HUP0104803A2 - Eljárás és rendszer bőrön át felszívódó gyógyszer adagolására - Google Patents

Eljárás és rendszer bőrön át felszívódó gyógyszer adagolására

Info

Publication number
HUP0104803A2
HUP0104803A2 HU0104803A HUP0104803A HUP0104803A2 HU P0104803 A2 HUP0104803 A2 HU P0104803A2 HU 0104803 A HU0104803 A HU 0104803A HU P0104803 A HUP0104803 A HU P0104803A HU P0104803 A2 HUP0104803 A2 HU P0104803A2
Authority
HU
Hungary
Prior art keywords
skin
drug
subject
administration
medicine
Prior art date
Application number
HU0104803A
Other languages
English (en)
Inventor
David Louis Charles Solomon
Montague Cecil Solomon
Biljana Tocili
Original Assignee
Dermatech Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermatech Limited filed Critical Dermatech Limited
Publication of HUP0104803A2 publication Critical patent/HUP0104803A2/hu
Publication of HUP0104803A3 publication Critical patent/HUP0104803A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

A találmány tárgya eljárás gyógyszernek bőrön keresztüli felszívódásátbiztosító adagolórendszer (tapasz) előállítására olymódon, hogy azeljárás során a gyógyászatilag aktív anyagot a telítési szintnélkisebb koncentrációban oldják fel olyan oldószerben, amely egyidejűlegelő is segíti a gyógyszer behatolását a bőrbe, majd az így kapottoldatot összekeverik egy vizes diszperzió vagy vizes oldat formájábanjelenlévő tapadó anyaggal. A találmány tárgya továbbá az eljárássalkialakított rendszer. Ó
HU0104803A 1998-12-24 1999-11-17 Process and system for the administration of medicine through the skin HUP0104803A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9828480.5A GB9828480D0 (en) 1998-12-24 1998-12-24 Transdermal drug delivery system

Publications (2)

Publication Number Publication Date
HUP0104803A2 true HUP0104803A2 (hu) 2002-05-29
HUP0104803A3 HUP0104803A3 (en) 2006-07-28

Family

ID=10844919

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104803A HUP0104803A3 (en) 1998-12-24 1999-11-17 Process and system for the administration of medicine through the skin

Country Status (18)

Country Link
US (1) US20050287195A1 (hu)
EP (1) EP1140038B1 (hu)
JP (1) JP2002533384A (hu)
KR (1) KR100624235B1 (hu)
AT (1) ATE287262T1 (hu)
AU (1) AU756975B2 (hu)
CA (1) CA2356391C (hu)
DE (1) DE69923348T9 (hu)
ES (1) ES2235533T3 (hu)
GB (2) GB9828480D0 (hu)
HU (1) HUP0104803A3 (hu)
IL (2) IL143925A0 (hu)
NZ (1) NZ513051A (hu)
PL (1) PL194291B1 (hu)
PT (1) PT1140038E (hu)
WO (1) WO2000038659A1 (hu)
YU (1) YU45301A (hu)
ZA (1) ZA200106020B (hu)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003059542A1 (en) 2002-01-17 2003-07-24 Lts Lohmann Therapie-Systeme Ag Method for neutralizing or recycling carrier materials for film-like coatings
JP5027373B2 (ja) * 2002-08-09 2012-09-19 帝國製薬株式会社 エストラジオール含有貼付剤
AU2003254834B2 (en) * 2002-08-09 2009-02-19 Fuso Pharmaceutical Industries, Ltd. Female hormone-containing patch
AU2005244214B2 (en) * 2004-04-29 2010-02-18 Teikoku Pharma Usa, Inc. Topical methadone compositions and methods for using the same
KR101802553B1 (ko) 2010-09-23 2017-11-28 모노졸 알엑스, 엘엘씨 제약 생성물을 패키지 표면 상에 직접적으로 형성시키는 방법 및 시스템
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2014188329A2 (en) * 2013-05-20 2014-11-27 Mylan, Inc. Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US20210000754A1 (en) * 2019-07-02 2021-01-07 Clifford T. Rowley Transdermal patch providing improved permeability and composition

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
JPS62106013A (ja) * 1985-10-31 1987-05-16 Kowa Co 外用投与用組成物
JPH0794394B2 (ja) * 1986-12-24 1995-10-11 前田薬品工業株式会社 消炎鎮痛外用貼付剤
HU203285B (en) * 1988-02-01 1991-07-29 Egyt Gyogyszervegyeszeti Gyar Method for producing transdermal preparation containing vegetable extract
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
CA2066249C (en) * 1990-05-17 1997-12-16 Akira Nakagawa Estradiol percutaneous administration preparations
GB9021674D0 (en) * 1990-10-05 1990-11-21 Ethical Pharma Ltd Transdermal device
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
US5164190A (en) * 1990-12-11 1992-11-17 Theratech, Inc. Subsaturated transdermal drug delivery device exhibiting enhanced drug flux
JP2960832B2 (ja) * 1992-05-08 1999-10-12 ペルマテック テクノロジー アクチェンゲゼルシャフト エストラジオールの投与システム
GB2273044B (en) * 1992-12-02 1997-04-09 Pacific Chem Co Ltd Medicinal patches for percutaneous administration
JPH09208469A (ja) * 1996-02-02 1997-08-12 Mikasa Seiyaku Kk 経皮吸収貼付剤
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
IT1283102B1 (it) * 1996-06-06 1998-04-07 Permatec Nv Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents

Also Published As

Publication number Publication date
GB2345246B (en) 2001-07-25
EP1140038A1 (en) 2001-10-10
CA2356391C (en) 2006-10-10
ATE287262T1 (de) 2005-02-15
CA2356391A1 (en) 2000-07-06
PL349077A1 (en) 2002-07-01
PL194291B1 (pl) 2007-05-31
AU756975B2 (en) 2003-01-30
DE69923348D1 (de) 2005-02-24
ES2235533T3 (es) 2005-07-01
ZA200106020B (en) 2002-02-28
JP2002533384A (ja) 2002-10-08
YU45301A (sh) 2004-05-12
KR20010093223A (ko) 2001-10-27
DE69923348T2 (de) 2006-04-06
US20050287195A1 (en) 2005-12-29
IL143925A (en) 2006-06-11
HUP0104803A3 (en) 2006-07-28
DE69923348T9 (de) 2006-08-10
WO2000038659A1 (en) 2000-07-06
NZ513051A (en) 2002-12-20
GB2345246A (en) 2000-07-05
EP1140038B1 (en) 2005-01-19
AU1067800A (en) 2000-07-31
GB9828480D0 (en) 1999-02-17
GB9927038D0 (en) 2000-01-12
IL143925A0 (en) 2002-04-21
KR100624235B1 (ko) 2006-09-13
PT1140038E (pt) 2005-04-29

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees