HUP0102099A3 - Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)ethyl]amides, process for producing them and pharmaceutical compositions containing them - Google Patents

Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)ethyl]amides, process for producing them and pharmaceutical compositions containing them

Info

Publication number
HUP0102099A3
HUP0102099A3 HU0102099A HUP0102099A HUP0102099A3 HU P0102099 A3 HUP0102099 A3 HU P0102099A3 HU 0102099 A HU0102099 A HU 0102099A HU P0102099 A HUP0102099 A HU P0102099A HU P0102099 A3 HUP0102099 A3 HU P0102099A3
Authority
HU
Hungary
Prior art keywords
indol
oxo
amides
ethyl
substituted
Prior art date
Application number
HU0102099A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HUP0102099A2 publication Critical patent/HUP0102099A2/hu
Publication of HUP0102099A3 publication Critical patent/HUP0102099A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
HU0102099A 1998-04-16 1999-04-03 Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)ethyl]amides, process for producing them and pharmaceutical compositions containing them HUP0102099A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19816780A DE19816780A1 (de) 1998-04-16 1998-04-16 Substituierte 2-Oxo-alkansäure-[2-(indol-3-yl)-ethyl]amide
PCT/EP1999/002302 WO1999054301A1 (de) 1998-04-16 1999-04-03 Substituierte 2-oxo-alkansäure-[2-(indol-3-yl)-ethyl]amide

Publications (2)

Publication Number Publication Date
HUP0102099A2 HUP0102099A2 (hu) 2001-11-28
HUP0102099A3 true HUP0102099A3 (en) 2001-12-28

Family

ID=7864659

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102099A HUP0102099A3 (en) 1998-04-16 1999-04-03 Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)ethyl]amides, process for producing them and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (1) US6255335B1 (hu)
EP (1) EP1071664A1 (hu)
JP (1) JP2002512226A (hu)
KR (1) KR20010052236A (hu)
CN (1) CN1297437A (hu)
AU (1) AU752273B2 (hu)
BR (1) BR9909692A (hu)
CA (1) CA2328875A1 (hu)
DE (1) DE19816780A1 (hu)
HU (1) HUP0102099A3 (hu)
WO (1) WO1999054301A1 (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102764D0 (sv) * 2001-08-17 2001-08-17 Astrazeneca Ab Compounds
GB0226930D0 (en) 2002-11-19 2002-12-24 Astrazeneca Ab Chemical compounds
KR20070007103A (ko) * 2004-02-18 2007-01-12 아스트라제네카 아베 벤즈아미드 유도체 및 이의 글루코키나아제 활성화제로서의용도
JP2007523905A (ja) * 2004-02-18 2007-08-23 アストラゼネカ アクチボラグ 化合物
TW200600086A (en) 2004-06-05 2006-01-01 Astrazeneca Ab Chemical compound
CA2581619A1 (en) * 2004-10-16 2006-04-20 Astrazeneca Ab Process for making phenoxy benzamide compounds
JP2008542247A (ja) * 2005-05-24 2008-11-27 アストラゼネカ アクチボラグ グルコキナーゼモジュレーターとしての2−フェニル置換イミダゾール[4,5b]ピリジン/ピラジンおよびプリン誘導体
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds
US20080234273A1 (en) * 2005-07-09 2008-09-25 Mckerrecher Darren Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes
JP4651714B2 (ja) * 2005-07-09 2011-03-16 アストラゼネカ アクチボラグ 糖尿病の治療においてglk活性化剤として使用するためのヘテロアリールベンズアミド誘導体
JP2009500442A (ja) * 2005-07-09 2009-01-08 アストラゼネカ アクチボラグ 2型糖尿病を処置するためのグルコキナーゼのモジュレーターとしての2−ヘテロシクリルオキシベンゾイルアミノヘテロシクリル化合物
US9202182B2 (en) * 2005-08-11 2015-12-01 International Business Machines Corporation Method and system for analyzing business architecture
TW200738621A (en) * 2005-11-28 2007-10-16 Astrazeneca Ab Chemical process
TW200825063A (en) * 2006-10-23 2008-06-16 Astrazeneca Ab Chemical compounds
TW200825060A (en) * 2006-10-26 2008-06-16 Astrazeneca Ab Chemical compounds
UY30822A1 (es) * 2006-12-21 2008-07-31 Astrazeneca Ab Fnueva forma cristalina de 3-{[5-azetidin-1-ylcabonyl)pyrazin-2-yl]oxy}-5-[1-methylethyloxy]-n-1h-pyrazol-3-ylbenzamida, composiciones conteniéndola, procesos de preparacion y aplicaciones
BRPI0917589A2 (pt) 2008-08-04 2015-11-17 Astrazeneca Ab composto, composição farmacêutica, uso de um composto, método para tratar doenças, processo, combinação farmacêutica, e, reação de metiloxirano-2-carboxilato (ix) com um álcool roh
GB0902406D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Crystalline polymorphic form
GB0902434D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Chemical process
WO2010116176A1 (en) * 2009-04-09 2010-10-14 Astrazeneca Ab Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity
WO2010116177A1 (en) 2009-04-09 2010-10-14 Astrazeneca Ab A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3217011A (en) 1965-05-07 1965-11-09 Sterling Drug Inc 1-(indolyglyoxalyl)-piperidines
US5569668A (en) 1995-03-29 1996-10-29 Webster; John M. Indole derivatives with antibacterial and antimycotic properties

Also Published As

Publication number Publication date
EP1071664A1 (de) 2001-01-31
JP2002512226A (ja) 2002-04-23
WO1999054301A1 (de) 1999-10-28
AU752273B2 (en) 2002-09-12
US6255335B1 (en) 2001-07-03
CA2328875A1 (en) 1999-10-28
BR9909692A (pt) 2000-12-19
DE19816780A1 (de) 1999-10-21
AU3605099A (en) 1999-11-08
HUP0102099A2 (hu) 2001-11-28
CN1297437A (zh) 2001-05-30
KR20010052236A (ko) 2001-06-25

Similar Documents

Publication Publication Date Title
HUP0102099A3 (en) Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)ethyl]amides, process for producing them and pharmaceutical compositions containing them
HUP0100723A3 (en) Indole derivatives, process for producing them and pharmaceutical compositions containing them
HUP0101599A3 (en) Heterocyclically substituted amides, process for producing them, use of them and pharmaceutical compositions containing them
HUP0001539A3 (en) 2-(1-iminoethylamino)ethyl-homocysteine, process for its preparation and pharmaceutical compositions containing the same
HUP0000323A3 (en) N-substituted 2-cyanopyrrolidine derivatives, process for producing them and pharmaceutical compositions containing them
HK1028769A1 (en) 2-aryl-8-oxodihydropurine derivatives, process for producing the same, medicinal compositions containing the same, and intermediates thereof
HUP0000748A3 (en) 4-phenyl-piridine derivatives, process for producing them and pharmaceutical compositions containing them
HU9402232D0 (en) 1-benzene-sulfonyl-1,3-dihydro-indol-2-one derivatives, process for producing them and pharmaceutical compositions containing them
HUP0004334A2 (en) Substituted 1,2,3,4-tetrahydronaphthalene derivatives, process for producing them and pharmaceutical compositions containing them
HUP9701265A3 (en) Imidazoline derivatives, process for producing them and pharmaceutical compositions containing them
HUP9802653A3 (en) Substituted imidazolidine derivatives, process for producing them, and pharmaceutical compositions containing them
HUP0105108A3 (en) Amide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0002057A3 (en) Indazole amide compounds, process for producing them, pharmaceutical compositions containing them and their intermediers
HUP0000088A3 (en) N-substituted azaheterocyclic compounds, process for producing them and pharmaceutical compositions containing them
HUP9901739A3 (en) Aminoisoquinolines and aminothienopyridine derivatives, process for producing thereof and pharmaceutical compositions containing them
HUP0102922A3 (en) 2,3-substituted indole compounds as cox-2 inhibitors, process for producing them and pharmaceutical compositions containing them
HUP0100760A3 (en) 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives, process for producing them and pharmaceutical compositions containing them
HUP9802121A3 (en) Imidazoline derivatives, process for producing them and pharmaceutical compositions containing them
HUP9901473A3 (en) 2,3-benzodiazepine derivatives, process for producing them and pharmaceutical compositions containing them
HUP0001522A3 (en) Benzoimidazole derivatives, process for producing them and pharmaceutical compositions containing them
HUP0202736A3 (en) Substituted aromatic-ring compounds, process for producing the same, and pharmaceutical compositions containing them and use thereof
HUP9701561A3 (en) N-acylated piperidine derivatives, process for producing them, and pharmaceutical compositions containing them
HUP9801950A3 (en) 2-(arylphenyl-amino)-imidazoline derivatives, process for producing them and pharmaceutical compositions containing them
HUP0105479A3 (en) Betha-alanine derivatives, process for producing them and pharmaceutical compositions containing them
HUP0202433A3 (en) Substituted pyrrolidin-2,3,4-trion-3-oxime derivatives useful as nmda-receptor antagonists, process for producing them and pharmaceutical compositions containing them