HUP0401522A2 - New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation - Google Patents

New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation

Info

Publication number
HUP0401522A2
HUP0401522A2 HU0401522A HUP0401522A HUP0401522A2 HU P0401522 A2 HUP0401522 A2 HU P0401522A2 HU 0401522 A HU0401522 A HU 0401522A HU P0401522 A HUP0401522 A HU P0401522A HU P0401522 A2 HUP0401522 A2 HU P0401522A2
Authority
HU
Hungary
Prior art keywords
oxo
general formula
benzylidene
piperidin
acetamide
Prior art date
Application number
HU0401522A
Other languages
English (en)
Hungarian (hu)
Inventor
Istvan Borza
Csilla Horvath
Sandor Dr Farkas
Istvan Dr Gyertyan
Jozsef Dr Nagy
Sandor Kolok
Kornel Dr Galgoczy
Katalin Dr Saghy
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU0401522A priority Critical patent/HUP0401522A2/hu
Publication of HU0401522D0 publication Critical patent/HU0401522D0/hu
Priority to UAA200702171A priority patent/UA87862C2/ru
Priority to ES05763197T priority patent/ES2302214T3/es
Priority to JP2007523160A priority patent/JP4814880B2/ja
Priority to AT05763197T priority patent/ATE387440T1/de
Priority to EA200700367A priority patent/EA011241B1/ru
Priority to PL05763197T priority patent/PL1773810T3/pl
Priority to CA002574148A priority patent/CA2574148A1/en
Priority to HK07111209.7A priority patent/HK1105966B/en
Priority to BRPI0513902-3A priority patent/BRPI0513902A/pt
Priority to RSP-2008/0123A priority patent/RS50573B/sr
Priority to EP05763197A priority patent/EP1773810B1/en
Priority to PCT/HU2005/000077 priority patent/WO2006010964A1/en
Priority to SI200530213T priority patent/SI1773810T1/sl
Priority to NZ552137A priority patent/NZ552137A/xx
Priority to MX2007001055A priority patent/MX2007001055A/es
Priority to CNA2005800243746A priority patent/CN1989128A/zh
Priority to AP2006003839A priority patent/AP2074A/en
Priority to GEAP20059892A priority patent/GEP20084492B/en
Priority to PT05763197T priority patent/PT1773810E/pt
Priority to AU2005266159A priority patent/AU2005266159B2/en
Priority to HR20080127T priority patent/HRP20080127T3/xx
Priority to DE602005005064T priority patent/DE602005005064T2/de
Priority to US11/658,789 priority patent/US8008326B2/en
Priority to KR1020077000262A priority patent/KR20070058428A/ko
Priority to DK05763197T priority patent/DK1773810T3/da
Publication of HUP0401522A2 publication Critical patent/HUP0401522A2/hu
Priority to IL179484A priority patent/IL179484A0/en
Priority to ZA200700320A priority patent/ZA200700320B/en
Priority to TNP2007000018A priority patent/TNSN07018A1/en
Priority to MA29703A priority patent/MA28816B1/fr
Priority to NO20071108A priority patent/NO20071108L/no
Priority to CY20081100349T priority patent/CY1107368T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0401522A 2004-07-29 2004-07-29 New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation HUP0401522A2 (en)

Priority Applications (32)

Application Number Priority Date Filing Date Title
HU0401522A HUP0401522A2 (en) 2004-07-29 2004-07-29 New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation
DK05763197T DK1773810T3 (da) 2004-07-29 2005-07-21 Hidtil ukendte 4-benzylidenpiperidinderivater
NZ552137A NZ552137A (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
MX2007001055A MX2007001055A (es) 2004-07-29 2005-07-21 Nuevos derivados de 4-bencilidenpiperidina.
JP2007523160A JP4814880B2 (ja) 2004-07-29 2005-07-21 新規な４−ベンジリデン−ピペリジン誘導体
AT05763197T ATE387440T1 (de) 2004-07-29 2005-07-21 Neue 4-benzylidenpiperidinderivate
EA200700367A EA011241B1 (ru) 2004-07-29 2005-07-21 Новые производные 4-бензилиденпиперидина
PL05763197T PL1773810T3 (pl) 2004-07-29 2005-07-21 Nowe pochodne 4-benzylidenopiperydyny
CA002574148A CA2574148A1 (en) 2004-07-29 2005-07-21 4-benzylidene-piperidine derivatives
HK07111209.7A HK1105966B (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
AP2006003839A AP2074A (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
RSP-2008/0123A RS50573B (sr) 2004-07-29 2005-07-21 Novi derivati 4-benziliden-piperidina
EP05763197A EP1773810B1 (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
PCT/HU2005/000077 WO2006010964A1 (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
SI200530213T SI1773810T1 (sl) 2004-07-29 2005-07-21 Novi 4-benziliden-piperidinski derivati
UAA200702171A UA87862C2 (en) 2004-07-29 2005-07-21 4-benzylidene-piperidin derivatives
CNA2005800243746A CN1989128A (zh) 2004-07-29 2005-07-21 新的4－苯亚甲基－哌啶衍生物
GEAP20059892A GEP20084492B (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
BRPI0513902-3A BRPI0513902A (pt) 2004-07-29 2005-07-21 novos derivados de 4-benzilideno-piperidina
ES05763197T ES2302214T3 (es) 2004-07-29 2005-07-21 Nuevos derivados de 4-bencilidenpiperidina.
PT05763197T PT1773810E (pt) 2004-07-29 2005-07-21 Novos derivados 4-benzilidenopiperidina
AU2005266159A AU2005266159B2 (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives
HR20080127T HRP20080127T3 (hr) 2004-07-29 2005-07-21 Novi derivati 4-benziliden-piperidina
DE602005005064T DE602005005064T2 (de) 2004-07-29 2005-07-21 Neue 4-benzylidenpiperidinderivate
US11/658,789 US8008326B2 (en) 2004-07-29 2005-07-21 4-benzyledene-piperidin derivatives
KR1020077000262A KR20070058428A (ko) 2004-07-29 2005-07-21 신규 4-벤질리덴-피페리딘 유도체
IL179484A IL179484A0 (en) 2004-07-29 2006-11-22 New 4-benzylidene-piperidin derivatives
ZA200700320A ZA200700320B (en) 2004-07-29 2007-01-11 New 4-benzylidene-piperidin derivatives
TNP2007000018A TNSN07018A1 (en) 2004-07-29 2007-01-17 New 4-benzylidene-piperidin derivatives
MA29703A MA28816B1 (fr) 2004-07-29 2007-02-22 Nouveaux derives de 4-benzylidene-piperidine
NO20071108A NO20071108L (no) 2004-07-29 2007-02-27 Nye 4-benzylidenpiperidinderivater
CY20081100349T CY1107368T1 (el) 2004-07-29 2008-03-27 Νεα παραγωγα 4-βενζυλιδενο-πιπεριδινης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0401522A HUP0401522A2 (en) 2004-07-29 2004-07-29 New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation

Publications (2)

Publication Number Publication Date
HU0401522D0 HU0401522D0 (en) 2004-09-28
HUP0401522A2 true HUP0401522A2 (en) 2006-04-28

Family

ID=89985407

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401522A HUP0401522A2 (en) 2004-07-29 2004-07-29 New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation

Country Status (31)

Country Link
US (1) US8008326B2 (enExample)
EP (1) EP1773810B1 (enExample)
JP (1) JP4814880B2 (enExample)
KR (1) KR20070058428A (enExample)
CN (1) CN1989128A (enExample)
AP (1) AP2074A (enExample)
AT (1) ATE387440T1 (enExample)
AU (1) AU2005266159B2 (enExample)
BR (1) BRPI0513902A (enExample)
CA (1) CA2574148A1 (enExample)
CY (1) CY1107368T1 (enExample)
DE (1) DE602005005064T2 (enExample)
DK (1) DK1773810T3 (enExample)
EA (1) EA011241B1 (enExample)
ES (1) ES2302214T3 (enExample)
GE (1) GEP20084492B (enExample)
HR (1) HRP20080127T3 (enExample)
HU (1) HUP0401522A2 (enExample)
IL (1) IL179484A0 (enExample)
MA (1) MA28816B1 (enExample)
MX (1) MX2007001055A (enExample)
NO (1) NO20071108L (enExample)
NZ (1) NZ552137A (enExample)
PL (1) PL1773810T3 (enExample)
PT (1) PT1773810E (enExample)
RS (1) RS50573B (enExample)
SI (1) SI1773810T1 (enExample)
TN (1) TNSN07018A1 (enExample)
UA (1) UA87862C2 (enExample)
WO (1) WO2006010964A1 (enExample)
ZA (1) ZA200700320B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2520567A3 (en) 2006-02-23 2012-12-12 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group
CN101426381A (zh) * 2006-04-21 2009-05-06 西诺米克斯公司 含有高效鲜味调料的可食用组合物及其制备方法
ES2347192T3 (es) * 2006-06-08 2010-10-26 Bristol-Myers Squibb Company Derivados de alqueno piperidina como agentes antivirales.
EA201170007A1 (ru) * 2008-07-08 2011-08-30 Рихтер Гедеон Нирт. Новая кристаллическая форма 2-[4-(4-фторбензил)пиперидин-1-ил]-2-оксо-n-(2-оксо-2,3-дигидробензоксазол-6-ил)ацетамида
KR20120123089A (ko) 2010-02-16 2012-11-07 화이자 인코포레이티드 5-ＨＴ₄ 수용체의 부분 효능제인 (Ｒ)-4-((4-((4-(테트라히드로푸란-3-일옥시)벤조［ｄ］이속사졸-3-일옥시)메틸)피페리딘-1-일)메틸)테트라히드로-2Ｈ-피란-4-올
EP2615084B1 (en) 2010-09-07 2016-01-06 Taiho Pharmaceutical Co., Ltd. Prostaglandin d synthase inhibitory piperidine compounds
US20120322824A1 (en) * 2011-01-04 2012-12-20 Surratt Christopher K Cocaine Antagonist/Antidepressant Pharmaceutical Preparations
AU2013251079B2 (en) 2012-04-20 2017-03-23 Ucb Pharma S.A. Methods for treating Parkinson's disease
MX381417B (es) 2014-08-28 2025-03-12 Asceneuron Sa Inhibidores de glucosidasa.
WO2017106254A1 (en) * 2015-12-18 2017-06-22 Merck Sharp & Dohme Corp. Glycosidase inhibitors and uses thereof
US11261183B2 (en) 2016-02-25 2022-03-01 Asceneuron Sa Sulfoximine glycosidase inhibitors
CN108884077A (zh) 2016-02-25 2018-11-23 阿森纽荣股份公司 糖苷酶抑制剂
JP2019506430A (ja) 2016-02-25 2019-03-07 エースニューロン・ソシエテ・アノニム グリコシダーゼ阻害剤
JP6971999B2 (ja) 2016-02-25 2021-11-24 エースニューロン・ソシエテ・アノニム ピペラジン誘導体の酸付加塩
US9486444B1 (en) 2016-03-21 2016-11-08 King Saud University Anti-cancer compound
US11213525B2 (en) 2017-08-24 2022-01-04 Asceneuron Sa Linear glycosidase inhibitors
US11795165B2 (en) 2018-08-22 2023-10-24 Asceneuron Sa Tetrahydro-benzoazepine glycosidase inhibitors
WO2020039029A1 (en) 2018-08-22 2020-02-27 Asceneuron S. A. Spiro compounds as glycosidase inhibitors
CA3110032A1 (en) 2018-08-22 2020-02-27 Asceneuron S.A. Succinate and fumarate acid addition salts of piperazine derivatives
US12016852B2 (en) 2018-08-22 2024-06-25 Asceneuron Sa Pyrrolidine glycosidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
TW498067B (en) * 1996-07-19 2002-08-11 Hoffmann La Roche 4-hydroxy-piperidine derivatives
CA2220649C (en) 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
KR100890676B1 (ko) 2001-07-24 2009-03-26 리히데 게데온 베기에스제티 기아르 알티 신규한 카르복시산 아미드 화합물

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MA28816B1 (fr) 2007-08-01
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AP2006003839A0 (en) 2006-12-31
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