HUP0400261A3 - Stereoselective reduction of substituted acetophenone - Google Patents
Stereoselective reduction of substituted acetophenoneInfo
- Publication number
- HUP0400261A3 HUP0400261A3 HU0400261A HUP0400261A HUP0400261A3 HU P0400261 A3 HUP0400261 A3 HU P0400261A3 HU 0400261 A HU0400261 A HU 0400261A HU P0400261 A HUP0400261 A HU P0400261A HU P0400261 A3 HUP0400261 A3 HU P0400261A3
- Authority
- HU
- Hungary
- Prior art keywords
- stereoselective reduction
- substituted acetophenone
- acetophenone
- substituted
- stereoselective
- Prior art date
Links
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Natural products CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 title 1
- 150000008062 acetophenones Chemical class 0.000 title 1
- 238000011916 stereoselective reduction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/938—Pichia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27802501P | 2001-03-22 | 2001-03-22 | |
| PCT/US2002/006783 WO2002077258A1 (en) | 2001-03-22 | 2002-03-06 | Stereoselective reduction of substituted acetophenone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0400261A2 HUP0400261A2 (hu) | 2004-09-28 |
| HUP0400261A3 true HUP0400261A3 (en) | 2005-11-28 |
Family
ID=23063377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400261A HUP0400261A3 (en) | 2001-03-22 | 2002-03-06 | Stereoselective reduction of substituted acetophenone |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6800477B2 (hu) |
| EP (1) | EP1370677A1 (hu) |
| JP (1) | JP2004532017A (hu) |
| KR (1) | KR20030085012A (hu) |
| CN (1) | CN1498273A (hu) |
| BR (1) | BR0208265A (hu) |
| CA (1) | CA2441267A1 (hu) |
| CZ (1) | CZ20032496A3 (hu) |
| HU (1) | HUP0400261A3 (hu) |
| IL (1) | IL157386A0 (hu) |
| MX (1) | MXPA03008437A (hu) |
| PL (1) | PL364577A1 (hu) |
| WO (1) | WO2002077258A1 (hu) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003032994A2 (de) * | 2001-10-17 | 2003-04-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 5-substituierte 4-amino-2-phenylamino-pyrimidinderivate und ihre verwendung als beta-amyloid modulatoren |
| BRPI0514422A (pt) * | 2004-08-26 | 2008-06-10 | Pfizer | biotransformação enantioseletiva para o preparo de intermediários do inibidor de proteìna tirosina quinase |
| WO2007084625A2 (en) * | 2006-01-19 | 2007-07-26 | Mount Sinai School Of Medicine | Novel compounds and methods for inhibiting p53 activity |
| EP2066788B1 (en) | 2006-10-02 | 2014-07-23 | Codexis, Inc. | Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor |
| KR101502634B1 (ko) | 2007-02-08 | 2015-03-16 | 코덱시스, 인코포레이티드 | 케토 환원 효소 및 이의 용도 |
| US7977078B2 (en) | 2007-08-24 | 2011-07-12 | Codexis, Inc. | Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane |
| WO2009036404A2 (en) | 2007-09-13 | 2009-03-19 | Codexis, Inc. | Ketoreductase polypeptides for the reduction of acetophenones |
| KR20100061571A (ko) * | 2007-09-28 | 2010-06-07 | 코덱시스, 인코포레이티드 | 케토리덕타제 폴리펩티드 및 이의 용도 |
| SI2205727T1 (sl) | 2007-10-01 | 2015-09-30 | Codexis, Inc. | Polipeptidi ketoreduktaze za izdelavo azetidinona |
| WO2010025287A2 (en) | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| HUE026181T2 (hu) | 2008-08-27 | 2016-05-30 | Codexis Inc | Ketoreduktáz polipeptid 3-aril-3-hidroxipropánamin elõállítására 3-aril-3-ketopropánaminból |
| WO2010027710A2 (en) | 2008-08-27 | 2010-03-11 | Codexis, Inc. | Ketoreductase polypeptides and uses thereof |
| CN102186972B (zh) | 2008-08-29 | 2014-08-20 | 科德克希思公司 | 用于立体选择性生产(4s)-3-[(5s)-5-(4-氟苯基)-5-羟基戊酰基]-4-苯基-1，3-噁唑烷-2-酮的酮还原酶多肽 |
| DK3409765T3 (da) | 2009-06-22 | 2021-09-27 | Codexis Inc | Ketoreduktase-medieret stereoselektiv rute til alpha-chloralkoholer |
| JP5683580B2 (ja) * | 2009-06-22 | 2015-03-11 | エスケー バイオファーマシューティカル カンパニー リミテッド | カルバミン酸（ｒ）−１−アリール−２−テトラゾリル−エチルエステルの製造方法 |
| SG178456A1 (en) | 2009-08-19 | 2012-04-27 | Codexis Inc | Ketoreductase polypeptides for the preparation of phenylephrine |
| US8404461B2 (en) | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
| WO2011100265A2 (en) | 2010-02-10 | 2011-08-18 | Codexis, Inc. | Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system |
| EP2566497B1 (en) | 2010-05-04 | 2015-07-29 | Codexis, Inc. | Biocatalysts for ezetimibe synthesis |
| US20130289276A1 (en) * | 2010-10-08 | 2013-10-31 | Cadila Healthcare Limited | Process for preparing an intermediate of sitagliptin via enzymatic conversion |
| WO2013074650A1 (en) | 2011-11-18 | 2013-05-23 | Codexis, Inc. | Biocatalysts for the preparation of hydroxy substituted carbamates |
| DE102012017026A1 (de) | 2012-08-28 | 2014-03-06 | Forschungszentrum Jülich GmbH | Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen |
| EP3256577B1 (en) | 2015-02-10 | 2020-08-26 | Codexis, Inc. | Ketoreductase polypeptides for the synthesis of chiral compounds |
| CA3061133A1 (en) | 2017-04-27 | 2018-11-01 | Codexis, Inc. | Ketoreductase polypeptides and polynucleotides |
| CN107686447A (zh) * | 2017-08-25 | 2018-02-13 | 许昌恒生制药有限公司 | 一种替格瑞洛中间体的制备方法 |
| EP3587393B1 (en) | 2018-06-21 | 2024-01-17 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Enzymatic process for the preparation of droxidopa |
| KR20230165238A (ko) | 2021-04-02 | 2023-12-05 | 제넨테크, 인크. | 비시클릭 케톤 화합물 제조 공정 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0538693A3 (en) * | 1991-10-23 | 1994-08-17 | Squibb & Sons Inc | Stereoselective preparation of halophenyl alcohols |
| DK0630402T3 (da) * | 1992-03-13 | 1997-12-22 | Forschungszentrum Juelich Gmbh | Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner |
| CA2103932A1 (en) | 1992-11-05 | 1994-05-06 | Ramesh N. Patel | Stereoselective reduction of ketones |
| EP0918090A3 (en) * | 1997-11-04 | 2002-08-28 | Eli Lilly And Company | Ketoreductase gene and protein from yeast |
-
2002
- 2002-03-06 PL PL02364577A patent/PL364577A1/xx not_active Application Discontinuation
- 2002-03-06 KR KR10-2003-7012198A patent/KR20030085012A/ko not_active Application Discontinuation
- 2002-03-06 EP EP02728418A patent/EP1370677A1/en not_active Withdrawn
- 2002-03-06 CN CNA028068858A patent/CN1498273A/zh active Pending
- 2002-03-06 CA CA002441267A patent/CA2441267A1/en not_active Abandoned
- 2002-03-06 BR BR0208265-9A patent/BR0208265A/pt not_active IP Right Cessation
- 2002-03-06 MX MXPA03008437A patent/MXPA03008437A/es unknown
- 2002-03-06 IL IL15738602A patent/IL157386A0/xx unknown
- 2002-03-06 CZ CZ20032496A patent/CZ20032496A3/cs unknown
- 2002-03-06 HU HU0400261A patent/HUP0400261A3/hu unknown
- 2002-03-06 US US10/092,263 patent/US6800477B2/en not_active Expired - Lifetime
- 2002-03-06 JP JP2002576699A patent/JP2004532017A/ja active Pending
- 2002-03-06 WO PCT/US2002/006783 patent/WO2002077258A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL157386A0 (en) | 2004-02-19 |
| CN1498273A (zh) | 2004-05-19 |
| PL364577A1 (en) | 2004-12-13 |
| JP2004532017A (ja) | 2004-10-21 |
| EP1370677A1 (en) | 2003-12-17 |
| KR20030085012A (ko) | 2003-11-01 |
| HUP0400261A2 (hu) | 2004-09-28 |
| BR0208265A (pt) | 2004-03-02 |
| US6800477B2 (en) | 2004-10-05 |
| CA2441267A1 (en) | 2002-10-03 |
| WO2002077258A1 (en) | 2002-10-03 |
| CZ20032496A3 (cs) | 2003-12-17 |
| MXPA03008437A (es) | 2004-01-29 |
| US20030068811A1 (en) | 2003-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |