HUP0200241A2 - Hisztidin-fehérjefoszfatáz - Google Patents
Hisztidin-fehérjefoszfatázInfo
- Publication number
- HUP0200241A2 HUP0200241A2 HU0200241A HUP0200241A HUP0200241A2 HU P0200241 A2 HUP0200241 A2 HU P0200241A2 HU 0200241 A HU0200241 A HU 0200241A HU P0200241 A HUP0200241 A HU P0200241A HU P0200241 A2 HUP0200241 A2 HU P0200241A2
- Authority
- HU
- Hungary
- Prior art keywords
- phosphatase
- enzyme
- histidine phosphatase
- histidine
- histidine protein
- Prior art date
Links
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 title abstract 3
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 title abstract 2
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 230000001575 pathological effect Effects 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 abstract 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 230000009134 cell regulation Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
A találmány tárgyát képezi hisztidin-foszfatáz biológiai aktivitású,új, emlőseredetű enzim és homológ variánsai. A találmány tárgyátképezik továbbá a fehérjéket kódoló DNS-ek, a fehérjéket tartalmazógyó- gyászati készítmények és a velük szemben termelt ellenanyagok. Atalálmány szerinti hisztidin-foszfatáz sejtszabályozás éssejtnövekedés patológiás állapotainak diagnózisára alkalmazható,valamint az enzim helytelen működésével kapcsolatos patológiásrendellenességekkel kapcsolatosan adagolható gyógyászatihatóanyagként. Ó
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19909388 | 1999-03-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0200241A2 true HUP0200241A2 (hu) | 2002-05-29 |
Family
ID=7899608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0200241A HUP0200241A2 (hu) | 1999-03-04 | 2000-03-02 | Hisztidin-fehérjefoszfatáz |
Country Status (22)
Country | Link |
---|---|
US (1) | US6812015B1 (hu) |
EP (1) | EP1159430B1 (hu) |
JP (1) | JP2002537814A (hu) |
KR (1) | KR20020002400A (hu) |
CN (1) | CN1201009C (hu) |
AR (1) | AR022836A1 (hu) |
AT (1) | ATE393827T1 (hu) |
AU (1) | AU762809B2 (hu) |
BR (1) | BR0008607A (hu) |
CA (1) | CA2364495A1 (hu) |
CZ (1) | CZ20013172A3 (hu) |
DE (1) | DE60038731T2 (hu) |
ES (1) | ES2303813T3 (hu) |
HK (1) | HK1042729A1 (hu) |
HU (1) | HUP0200241A2 (hu) |
MX (1) | MXPA01008941A (hu) |
NO (1) | NO20014261D0 (hu) |
PL (1) | PL350323A1 (hu) |
RU (1) | RU2281973C2 (hu) |
SK (1) | SK12242001A3 (hu) |
WO (1) | WO2000052175A1 (hu) |
ZA (1) | ZA200108129B (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1363941A2 (en) * | 2001-02-16 | 2003-11-26 | MERCK PATENT GmbH | Histidine phosphatase interacting protein of 120 kd |
MXPA03007990A (es) * | 2001-03-08 | 2003-12-04 | Merck Patent Gmbh | Uso de la proteina histidina fosfatasa. |
AU2003280359A1 (en) * | 2002-11-09 | 2004-06-03 | Merck Patent Gmbh | Phosphoamidase assay |
US9052304B2 (en) | 2009-03-13 | 2015-06-09 | Terrasep, Llc | Methods and apparatus for centrifugal liquid chromatography |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19811194A1 (de) * | 1998-03-10 | 1999-09-16 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Prostatagewebe |
-
2000
- 2000-03-02 DE DE60038731T patent/DE60038731T2/de not_active Expired - Fee Related
- 2000-03-02 HU HU0200241A patent/HUP0200241A2/hu unknown
- 2000-03-02 JP JP2000602786A patent/JP2002537814A/ja active Pending
- 2000-03-02 CN CNB008046476A patent/CN1201009C/zh not_active Expired - Fee Related
- 2000-03-02 AU AU38080/00A patent/AU762809B2/en not_active Ceased
- 2000-03-02 AT AT00916889T patent/ATE393827T1/de not_active IP Right Cessation
- 2000-03-02 KR KR1020017011279A patent/KR20020002400A/ko active IP Right Grant
- 2000-03-02 EP EP00916889A patent/EP1159430B1/en not_active Expired - Lifetime
- 2000-03-02 CA CA002364495A patent/CA2364495A1/en not_active Abandoned
- 2000-03-02 SK SK1224-2001A patent/SK12242001A3/sk unknown
- 2000-03-02 MX MXPA01008941A patent/MXPA01008941A/es not_active Application Discontinuation
- 2000-03-02 ES ES00916889T patent/ES2303813T3/es not_active Expired - Lifetime
- 2000-03-02 WO PCT/EP2000/001774 patent/WO2000052175A1/en active IP Right Grant
- 2000-03-02 CZ CZ20013172A patent/CZ20013172A3/cs unknown
- 2000-03-02 PL PL00350323A patent/PL350323A1/xx unknown
- 2000-03-02 BR BR0008607-0A patent/BR0008607A/pt not_active IP Right Cessation
- 2000-03-02 US US09/914,831 patent/US6812015B1/en not_active Expired - Fee Related
- 2000-03-02 RU RU2001126572/13A patent/RU2281973C2/ru not_active IP Right Cessation
- 2000-03-03 AR ARP000100970A patent/AR022836A1/es not_active Application Discontinuation
-
2001
- 2001-09-03 NO NO20014261A patent/NO20014261D0/no not_active Application Discontinuation
- 2001-10-03 ZA ZA200108129A patent/ZA200108129B/xx unknown
-
2002
- 2002-05-31 HK HK02104048.2A patent/HK1042729A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CA2364495A1 (en) | 2000-09-08 |
CZ20013172A3 (cs) | 2001-12-12 |
ATE393827T1 (de) | 2008-05-15 |
US6812015B1 (en) | 2004-11-02 |
DE60038731T2 (de) | 2009-07-02 |
NO20014261L (no) | 2001-09-03 |
RU2281973C2 (ru) | 2006-08-20 |
JP2002537814A (ja) | 2002-11-12 |
WO2000052175A1 (en) | 2000-09-08 |
MXPA01008941A (es) | 2002-06-26 |
HK1042729A1 (zh) | 2002-08-23 |
BR0008607A (pt) | 2002-01-02 |
EP1159430B1 (en) | 2008-04-30 |
AU3808000A (en) | 2000-09-21 |
AU762809B2 (en) | 2003-07-03 |
SK12242001A3 (sk) | 2002-06-04 |
KR20020002400A (ko) | 2002-01-09 |
ZA200108129B (en) | 2003-03-26 |
AR022836A1 (es) | 2002-09-04 |
CN1201009C (zh) | 2005-05-11 |
ES2303813T3 (es) | 2008-09-01 |
EP1159430A1 (en) | 2001-12-05 |
NO20014261D0 (no) | 2001-09-03 |
PL350323A1 (en) | 2002-12-02 |
DE60038731D1 (de) | 2008-06-12 |
CN1342205A (zh) | 2002-03-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KAWAKAMI et al. | Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells | |
Majka et al. | Regulation of matrix metalloproteinase expression by tumor necrosis factor in a murine model of retinal neovascularization | |
Golub et al. | Enhanced collagenase activity in diabetic rat gingiva: in vitro and in vivo evidence | |
FR14C0051I2 (fr) | Dialkylfumarates pour le traitement de maladies autoimmunes | |
Hassell | Evidence for production of an inactive collagenase by fibroblasts from phenytoin‐enlarged human gingivae | |
HUP9800028A2 (hu) | Több tumor esetében rendellenes sejtszaporodás előidézésében közrejátszó gének | |
ATE65505T1 (de) | Biologisch aktive fragmente von humanem antihaemophiliefaktor, methode zu ihrer herstellung und pharmazeutische praeparate. | |
ATE249422T1 (de) | Verbindungen und zusammensetzungen zur verabreichung aktiver stoffe | |
DE59811158D1 (de) | Verwendung von erythropoietin und eisenpräparaten zur herstellung von pharmazeutischen kombinationspräparaten zur behandlung von rheumatischen erkrankungen | |
PT750672E (pt) | Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao. | |
WO1995028907A3 (en) | Megapoietin: a novel megakaryocyte growth promoting factor | |
WO2001016292A8 (en) | 37 staphylococcus aureus genes and polypeptides | |
AU8439998A (en) | Compounds | |
Russell et al. | Distribution of putrescine, spermidine, and spermine in rhesus monkey brain: Decrease in spermidine and spermine concentrations in motor cortex after electrical stimulation | |
HUP0200241A2 (hu) | Hisztidin-fehérjefoszfatáz | |
Kawakita et al. | Characterization of human megakaryocyte colony-stimulating factor in the urinary extracts from patients with aplastic anemia and idiopathic thrombocytopenic purpura | |
Puzynski et al. | Studies on biogenic amine metabolizing enzymes (DBH, COMT, MAO) and pathogenesis of affective illness: II. Erythrocyte catechol‐O‐methyltransferase activity in endogenous depression | |
EP0826367A3 (fr) | Utilisation d'un extrait de Bertholletia dans le domaine cosmétique ou pharmaceutique, et pour la préparation de milieux de cultures de cellules | |
WO1998039429A3 (en) | Compositions for treatment of disorders involving programmed cell death | |
FR2603040B1 (fr) | Proteine, sequence d'adn, poxvirus, cellules et leur procede de culture, ainsi que les compositions pharmaceutiques les contenant, utiles dans la prevention de la schistosomose | |
Conn et al. | Peptidases and neuropeptide processing | |
Söder | Proteolytic Activity of Dental Plaque Material: VI. Fractionation of Dental Plaque Extract by gel Filtration on Sephadex and by Zone Electrophoresis | |
DE50004024D1 (de) | Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation | |
BR9709379A (pt) | Uso de uridina, e, composição para o tratamento de distúrbios do sistema nervoso devido à degeneração seletiva de células neuroniais ou gliais em mamìferos. | |
Kikuchi et al. | Chronic renal failure patient with membranous nephropathy on CAPD presenting with macro creatine kinase type 1 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |