HUP0105035A2 - Mammalian serine racemase - Google Patents
Mammalian serine racemaseInfo
- Publication number
- HUP0105035A2 HUP0105035A2 HU0105035A HUP0105035A HUP0105035A2 HU P0105035 A2 HUP0105035 A2 HU P0105035A2 HU 0105035 A HU0105035 A HU 0105035A HU P0105035 A HUP0105035 A HU P0105035A HU P0105035 A2 HUP0105035 A2 HU P0105035A2
- Authority
- HU
- Hungary
- Prior art keywords
- enzymes
- present
- expression vectors
- serine racemase
- mammalian serine
- Prior art date
Links
- 108010006152 Serine racemase Proteins 0.000 title 1
- 102100035717 Serine racemase Human genes 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 5
- 108090000790 Enzymes Proteins 0.000 abstract 5
- 239000013604 expression vector Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A tal lm ny t rgy t emlőseredetű, aminosav racem z enzimek és azenzimeket tartalmazó készítmények képezik. A tal lm ny t rgy t képeziktov bb a tal lm ny szerinti enzimeket kódoló polinukleotidok, apolinukleotidokat tartalmazó expressziós vektorok, az expressziósvektorokat hordozó gazdasejtek, valamint elj r sok a tal lm nyszerinti enzimek elő llít s ra. A tal lm ny t rgy t képezik a tal lmny szerinti enzimek aktivit s nak modul l s ra képes ter pi shatóanyagok izol l s ra szolg ló elj r sok is. A tal lm ny szerintimegold s alkalmas új, idegrendszeri megbetegedések kezelésére hasznlható hatóanyagok azonosít s ra. ÓThis product consists of preparations containing amino acid racemic enzymes and non-enzymes of mammalian origin. The present material mainly consists of polynucleotides encoding the present enzymes, expression vectors containing apolynucleotides, host cells carrying the expression vectors, and methods for the production of the present enzymes. The material of the invention also includes procedures for the isolation of infectious substances capable of modulating the activity of the enzymes according to the invention. According to the evidence, it is suitable and suitable for the identification of new active substances that can be used for the treatment of nervous system diseases. HE
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11633399P | 1999-01-19 | 1999-01-19 | |
| US14483999P | 1999-07-21 | 1999-07-21 | |
| US14595399P | 1999-07-28 | 1999-07-28 | |
| PCT/US2000/000938 WO2000043526A1 (en) | 1999-01-19 | 2000-01-18 | Mammalian serine racemase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0105035A2 true HUP0105035A2 (en) | 2002-04-29 |
Family
ID=27381812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0105035A HUP0105035A2 (en) | 1999-01-19 | 2000-01-18 | Mammalian serine racemase |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1147203A1 (en) |
| JP (1) | JP2002534984A (en) |
| KR (1) | KR20010103740A (en) |
| AU (1) | AU2413500A (en) |
| BR (1) | BR0007592A (en) |
| CA (1) | CA2360724A1 (en) |
| HU (1) | HUP0105035A2 (en) |
| IL (1) | IL144102A0 (en) |
| MX (1) | MXPA01007310A (en) |
| NO (1) | NO20013557L (en) |
| PL (1) | PL364984A1 (en) |
| TR (1) | TR200102081T2 (en) |
| WO (1) | WO2000043526A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001241583A1 (en) | 2000-02-17 | 2001-08-27 | Millennium Pharmaceuticals, Inc. | A human pyridoxal-phosphate dependent enzyme family member and uses therefor |
| EP1272646A2 (en) * | 2000-03-31 | 2003-01-08 | Bayer Aktiengesellschaft | Regulation of human serine racemase enzyme |
| US20030212262A1 (en) * | 2000-04-04 | 2003-11-13 | Connolly Thomas M | Human serine racemase |
| JP4857071B2 (en) * | 2006-10-12 | 2012-01-18 | 潤平 笹部 | Method for detecting amyotrophic side sclerosis (ALS) |
| CN109251923B (en) * | 2018-10-22 | 2021-06-15 | 天津博瑞威生物医药科技有限公司 | Serine racemase mutants |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2048266B (en) * | 1979-05-09 | 1983-11-30 | Mitsui Toatsu Chemicals | Enzymatic preparation of l-tryptophan |
-
2000
- 2000-01-18 JP JP2000594934A patent/JP2002534984A/en active Pending
- 2000-01-18 EP EP00902414A patent/EP1147203A1/en not_active Withdrawn
- 2000-01-18 BR BR0007592-2A patent/BR0007592A/en not_active Application Discontinuation
- 2000-01-18 PL PL00364984A patent/PL364984A1/en not_active Application Discontinuation
- 2000-01-18 WO PCT/US2000/000938 patent/WO2000043526A1/en not_active Application Discontinuation
- 2000-01-18 HU HU0105035A patent/HUP0105035A2/en unknown
- 2000-01-18 CA CA002360724A patent/CA2360724A1/en not_active Abandoned
- 2000-01-18 TR TR2001/02081T patent/TR200102081T2/en unknown
- 2000-01-18 KR KR1020017009013A patent/KR20010103740A/en not_active Application Discontinuation
- 2000-01-18 AU AU24135/00A patent/AU2413500A/en not_active Abandoned
- 2000-01-18 MX MXPA01007310A patent/MXPA01007310A/en not_active IP Right Cessation
- 2000-01-18 IL IL14410200A patent/IL144102A0/en unknown
-
2001
- 2001-07-18 NO NO20013557A patent/NO20013557L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2360724A1 (en) | 2000-07-27 |
| NO20013557D0 (en) | 2001-07-18 |
| TR200102081T2 (en) | 2001-11-21 |
| KR20010103740A (en) | 2001-11-23 |
| JP2002534984A (en) | 2002-10-22 |
| EP1147203A1 (en) | 2001-10-24 |
| PL364984A1 (en) | 2004-12-27 |
| NO20013557L (en) | 2001-09-19 |
| WO2000043526A1 (en) | 2000-07-27 |
| AU2413500A (en) | 2000-08-07 |
| BR0007592A (en) | 2001-11-06 |
| MXPA01007310A (en) | 2002-04-24 |
| IL144102A0 (en) | 2002-05-23 |
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