HUP0104519A2 - Eljárások antigén-szekvenciák azonosítására - Google Patents

Eljárások antigén-szekvenciák azonosítására

Info

Publication number
HUP0104519A2
HUP0104519A2 HU0104519A HUP0104519A HUP0104519A2 HU P0104519 A2 HUP0104519 A2 HU P0104519A2 HU 0104519 A HU0104519 A HU 0104519A HU P0104519 A HUP0104519 A HU P0104519A HU P0104519 A2 HUP0104519 A2 HU P0104519A2
Authority
HU
Hungary
Prior art keywords
gene sequences
subject
nucleotide sequence
methods
expression
Prior art date
Application number
HU0104519A
Other languages
English (en)
Inventor
Timothy James Duran
Robert John Moore
Original Assignee
Commonwealth Scientific And Industrial Research Organisation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commonwealth Scientific And Industrial Research Organisation filed Critical Commonwealth Scientific And Industrial Research Organisation
Publication of HUP0104519A2 publication Critical patent/HUP0104519A2/hu
Publication of HUP0104519A3 publication Critical patent/HUP0104519A3/hu

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1086Preparation or screening of expression libraries, e.g. reporter assays
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/41Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/42Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány tárgyát potenciális vakcinaantigének génszekvenciáinakazonosítására szolgáló eljárások képezik. A találmány tárgyát képeziktehát a génszekvenciák és a génszekvenciák által kódolt polipeptidek,illetve az ilyen szekvenciák alkalmazása védekező immunválaszindukálására állatokban. Konkrétan, a találmány tárgya Mycoplasma,<>előnyösen Mycoplasma hyopneumoniae potenciális antigéngénszekvenciáinak azonosítása. A találmány egy szempontja szerint a találmány tárgyát olyaneljárás képezi, amellyel expressziós vektorban lévőnukleotidszekvenciáról transzlálódott expressziós proteineket mutatunkki, és amely eljárás a nukleotidszekvenciából transzlálódott proteinés valamilyen marker együttes expressziójának alkalmazásáttartalmazza. A találmány egy másik szempontja szerint a találmánytárgya eljárás valamely betegség terápiás szempontból figyelembevehető, antigén tulajdonságú proteinjét kódoló terápiás antigéngénszekvenciájának nukleotidszekvencia-mintából történő azonosítására.A marker előnyösen poli-His-toldalék. Ó
HU0104519A 1998-11-20 1999-11-19 Methods of indentifying antigen gene sequences HUP0104519A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPP7273A AUPP727398A0 (en) 1998-11-20 1998-11-20 Methods of identifying antigen gene sequences
PCT/AU1999/001035 WO2000031115A1 (en) 1998-11-20 1999-11-19 Methods of identifying antigen gene sequences

Publications (2)

Publication Number Publication Date
HUP0104519A2 true HUP0104519A2 (hu) 2002-03-28
HUP0104519A3 HUP0104519A3 (en) 2004-10-28

Family

ID=3811482

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104519A HUP0104519A3 (en) 1998-11-20 1999-11-19 Methods of indentifying antigen gene sequences

Country Status (13)

Country Link
US (1) US6759516B2 (hu)
EP (1) EP1140978A4 (hu)
JP (1) JP2002535604A (hu)
KR (1) KR100810699B1 (hu)
CN (1) CN1331699A (hu)
AU (1) AUPP727398A0 (hu)
BR (1) BR9915066A (hu)
CA (1) CA2351736A1 (hu)
HU (1) HUP0104519A3 (hu)
MX (1) MXPA01005011A (hu)
NZ (1) NZ511623A (hu)
WO (1) WO2000031115A1 (hu)
ZA (1) ZA200103677B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2436986A1 (en) * 2001-02-07 2002-08-15 Invitrogen Corporation Ter sites and ter binding proteins
SI1546357T1 (sl) 2002-06-28 2013-10-30 Iowa State University Research Foundation, Inc. Imunogeni polipeptidi mycoplasma hyopneumoniae
WO2006050571A1 (en) * 2004-11-11 2006-05-18 Queensland University Of Technology Chlamydia antigens and uses thereof
CN101851661B (zh) * 2010-05-10 2015-09-09 其昌達生物高科技(上海)有限公司 非诊断目的的在a-peg-b列阵下加快检测支原体时间的方法
WO2015123728A1 (en) * 2014-02-18 2015-08-27 University Of Technology, Sydney Mycoplasma surface proteins and uses thereof
BR102014014727B1 (pt) * 2014-06-16 2018-04-03 Ouro Fino Saúde Animal Ltda COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, GENE SINTÉTICO CODIFICANTE DO COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, COMPOSIÇÃO ANTIGÊNICA, PROCESSO DE OBTENÇÃO DE UM COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae
WO2018078167A1 (en) * 2016-10-31 2018-05-03 Universität Zürich Protein screening and detection method
CN112979769B (zh) * 2021-03-08 2023-01-31 珠海丽禾医疗诊断产品有限公司 一种氨基酸序列、蛋白质及其制备方法和应用
CN113185588A (zh) * 2021-04-28 2021-07-30 华中农业大学 一种牛支原体MbovP701蛋白及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68925769T2 (de) * 1988-06-29 1996-08-08 Ml Technology Ventures Rekombinantes hyopneumoniae Antigen und dessen Verwendung
WO1993003157A1 (en) * 1991-07-29 1993-02-18 Dana Farber Cancer Institute Plasmids for the rapid preparation of modified proteins
US5703057A (en) * 1995-04-07 1997-12-30 Board Of Regents The University Of Texas System Expression library immunization

Also Published As

Publication number Publication date
KR100810699B1 (ko) 2008-03-07
WO2000031115A1 (en) 2000-06-02
KR20010081018A (ko) 2001-08-25
HUP0104519A3 (en) 2004-10-28
US6759516B2 (en) 2004-07-06
AUPP727398A0 (en) 1998-12-17
ZA200103677B (en) 2002-05-07
BR9915066A (pt) 2002-01-15
US20020068289A1 (en) 2002-06-06
NZ511623A (en) 2003-04-29
CA2351736A1 (en) 2000-06-02
MXPA01005011A (es) 2002-04-24
CN1331699A (zh) 2002-01-16
JP2002535604A (ja) 2002-10-22
EP1140978A4 (en) 2006-03-01
EP1140978A1 (en) 2001-10-10

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