UA87862C2 - 4-benzylidene-piperidin derivatives - Google Patents
4-benzylidene-piperidin derivativesInfo
- Publication number
- UA87862C2 UA87862C2 UAA200702171A UAA200702171A UA87862C2 UA 87862 C2 UA87862 C2 UA 87862C2 UA A200702171 A UAA200702171 A UA A200702171A UA A200702171 A UAA200702171 A UA A200702171A UA 87862 C2 UA87862 C2 UA 87862C2
- Authority
- UA
- Ukraine
- Prior art keywords
- benzylidene
- piperidin derivatives
- piperidin
- derivatives
- analgesica
- Prior art date
Links
- QMQNIKYRPSFQKB-UHFFFAOYSA-N 4-benzylidenepiperidine Chemical class C1CNCCC1=CC1=CC=CC=C1 QMQNIKYRPSFQKB-UHFFFAOYSA-N 0.000 title abstract 2
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 1
- 102000034527 Retinoid X Receptors Human genes 0.000 abstract 1
- 108010038912 Retinoid X Receptors Proteins 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Psychology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to new 4-benzylidene-piperidin derivatives of formula (I), useful as NMDA, in a particular NR2B subunit containing receptor antagonists and analgesica.(I)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0401522A HUP0401522A2 (en) | 2004-07-29 | 2004-07-29 | New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA87862C2 true UA87862C2 (en) | 2009-08-25 |
Family
ID=89985407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200702171A UA87862C2 (en) | 2004-07-29 | 2005-07-21 | 4-benzylidene-piperidin derivatives |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US8008326B2 (en) |
| EP (1) | EP1773810B1 (en) |
| JP (1) | JP4814880B2 (en) |
| KR (1) | KR20070058428A (en) |
| CN (1) | CN1989128A (en) |
| AP (1) | AP2074A (en) |
| AT (1) | ATE387440T1 (en) |
| AU (1) | AU2005266159B2 (en) |
| BR (1) | BRPI0513902A (en) |
| CA (1) | CA2574148A1 (en) |
| CY (1) | CY1107368T1 (en) |
| DE (1) | DE602005005064T2 (en) |
| DK (1) | DK1773810T3 (en) |
| EA (1) | EA011241B1 (en) |
| ES (1) | ES2302214T3 (en) |
| GE (1) | GEP20084492B (en) |
| HK (1) | HK1105966A1 (en) |
| HR (1) | HRP20080127T3 (en) |
| HU (1) | HUP0401522A2 (en) |
| IL (1) | IL179484A0 (en) |
| MA (1) | MA28816B1 (en) |
| MX (1) | MX2007001055A (en) |
| NO (1) | NO20071108L (en) |
| NZ (1) | NZ552137A (en) |
| PL (1) | PL1773810T3 (en) |
| PT (1) | PT1773810E (en) |
| RS (1) | RS50573B (en) |
| SI (1) | SI1773810T1 (en) |
| TN (1) | TNSN07018A1 (en) |
| UA (1) | UA87862C2 (en) |
| WO (1) | WO2006010964A1 (en) |
| ZA (1) | ZA200700320B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007099828A1 (en) | 2006-02-23 | 2007-09-07 | Shionogi & Co., Ltd. | Nirogenous heterocyclic derivatives substituted with cyclic groups |
| CN101426381A (en) * | 2006-04-21 | 2009-05-06 | 西诺米克斯公司 | Comestible compositions comprising high potency savory flavorants, and processes for producing them |
| ES2347192T3 (en) * | 2006-06-08 | 2010-10-26 | Bristol-Myers Squibb Company | DERIVATIVES OF PIPERIDINE ALKEN AS ANTIVIRAL AGENTS. |
| AU2009268631A1 (en) * | 2008-07-08 | 2010-01-14 | Richter Gedeon Nyrt | Novel crystalline form of 2-[4(4-fluoro-benzyl)-piperidine-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide |
| IN2012DN06631A (en) | 2010-02-16 | 2015-10-23 | Pfizer | |
| JP5693591B2 (en) | 2010-09-07 | 2015-04-01 | 大鵬薬品工業株式会社 | Piperidine compounds that inhibit prostaglandin D synthase |
| US20120322824A1 (en) * | 2011-01-04 | 2012-12-20 | Surratt Christopher K | Cocaine Antagonist/Antidepressant Pharmaceutical Preparations |
| EP2838530B1 (en) | 2012-04-20 | 2017-04-05 | UCB Biopharma SPRL | Methods for treating parkinson's disease |
| EP3868752A1 (en) | 2014-08-28 | 2021-08-25 | Asceneuron SA | Glycosidase inhibitors |
| EP3389658B1 (en) | 2015-12-18 | 2020-11-25 | Merck Sharp & Dohme Corp. | Glycosidase inhibitors and uses thereof |
| MA43677A (en) | 2016-02-25 | 2018-11-28 | Asceneuron Sa | GLYCOSIDASE INHIBITORS |
| US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
| CN109071526B (en) | 2016-02-25 | 2023-02-28 | 阿森纽荣股份公司 | Acid addition salts of piperazine derivatives |
| EP3419972B1 (en) | 2016-02-25 | 2023-07-26 | Asceneuron SA | Glycosidase inhibitors |
| US9486444B1 (en) | 2016-03-21 | 2016-11-08 | King Saud University | Anti-cancer compound |
| EP3672959A1 (en) | 2017-08-24 | 2020-07-01 | Asceneuron SA | Linear glycosidase inhibitors |
| WO2020039028A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Tetrahydro-benzoazepine glycosidase inhibitors |
| WO2020039027A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Pyrrolidine glycosidase inhibitors |
| US11731972B2 (en) | 2018-08-22 | 2023-08-22 | Asceneuron Sa | Spiro compounds as glycosidase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA9610738B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| TW498067B (en) * | 1996-07-19 | 2002-08-11 | Hoffmann La Roche | 4-hydroxy-piperidine derivatives |
| CA2220649C (en) | 1996-12-03 | 2007-02-13 | F. Hoffmann-La Roche Ag | 4-hydroxy-piperidine derivatives |
| CZ2004233A3 (en) * | 2001-07-24 | 2004-12-15 | Richter Gedeon Vegyészeti Gyár Rt. | Novel amide compounds of carboxylic acid |
-
2004
- 2004-07-29 HU HU0401522A patent/HUP0401522A2/en unknown
-
2005
- 2005-07-21 ES ES05763197T patent/ES2302214T3/en active Active
- 2005-07-21 CA CA002574148A patent/CA2574148A1/en not_active Abandoned
- 2005-07-21 JP JP2007523160A patent/JP4814880B2/en not_active Expired - Fee Related
- 2005-07-21 PL PL05763197T patent/PL1773810T3/en unknown
- 2005-07-21 AT AT05763197T patent/ATE387440T1/en active
- 2005-07-21 GE GEAP20059892A patent/GEP20084492B/en unknown
- 2005-07-21 SI SI200530213T patent/SI1773810T1/en unknown
- 2005-07-21 WO PCT/HU2005/000077 patent/WO2006010964A1/en active Application Filing
- 2005-07-21 BR BRPI0513902-3A patent/BRPI0513902A/en not_active IP Right Cessation
- 2005-07-21 NZ NZ552137A patent/NZ552137A/en not_active IP Right Cessation
- 2005-07-21 MX MX2007001055A patent/MX2007001055A/en active IP Right Grant
- 2005-07-21 UA UAA200702171A patent/UA87862C2/en unknown
- 2005-07-21 DE DE602005005064T patent/DE602005005064T2/en active Active
- 2005-07-21 CN CNA2005800243746A patent/CN1989128A/en active Pending
- 2005-07-21 PT PT05763197T patent/PT1773810E/en unknown
- 2005-07-21 US US11/658,789 patent/US8008326B2/en not_active Expired - Fee Related
- 2005-07-21 AP AP2006003839A patent/AP2074A/en active
- 2005-07-21 EP EP05763197A patent/EP1773810B1/en active Active
- 2005-07-21 RS RSP-2008/0123A patent/RS50573B/en unknown
- 2005-07-21 DK DK05763197T patent/DK1773810T3/en active
- 2005-07-21 KR KR1020077000262A patent/KR20070058428A/en not_active Application Discontinuation
- 2005-07-21 EA EA200700367A patent/EA011241B1/en not_active IP Right Cessation
- 2005-07-21 AU AU2005266159A patent/AU2005266159B2/en not_active Ceased
-
2006
- 2006-11-22 IL IL179484A patent/IL179484A0/en unknown
-
2007
- 2007-01-11 ZA ZA200700320A patent/ZA200700320B/en unknown
- 2007-01-17 TN TNP2007000018A patent/TNSN07018A1/en unknown
- 2007-02-22 MA MA29703A patent/MA28816B1/en unknown
- 2007-02-27 NO NO20071108A patent/NO20071108L/en not_active Application Discontinuation
- 2007-10-17 HK HK07111209A patent/HK1105966A1/en not_active IP Right Cessation
-
2008
- 2008-03-20 HR HR20080127T patent/HRP20080127T3/en unknown
- 2008-03-27 CY CY20081100349T patent/CY1107368T1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA87862C2 (en) | 4-benzylidene-piperidin derivatives | |
| MX2010001575A (en) | 1,2-diamido-ethylene derivatives as orexin antagonists. | |
| TW200833328A (en) | 2-aza-bicyclo[3.1.0]hexane derivatives | |
| MX2009009690A (en) | Thiazolidine derivatives as orexin receptor antagonists. | |
| PL2164847T3 (en) | 3-aza-bicyclo[3.3.0]octane compounds | |
| MX2009005461A (en) | N-oxides of 4,5-epoxy-morphinanium analogs. | |
| TW200605882A (en) | Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof | |
| TW200607798A (en) | Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof | |
| WO2008031556A3 (en) | 2 amino-pyrimidine derivatives as h4 receptor antagonists, processes for preparing them and their use in pharmaceutical compositions | |
| EA200700365A1 (en) | INDOL-2-CARBOXAMIDINE DERIVATIVES AS ANTAGONISTS OF NMDA RECEPTOR | |
| ATE493386T1 (en) | TRANS-3-AZA-BICYCLO-Ä3.1.0Ü-HEXANE DERIVATIVES | |
| MX2009005462A (en) | 7,8-saturated-4,5-epoxy-morphinanium analogs. | |
| MX2010008993A (en) | 2-aza-bicyclo[2.2.1]heptane derivatives. | |
| WO2008038251A3 (en) | 3-aza-bicyclo[3.1.0]hexane derivatives | |
| MX2010004576A (en) | Novel pyrimidine derivatives. | |
| DE602005012634D1 (en) | Arylsulfonylnaphthalinderivate als 5ht2a-antagonisten | |
| TW200740814A (en) | Compounds | |
| TN2009000040A1 (en) | 5,6-bisaryl-2-pyridine-carboxamide derivatives, preparation and application thereof in therapeutics as urotensin ii receptor antagonists | |
| HK1089157A1 (en) | 8-aza-bicyclo(3.2.1)octane derivatives an their use as preparing monoamine neurotransmitter re-uptake inhibitors | |
| TW200745024A (en) | Carboxamide derivatives as muscarinic receptor antagonists | |
| MX2007006042A (en) | Bengamides with a substituted caprolactame cycle, method for the preparation thereof, compositions containing them and use thereof. | |
| HK1104823A1 (en) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i | |
| MX2007003398A (en) | Sulfonamides and uses thereof. | |
| MXPA05013149A (en) | Imidazole derivatives as glutmate receptor antagonists. | |
| MXPA05013758A (en) | Pharmaceutical compositions including an antihistamine and a stimulant and use thereof. |