HUP0103768A2 - Az APJ receptor és a HIV vírus közötti kölcsönhatás modulására vonatkozó eljárások és készítmények - Google Patents

Az APJ receptor és a HIV vírus közötti kölcsönhatás modulására vonatkozó eljárások és készítmények

Info

Publication number
HUP0103768A2
HUP0103768A2 HU0103768A HUP0103768A HUP0103768A2 HU P0103768 A2 HUP0103768 A2 HU P0103768A2 HU 0103768 A HU0103768 A HU 0103768A HU P0103768 A HUP0103768 A HU P0103768A HU P0103768 A2 HUP0103768 A2 HU P0103768A2
Authority
HU
Hungary
Prior art keywords
modulating
compositions
methods
hiv virus
apj receptor
Prior art date
Application number
HU0103768A
Other languages
English (en)
Inventor
Robert Doms
Daryl Faulds
Joseph E. Hesselgesser
Richard Horuk
Branislava Mitrovic
Yiqing Zhou
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of HUP0103768A2 publication Critical patent/HUP0103768A2/hu
Publication of HUP0103768A3 publication Critical patent/HUP0103768A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HU0103768A 1998-09-08 1999-09-07 Methods and compositions for modulating the interaction betwen the apj receptor and the hiv virus HUP0103768A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/149,045 US6475718B2 (en) 1998-09-08 1998-09-08 Methods and compositions for modulating the interaction between the APJ receptor and the HIV virus
PCT/EP1999/006553 WO2000014220A1 (en) 1998-09-08 1999-09-07 Methods and compositions for modulating the interaction between the apj receptor and the hiv virus

Publications (2)

Publication Number Publication Date
HUP0103768A2 true HUP0103768A2 (hu) 2002-02-28
HUP0103768A3 HUP0103768A3 (en) 2004-07-28

Family

ID=22528559

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103768A HUP0103768A3 (en) 1998-09-08 1999-09-07 Methods and compositions for modulating the interaction betwen the apj receptor and the hiv virus

Country Status (14)

Country Link
US (5) US6475718B2 (hu)
EP (1) EP1109906A1 (hu)
JP (1) JP2002532061A (hu)
KR (1) KR20020013467A (hu)
AU (1) AU767484B2 (hu)
BR (1) BR9913635A (hu)
CA (1) CA2341782A1 (hu)
HU (1) HUP0103768A3 (hu)
IL (1) IL141452A0 (hu)
NO (1) NO20011162L (hu)
PL (1) PL346564A1 (hu)
RU (1) RU2225721C2 (hu)
SK (1) SK3082001A3 (hu)
WO (1) WO2000014220A1 (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1419563A (zh) * 2000-03-23 2003-05-21 武田药品工业株式会社 肽衍生物
WO2001090123A2 (en) * 2000-05-23 2001-11-29 Genaissance Pharmaceuticals, Inc. Haplotypes of the agtrl1 gene
WO2006023893A2 (en) * 2004-08-23 2006-03-02 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for modulating angiogenesis and apoptosis with apelin compositions
EP3521311A1 (en) 2008-04-11 2019-08-07 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
RU2642318C2 (ru) 2010-11-30 2018-01-24 Чугаи Сейяку Кабусики Кайся Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
CN112812184A (zh) 2011-02-25 2021-05-18 中外制药株式会社 FcγRIIb特异性Fc抗体
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
WO2013047748A1 (ja) 2011-09-30 2013-04-04 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
TW201817745A (zh) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
US9309449B2 (en) * 2011-12-16 2016-04-12 Cargill, Incorporated Environmentally-friendly improved deicer compositions
EP2970415B1 (en) 2013-03-14 2018-12-19 Regeneron Pharmaceuticals, Inc. Apelin fusion proteins and uses thereof
CA2931299C (en) 2013-11-20 2024-03-05 Regeneron Pharmaceuticals, Inc. Aplnr modulators and uses thereof
SG11201700841QA (en) 2014-12-19 2017-03-30 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
LT3233921T (lt) 2014-12-19 2021-12-10 Chugai Seiyaku Kabushiki Kaisha Anti-c5 antikūnai ir panaudojimo būdai
WO2016125495A1 (en) 2015-02-05 2016-08-11 Chugai Seiyaku Kabushiki Kaisha Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
TWI759261B (zh) 2015-02-27 2022-04-01 日商中外製藥股份有限公司 Ｉｌ－６受體抗體用於製備醫藥組成物的用途
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
TWI693940B (zh) 2016-08-05 2020-05-21 日商中外製藥股份有限公司 Ｉｌ-８相關疾病之治療用或預防用組成物
US11608374B2 (en) 2017-01-30 2023-03-21 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3375697A (en) 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same

Also Published As

Publication number Publication date
SK3082001A3 (en) 2001-09-11
KR20020013467A (ko) 2002-02-20
US20020062488A1 (en) 2002-05-23
NO20011162D0 (no) 2001-03-07
US6475718B2 (en) 2002-11-05
BR9913635A (pt) 2001-05-22
HUP0103768A3 (en) 2004-07-28
EP1109906A1 (en) 2001-06-27
WO2000014220A1 (en) 2000-03-16
CA2341782A1 (en) 2000-03-16
US20030008279A1 (en) 2003-01-09
PL346564A1 (en) 2002-02-11
NO20011162L (no) 2001-03-07
US20030008376A1 (en) 2003-01-09
JP2002532061A (ja) 2002-10-02
US20030003447A1 (en) 2003-01-02
US20030008391A1 (en) 2003-01-09
IL141452A0 (en) 2002-03-10
RU2225721C2 (ru) 2004-03-20
AU767484B2 (en) 2003-11-13
AU5973799A (en) 2000-03-27

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