HUP0104519A2 - Eljárások antigén-szekvenciák azonosítására - Google Patents
Eljárások antigén-szekvenciák azonosításáraInfo
- Publication number
- HUP0104519A2 HUP0104519A2 HU0104519A HUP0104519A HUP0104519A2 HU P0104519 A2 HUP0104519 A2 HU P0104519A2 HU 0104519 A HU0104519 A HU 0104519A HU P0104519 A HUP0104519 A HU P0104519A HU P0104519 A2 HUP0104519 A2 HU P0104519A2
- Authority
- HU
- Hungary
- Prior art keywords
- gene sequences
- subject
- nucleotide sequence
- methods
- expression
- Prior art date
Links
- 108091007433 antigens Proteins 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 7
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 230000000890 antigenic effect Effects 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 239000003550 marker Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000204031 Mycoplasma Species 0.000 abstract 1
- 241000204045 Mycoplasma hyopneumoniae Species 0.000 abstract 1
- 230000004186 co-expression Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000014509 gene expression Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A találmány tárgyát potenciális vakcinaantigének génszekvenciáinakazonosítására szolgáló eljárások képezik. A találmány tárgyát képeziktehát a génszekvenciák és a génszekvenciák által kódolt polipeptidek,illetve az ilyen szekvenciák alkalmazása védekező immunválaszindukálására állatokban. Konkrétan, a találmány tárgya Mycoplasma,<>előnyösen Mycoplasma hyopneumoniae potenciális antigéngénszekvenciáinak azonosítása. A találmány egy szempontja szerint a találmány tárgyát olyaneljárás képezi, amellyel expressziós vektorban lévőnukleotidszekvenciáról transzlálódott expressziós proteineket mutatunkki, és amely eljárás a nukleotidszekvenciából transzlálódott proteinés valamilyen marker együttes expressziójának alkalmazásáttartalmazza. A találmány egy másik szempontja szerint a találmánytárgya eljárás valamely betegség terápiás szempontból figyelembevehető, antigén tulajdonságú proteinjét kódoló terápiás antigéngénszekvenciájának nukleotidszekvencia-mintából történő azonosítására.A marker előnyösen poli-His-toldalék. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP7273A AUPP727398A0 (en) | 1998-11-20 | 1998-11-20 | Methods of identifying antigen gene sequences |
PCT/AU1999/001035 WO2000031115A1 (en) | 1998-11-20 | 1999-11-19 | Methods of identifying antigen gene sequences |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0104519A2 true HUP0104519A2 (hu) | 2002-03-28 |
HUP0104519A3 HUP0104519A3 (en) | 2004-10-28 |
Family
ID=3811482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0104519A HUP0104519A3 (en) | 1998-11-20 | 1999-11-19 | Methods of indentifying antigen gene sequences |
Country Status (13)
Country | Link |
---|---|
US (1) | US6759516B2 (hu) |
EP (1) | EP1140978A4 (hu) |
JP (1) | JP2002535604A (hu) |
KR (1) | KR100810699B1 (hu) |
CN (1) | CN1331699A (hu) |
AU (1) | AUPP727398A0 (hu) |
BR (1) | BR9915066A (hu) |
CA (1) | CA2351736A1 (hu) |
HU (1) | HUP0104519A3 (hu) |
MX (1) | MXPA01005011A (hu) |
NZ (1) | NZ511623A (hu) |
WO (1) | WO2000031115A1 (hu) |
ZA (1) | ZA200103677B (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2436986A1 (en) * | 2001-02-07 | 2002-08-15 | Invitrogen Corporation | Ter sites and ter binding proteins |
SI1546357T1 (sl) | 2002-06-28 | 2013-10-30 | Iowa State University Research Foundation, Inc. | Imunogeni polipeptidi mycoplasma hyopneumoniae |
WO2006050571A1 (en) * | 2004-11-11 | 2006-05-18 | Queensland University Of Technology | Chlamydia antigens and uses thereof |
CN101851661B (zh) * | 2010-05-10 | 2015-09-09 | 其昌達生物高科技(上海)有限公司 | 非诊断目的的在a-peg-b列阵下加快检测支原体时间的方法 |
WO2015123728A1 (en) * | 2014-02-18 | 2015-08-27 | University Of Technology, Sydney | Mycoplasma surface proteins and uses thereof |
BR102014014727B1 (pt) * | 2014-06-16 | 2018-04-03 | Ouro Fino Saúde Animal Ltda | COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, GENE SINTÉTICO CODIFICANTE DO COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, COMPOSIÇÃO ANTIGÊNICA, PROCESSO DE OBTENÇÃO DE UM COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae |
WO2018078167A1 (en) * | 2016-10-31 | 2018-05-03 | Universität Zürich | Protein screening and detection method |
CN112979769B (zh) * | 2021-03-08 | 2023-01-31 | 珠海丽禾医疗诊断产品有限公司 | 一种氨基酸序列、蛋白质及其制备方法和应用 |
CN113185588A (zh) * | 2021-04-28 | 2021-07-30 | 华中农业大学 | 一种牛支原体MbovP701蛋白及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68925769T2 (de) * | 1988-06-29 | 1996-08-08 | Ml Technology Ventures | Rekombinantes hyopneumoniae Antigen und dessen Verwendung |
WO1993003157A1 (en) * | 1991-07-29 | 1993-02-18 | Dana Farber Cancer Institute | Plasmids for the rapid preparation of modified proteins |
US5703057A (en) * | 1995-04-07 | 1997-12-30 | Board Of Regents The University Of Texas System | Expression library immunization |
-
1998
- 1998-11-20 AU AUPP7273A patent/AUPP727398A0/en not_active Abandoned
-
1999
- 1999-11-19 BR BR9915066-2A patent/BR9915066A/pt not_active Application Discontinuation
- 1999-11-19 NZ NZ511623A patent/NZ511623A/xx unknown
- 1999-11-19 EP EP99957754A patent/EP1140978A4/en not_active Withdrawn
- 1999-11-19 HU HU0104519A patent/HUP0104519A3/hu unknown
- 1999-11-19 KR KR1020017006157A patent/KR100810699B1/ko not_active IP Right Cessation
- 1999-11-19 WO PCT/AU1999/001035 patent/WO2000031115A1/en active IP Right Grant
- 1999-11-19 CN CN99814733A patent/CN1331699A/zh active Pending
- 1999-11-19 MX MXPA01005011A patent/MXPA01005011A/es not_active IP Right Cessation
- 1999-11-19 CA CA002351736A patent/CA2351736A1/en not_active Abandoned
- 1999-11-19 JP JP2000583942A patent/JP2002535604A/ja active Pending
-
2001
- 2001-05-07 ZA ZA200103677A patent/ZA200103677B/en unknown
- 2001-05-21 US US09/861,451 patent/US6759516B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR100810699B1 (ko) | 2008-03-07 |
WO2000031115A1 (en) | 2000-06-02 |
KR20010081018A (ko) | 2001-08-25 |
HUP0104519A3 (en) | 2004-10-28 |
US6759516B2 (en) | 2004-07-06 |
AUPP727398A0 (en) | 1998-12-17 |
ZA200103677B (en) | 2002-05-07 |
BR9915066A (pt) | 2002-01-15 |
US20020068289A1 (en) | 2002-06-06 |
NZ511623A (en) | 2003-04-29 |
CA2351736A1 (en) | 2000-06-02 |
MXPA01005011A (es) | 2002-04-24 |
CN1331699A (zh) | 2002-01-16 |
JP2002535604A (ja) | 2002-10-22 |
EP1140978A4 (en) | 2006-03-01 |
EP1140978A1 (en) | 2001-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |