HUP0302539A3 - Enzymatic deprotection of amines and hydroxides - Google Patents

Enzymatic deprotection of amines and hydroxides

Info

Publication number
HUP0302539A3
HUP0302539A3 HU0302539A HUP0302539A HUP0302539A3 HU P0302539 A3 HUP0302539 A3 HU P0302539A3 HU 0302539 A HU0302539 A HU 0302539A HU P0302539 A HUP0302539 A HU P0302539A HU P0302539 A3 HUP0302539 A3 HU P0302539A3
Authority
HU
Hungary
Prior art keywords
hydroxides
amines
enzymatic deprotection
deprotection
enzymatic
Prior art date
Application number
HU0302539A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HUP0302539A2 publication Critical patent/HUP0302539A2/hu
Publication of HUP0302539A3 publication Critical patent/HUP0302539A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HU0302539A 2001-01-04 2001-12-18 Enzymatic deprotection of amines and hydroxides HUP0302539A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25971501P 2001-01-04 2001-01-04
PCT/US2001/049115 WO2002053724A2 (en) 2001-01-04 2001-12-18 Enzymatic deprotection of amines and hydroxides

Publications (2)

Publication Number Publication Date
HUP0302539A2 HUP0302539A2 (hu) 2003-11-28
HUP0302539A3 true HUP0302539A3 (en) 2010-01-28

Family

ID=22986070

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302539A HUP0302539A3 (en) 2001-01-04 2001-12-18 Enzymatic deprotection of amines and hydroxides

Country Status (14)

Country Link
US (1) US6828119B2 (hu)
EP (1) EP1348025A2 (hu)
JP (1) JP4242647B2 (hu)
KR (1) KR20030066799A (hu)
CN (2) CN100359019C (hu)
AU (1) AU2002232651B9 (hu)
BR (1) BR0116486A (hu)
CA (1) CA2433628A1 (hu)
CZ (1) CZ20031867A3 (hu)
HU (1) HUP0302539A3 (hu)
IL (1) IL156356A0 (hu)
MX (1) MXPA03005987A (hu)
PL (1) PL364642A1 (hu)
WO (1) WO2002053724A2 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119188B2 (en) 2001-01-04 2006-10-10 Bristol-Myers Squibb Company N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor
US7741082B2 (en) 2004-04-14 2010-06-22 Bristol-Myers Squibb Company Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
KR100887682B1 (ko) * 2007-05-29 2009-03-10 가톨릭대학교 산학협력단 한국산 미역귀 유래의 푸코이단 분해능을 보유한 신규한스핑고모나스속 균주
CN106434797A (zh) * 2016-08-25 2017-02-22 艾美科健（中国）生物医药有限公司 一种酶法合成泰拉霉素的工艺

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182654A (en) * 1974-09-18 1980-01-08 Pierce Chemical Company Production of polypeptides using polynucleotides
NZ241625A (en) * 1991-02-22 1996-03-26 Univ Emory 1,3-oxathiolane derivatives, anti-viral compositions containing such and method of resolving racemic mixture of enantiomers
US5552397A (en) * 1992-05-18 1996-09-03 E. R. Squibb & Sons, Inc. Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
WO1995018781A1 (en) * 1994-01-06 1995-07-13 Metabolix, Inc. Methods for synthesizing oligomers containing hydroxy acid units
US5445959A (en) * 1994-07-15 1995-08-29 Eli Lilly And Company Enzyme from microbial source: phthalyl amidase
US5571796A (en) * 1995-06-06 1996-11-05 Alberta Research Council Administration of valienamine-related disaccharide compounds in reducing inflammation in a sensitized mammal arising from exposure to an antigen
US5981267A (en) * 1996-01-24 1999-11-09 The Scripps Research Institute Enantioselection of amines using homocarbonates with hydrolase
PL334293A1 (en) * 1996-12-27 2000-02-14 Smithkline Beecham Plc Enzymatic separation of benzodiazepinacetic esters by means of lipase
CA2360305A1 (en) 1999-02-09 2000-08-17 Bristol-Myers Squibb Company Lactam inhibitors of fxa and method

Also Published As

Publication number Publication date
CN100359019C (zh) 2008-01-02
JP4242647B2 (ja) 2009-03-25
AU2002232651B2 (en) 2007-04-19
CN1237171C (zh) 2006-01-18
WO2002053724A3 (en) 2003-01-16
IL156356A0 (en) 2004-01-04
MXPA03005987A (es) 2003-09-10
KR20030066799A (ko) 2003-08-09
CA2433628A1 (en) 2002-07-11
WO2002053724A2 (en) 2002-07-11
US20020123110A1 (en) 2002-09-05
EP1348025A2 (en) 2003-10-01
AU2002232651A1 (en) 2002-07-16
BR0116486A (pt) 2004-08-17
US6828119B2 (en) 2004-12-07
CN1775951A (zh) 2006-05-24
HUP0302539A2 (hu) 2003-11-28
CN1484695A (zh) 2004-03-24
AU2002232651B9 (en) 2007-05-31
JP2004520030A (ja) 2004-07-08
PL364642A1 (en) 2004-12-13
CZ20031867A3 (en) 2004-03-17

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees