en) | 2004-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |