HUP0101081A2 - Medium and method for viral propagation and growth - Google Patents

Medium and method for viral propagation and growth

Info

Publication number
HUP0101081A2
HUP0101081A2 HU0101081A HUP0101081A HUP0101081A2 HU P0101081 A2 HUP0101081 A2 HU P0101081A2 HU 0101081 A HU0101081 A HU 0101081A HU P0101081 A HUP0101081 A HU P0101081A HU P0101081 A2 HUP0101081 A2 HU P0101081A2
Authority
HU
Hungary
Prior art keywords
medium
growth
viral propagation
propagation
proteins
Prior art date
Application number
HU0101081A
Other languages
Hungarian (hu)
Inventor
Pierre Heimindinger
Original Assignee
Aventis Pasteur
Merial S.A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur, Merial S.A.S. filed Critical Aventis Pasteur
Publication of HUP0101081A2 publication Critical patent/HUP0101081A2/en
Publication of HUP0101081A3 publication Critical patent/HUP0101081A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • A61K39/13Poliovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/205Rhabdoviridae, e.g. rabies virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0043Medium free of human- or animal-derived components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/76Undefined extracts from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32651Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A találmány tárgyát tápközeg és eljárás képezi tenyésztett sejtekenvégrehajtott vírustenyésztésre és vírusszaporításra. A találmányszerinti tápközeg humán vagy állati proteinektől - még rekombinánseredetű proteinektől is - mentes, és növényi extraktumokat vagynövényi extraktum hidrolizátumokat tartalmaz. A találmány szerintitápközeg és eljárás alkalmas vakcinák előállítására. ÓThe subject of the invention is a culture medium and a method for virus cultivation and propagation of viruses performed on cultured cells. The medium according to the invention is free of human or animal proteins - even proteins of recombinant origin - and contains plant extracts or plant extract hydrolysates. The nutrient medium and method according to the invention are suitable for the production of vaccines. HE

HU0101081A 1998-03-13 1999-03-15 Medium and method for viral propagation and growth HUP0101081A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9803333A FR2775983B1 (en) 1998-03-13 1998-03-13 VIRAL PROPAGATION AND MULTIPLICATION MEDIUM AND METHOD
PCT/FR1999/000578 WO1999047648A2 (en) 1998-03-13 1999-03-15 Medium and method for viral propagation and growth

Publications (2)

Publication Number Publication Date
HUP0101081A2 true HUP0101081A2 (en) 2001-07-30
HUP0101081A3 HUP0101081A3 (en) 2003-04-28

Family

ID=9524203

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101081A HUP0101081A3 (en) 1998-03-13 1999-03-15 Medium and method for viral propagation and growth

Country Status (16)

Country Link
EP (1) EP1062324A2 (en)
JP (1) JP2002506636A (en)
KR (1) KR20010072556A (en)
CN (1) CN1301297A (en)
AU (1) AU752577B2 (en)
BR (1) BR9908744A (en)
CA (1) CA2322619A1 (en)
EA (1) EA200000934A1 (en)
FR (1) FR2775983B1 (en)
HU (1) HUP0101081A3 (en)
IL (1) IL138250A0 (en)
NZ (1) NZ506872A (en)
PL (1) PL343557A1 (en)
SK (1) SK12882000A3 (en)
TR (1) TR200002641T2 (en)
WO (1) WO1999047648A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000083657A (en) * 1998-07-13 2000-03-28 Chemo Sero Therapeut Res Inst Japanese encephalitis virus vaccine
AT409379B (en) * 1999-06-02 2002-07-25 Baxter Ag MEDIUM FOR PROTEIN- AND SERUM-FREE CELL CULTURE
CA2441688C (en) * 2001-03-27 2014-01-21 Vertex Pharmaceuticals Incorporated Compositions and methods useful for hcv infection
DK2287288T3 (en) * 2002-07-09 2013-01-07 Baxter Int Medium free of animal protein for cell culture
GB0304799D0 (en) 2003-03-03 2003-04-09 Glaxosmithkline Biolog Sa Novel method
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
DK2522717T3 (en) 2006-01-04 2014-04-22 Baxter Int Oligopeptide-free cell culture media
JP5458536B2 (en) * 2008-09-17 2014-04-02 不二製油株式会社 Method for producing lactic acid and additive for lactic acid fermentation
CN107043739A (en) * 2017-04-24 2017-08-15 浙江美保龙生物技术有限公司 A kind of Vero cell culture solution additive and preparation method thereof, application method
CN107129963A (en) * 2017-04-24 2017-09-05 浙江美保龙生物技术有限公司 A kind of cell culture solution additives of DF 1 and preparation method thereof, application method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498537A (en) * 1994-03-09 1996-03-12 Cellco, Inc. Serum-free production of packaged viral vector
FR2732347A1 (en) * 1995-03-30 1996-10-04 Bio Media Plant extract used as cell growth factor medicament with antitumoural and anticancer activity
EP0912191B1 (en) * 1997-04-16 2003-04-09 Feva N.V. Vegetable extract, method for preparation thereof and its applications in human and veterinary medicine

Also Published As

Publication number Publication date
WO1999047648A2 (en) 1999-09-23
EA200000934A1 (en) 2001-02-26
PL343557A1 (en) 2001-08-27
CA2322619A1 (en) 1999-09-23
CN1301297A (en) 2001-06-27
HUP0101081A3 (en) 2003-04-28
JP2002506636A (en) 2002-03-05
AU752577B2 (en) 2002-09-26
WO1999047648A3 (en) 1999-11-04
IL138250A0 (en) 2001-10-31
EP1062324A2 (en) 2000-12-27
SK12882000A3 (en) 2001-05-10
NZ506872A (en) 2002-03-01
TR200002641T2 (en) 2000-11-21
KR20010072556A (en) 2001-07-31
FR2775983A1 (en) 1999-09-17
AU2735299A (en) 1999-10-11
BR9908744A (en) 2000-12-26
FR2775983B1 (en) 2000-11-10

Similar Documents

Publication Publication Date Title
EA200200604A1 (en) PRODUCTION VACCINES
DK0983342T3 (en) Culture medium with soybean extract as amino acid source and no animal complexes of animal origin
MXPA05009096A (en) Animal-free cell culture method.
HK1019233A1 (en) Animal cells and processes for the replication of influenza viruses
HK1108713A1 (en) Animal protein free media for cultivation of cells
ATE289348T1 (en) METHODS OF INCREASE VIRAL VACCINE PRODUCTION IN CELL CULTURE BY SUPPRESSING INTERFERON
WO1999057246A8 (en) Animal cell culture media comprising non-animal or plant-derived nutrients
AU4751697A (en) Animal cell culture media comprising plant-derived nutrients
CA2494379A1 (en) Method for the cultivation of primary cells and for the amplification of viruses under serum free conditions
HUP0101081A2 (en) Medium and method for viral propagation and growth
DE60218327D1 (en) INACTIVATED IMMUNOGENIC BACTERIAL ALL-CELL COMPOSITIONS
HU9202009D0 (en) Matrix with adherently bound cells and method for producing viruses and antigens thereof
DE60038045D1 (en) NON-PATHOGEN KINETOPLASTIDE PROTEIN EXPRESSION SYSTEM
JPS6485092A (en) Production of protein
CA2250714A1 (en) Animal cells and processes for the replication of influenza viruses