HRP20080127T3 - Novi derivati 4-benziliden-piperidina - Google Patents

Novi derivati 4-benziliden-piperidina

Info

Publication number
HRP20080127T3
HRP20080127T3 HR20080127T HRP20080127T HRP20080127T3 HR P20080127 T3 HRP20080127 T3 HR P20080127T3 HR 20080127 T HR20080127 T HR 20080127T HR P20080127 T HRP20080127 T HR P20080127T HR P20080127 T3 HRP20080127 T3 HR P20080127T3
Authority
HR
Croatia
Prior art keywords
optionally substituted
halogen atom
oxo
thioxo
amino
Prior art date
Application number
HR20080127T
Other languages
English (en)
Croatian (hr)
Inventor
Borza Istv�n
Horv�th Csilla
Farkas S�ndor
Gyerty�n Istv�n
Nagy J�zsef
Kolok S�ndor
Galg�czy Korn�l
S�ghy Katalin
Original Assignee
Richter Gedeon Vegy�szeti Gy�r RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegy�szeti Gy�r RT filed Critical Richter Gedeon Vegy�szeti Gy�r RT
Publication of HRP20080127T3 publication Critical patent/HRP20080127T3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20080127T 2004-07-29 2005-07-21 Novi derivati 4-benziliden-piperidina HRP20080127T3 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0401522A HUP0401522A2 (en) 2004-07-29 2004-07-29 New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation
PCT/HU2005/000077 WO2006010964A1 (en) 2004-07-29 2005-07-21 New 4-benzylidene-piperidin derivatives

Publications (1)

Publication Number Publication Date
HRP20080127T3 true HRP20080127T3 (hr) 2008-04-30

Family

ID=89985407

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20080127T HRP20080127T3 (hr) 2004-07-29 2005-07-21 Novi derivati 4-benziliden-piperidina

Country Status (31)

Country Link
US (1) US8008326B2 (enExample)
EP (1) EP1773810B1 (enExample)
JP (1) JP4814880B2 (enExample)
KR (1) KR20070058428A (enExample)
CN (1) CN1989128A (enExample)
AP (1) AP2074A (enExample)
AT (1) ATE387440T1 (enExample)
AU (1) AU2005266159B2 (enExample)
BR (1) BRPI0513902A (enExample)
CA (1) CA2574148A1 (enExample)
CY (1) CY1107368T1 (enExample)
DE (1) DE602005005064T2 (enExample)
DK (1) DK1773810T3 (enExample)
EA (1) EA011241B1 (enExample)
ES (1) ES2302214T3 (enExample)
GE (1) GEP20084492B (enExample)
HR (1) HRP20080127T3 (enExample)
HU (1) HUP0401522A2 (enExample)
IL (1) IL179484A0 (enExample)
MA (1) MA28816B1 (enExample)
MX (1) MX2007001055A (enExample)
NO (1) NO20071108L (enExample)
NZ (1) NZ552137A (enExample)
PL (1) PL1773810T3 (enExample)
PT (1) PT1773810E (enExample)
RS (1) RS50573B (enExample)
SI (1) SI1773810T1 (enExample)
TN (1) TNSN07018A1 (enExample)
UA (1) UA87862C2 (enExample)
WO (1) WO2006010964A1 (enExample)
ZA (1) ZA200700320B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2520567A3 (en) 2006-02-23 2012-12-12 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group
CN101426381A (zh) * 2006-04-21 2009-05-06 西诺米克斯公司 含有高效鲜味调料的可食用组合物及其制备方法
ES2347192T3 (es) * 2006-06-08 2010-10-26 Bristol-Myers Squibb Company Derivados de alqueno piperidina como agentes antivirales.
EA201170007A1 (ru) * 2008-07-08 2011-08-30 Рихтер Гедеон Нирт. Новая кристаллическая форма 2-[4-(4-фторбензил)пиперидин-1-ил]-2-оксо-n-(2-оксо-2,3-дигидробензоксазол-6-ил)ацетамида
KR20120123089A (ko) 2010-02-16 2012-11-07 화이자 인코포레이티드 5-HT₄ 수용체의 부분 효능제인 (R)-4-((4-((4-(테트라히드로푸란-3-일옥시)벤조[d]이속사졸-3-일옥시)메틸)피페리딘-1-일)메틸)테트라히드로-2H-피란-4-올
EP2615084B1 (en) 2010-09-07 2016-01-06 Taiho Pharmaceutical Co., Ltd. Prostaglandin d synthase inhibitory piperidine compounds
US20120322824A1 (en) * 2011-01-04 2012-12-20 Surratt Christopher K Cocaine Antagonist/Antidepressant Pharmaceutical Preparations
AU2013251079B2 (en) 2012-04-20 2017-03-23 Ucb Pharma S.A. Methods for treating Parkinson's disease
MX381417B (es) 2014-08-28 2025-03-12 Asceneuron Sa Inhibidores de glucosidasa.
WO2017106254A1 (en) * 2015-12-18 2017-06-22 Merck Sharp & Dohme Corp. Glycosidase inhibitors and uses thereof
US11261183B2 (en) 2016-02-25 2022-03-01 Asceneuron Sa Sulfoximine glycosidase inhibitors
CN108884077A (zh) 2016-02-25 2018-11-23 阿森纽荣股份公司 糖苷酶抑制剂
JP2019506430A (ja) 2016-02-25 2019-03-07 エースニューロン・ソシエテ・アノニム グリコシダーゼ阻害剤
JP6971999B2 (ja) 2016-02-25 2021-11-24 エースニューロン・ソシエテ・アノニム ピペラジン誘導体の酸付加塩
US9486444B1 (en) 2016-03-21 2016-11-08 King Saud University Anti-cancer compound
US11213525B2 (en) 2017-08-24 2022-01-04 Asceneuron Sa Linear glycosidase inhibitors
US11795165B2 (en) 2018-08-22 2023-10-24 Asceneuron Sa Tetrahydro-benzoazepine glycosidase inhibitors
WO2020039029A1 (en) 2018-08-22 2020-02-27 Asceneuron S. A. Spiro compounds as glycosidase inhibitors
CA3110032A1 (en) 2018-08-22 2020-02-27 Asceneuron S.A. Succinate and fumarate acid addition salts of piperazine derivatives
US12016852B2 (en) 2018-08-22 2024-06-25 Asceneuron Sa Pyrrolidine glycosidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9610738B (en) * 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
TW498067B (en) * 1996-07-19 2002-08-11 Hoffmann La Roche 4-hydroxy-piperidine derivatives
CA2220649C (en) 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
KR100890676B1 (ko) 2001-07-24 2009-03-26 리히데 게데온 베기에스제티 기아르 알티 신규한 카르복시산 아미드 화합물

Also Published As

Publication number Publication date
JP2008508247A (ja) 2008-03-21
CA2574148A1 (en) 2006-02-02
AU2005266159B2 (en) 2011-09-29
EP1773810B1 (en) 2008-02-27
MA28816B1 (fr) 2007-08-01
KR20070058428A (ko) 2007-06-08
NZ552137A (en) 2009-08-28
BRPI0513902A (pt) 2008-05-20
HU0401522D0 (en) 2004-09-28
AP2006003839A0 (en) 2006-12-31
HK1105966A1 (en) 2008-02-29
HUP0401522A2 (en) 2006-04-28
IL179484A0 (en) 2007-05-15
DE602005005064D1 (de) 2008-04-10
ATE387440T1 (de) 2008-03-15
EA200700367A1 (ru) 2007-06-29
DE602005005064T2 (de) 2009-02-26
SI1773810T1 (sl) 2008-06-30
CN1989128A (zh) 2007-06-27
MX2007001055A (es) 2007-04-16
US8008326B2 (en) 2011-08-30
JP4814880B2 (ja) 2011-11-16
EP1773810A1 (en) 2007-04-18
WO2006010964A1 (en) 2006-02-02
DK1773810T3 (da) 2008-06-23
PT1773810E (pt) 2008-04-09
ES2302214T3 (es) 2008-07-01
PL1773810T3 (pl) 2008-07-31
AP2074A (en) 2009-12-14
NO20071108L (no) 2007-02-27
GEP20084492B (en) 2008-09-25
RS50573B (sr) 2010-05-07
EA011241B1 (ru) 2009-02-27
UA87862C2 (en) 2009-08-25
US20080312222A1 (en) 2008-12-18
AU2005266159A1 (en) 2006-02-02
TNSN07018A1 (en) 2008-06-02
ZA200700320B (en) 2008-05-28
CY1107368T1 (el) 2012-12-19

Similar Documents

Publication Publication Date Title
CO5560570A2 (es) Nuevos compuestos de amida de acido carboxilico y procedimiento para la sintesis de los mismos
TNSN07018A1 (en) New 4-benzylidene-piperidin derivatives
CO6290646A2 (es) Derivados de oxadiazol activos sobre fosfato de esfingosina-1
ES2571028T3 (es) Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso
HRP20040429B1 (hr) Derivati sulfonamida, njihova priprema i upotrebakao lijekova
PE20060525A1 (es) Compuestos heterociclicos como inhibidores de cetp
AR069961A1 (es) Derivados de (aza)indol sustituidos en la posicion 5 utiles en el tratamiento de la inflamacion y el dolor, composiciones farmaceuticas que los comprenden, proceso de preparacion de los mismos y compuestos intermediarios.
AR043195A1 (es) Inhibidores no nucleosidos de la transcriptasa inversa derivados de pirazol
EA201071113A1 (ru) ПОЛИЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ 2-ГЕТЕРОАРИЛ-6-ФЕНИЛИМИДАЗО[1,2-α] ПИРИДИНОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ
WO2008088692A3 (en) Spirochromanon derivatives
EP1535910A4 (en) CHINOLINE DERIVATIVES AND CHINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORILATION OF THE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR
PE20081447A1 (es) Compuestos y composiciones como inhibidores de la proteina cinasa
NO20005881D0 (no) Heterocykliske forbindelser og metoder for å behandle kardialsvikt og andre sykdommer
NZ763248A (en) Cap-dependent endonuclease inhibitors
PE20081378A1 (es) Derivados de 1,2,4-triazol como moduladores de mglur5
PE20020352A1 (es) Imidazoles sustituidos como inhibidores carboxipeptidasa
AR051767A1 (es) Derivados de quinolina e isoquinolina 5-sustituidos un procedimiento para su preparacion y su uso como inhibidores de la inflamacion
ATE554147T1 (de) Neue organische fluoreszierende sulfonylharnstoff-benzoxazinon-pigmente
AR008372A1 (es) Compuestos de benzoxazinona que son antagonistas de receptores de dopamina 4, metodo para tratar psicosis y ezquizofrenia utilizando dichos compuestos ycomposicion que los contiene
HRP20030610B1 (en) Process for the preparation of mesylates of piperazine derivatives
PE20071324A1 (es) Metodos de usar derivados de 3-piridilo como pesticidas
AR074915A1 (es) Derivados de 2-piridin-2-il-pirazol-3(2h)-ona, composiciones farmaceuticas que los comprenden y uso de los mismos para el tratamiento de trastornos del aparato cardiovascular, glaucoma y otras patologias.
NO20071110L (no) Nye benzoylureaderivater
DE60107056D1 (de) Benzoxazolderivate als tnf und pde iv inhibitoren
EA200801536A1 (ru) Новые тиенопирсульфоновые производные