HUP0101415A2 - 3,7-Diaza-biciklo-[3.3.1] nonán-3-karboxilát sói, ezeket tartalmazó gyógyszerkészítmények, eljárás előállításukra és alkalmazásuk - Google Patents

3,7-Diaza-biciklo-[3.3.1] nonán-3-karboxilát sói, ezeket tartalmazó gyógyszerkészítmények, eljárás előállításukra és alkalmazásuk

Info

Publication number
HUP0101415A2
HUP0101415A2 HU0101415A HUP0101415A HUP0101415A2 HU P0101415 A2 HUP0101415 A2 HU P0101415A2 HU 0101415 A HU0101415 A HU 0101415A HU P0101415 A HUP0101415 A HU P0101415A HU P0101415 A2 HUP0101415 A2 HU P0101415A2
Authority
HU
Hungary
Prior art keywords
nonane
diazabicyclo
methods
carboxylic acid
acid salts
Prior art date
Application number
HU0101415A
Other languages
English (en)
Inventor
Annika Björe
Anna-Karin Granath
Original Assignee
Astrazeneca Ab,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, filed Critical Astrazeneca Ab,
Publication of HUP0101415A2 publication Critical patent/HUP0101415A2/hu
Publication of HUP0101415A3 publication Critical patent/HUP0101415A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány a terc-butil-{7-[(2S)-3-(4-cianofenoxi)-2-hidroxipropil]-3,7-diazabiciklo-[3.3.1]nonán-3-karboxilát} - sóira[(A) általánosképletű vegyület] vonatkozik. A találmány tárgyát képezik még az (A)általános képletű vegyület sóit tartalmazó gyógyszerkészítmények, az(A) általános képletű vegyület sóinak és a gyógyszerkészítményekelőállítására szolgáló eljárások, valamint a gyógyszerkészítményekszívritmuszavarok megelőzésére és/vagy kezelésére való alkalmazása. Ó
HU0101415A 1998-10-15 1999-10-11 3,7-diazabicyclo [3.3.1]-nonane-carboxylic acid salts, pharmaceutical preparation containing thereof, methods for their preparation and their use HUP0101415A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9803517A SE9803517D0 (sv) 1998-10-15 1998-10-15 Pharmaceutical preparation
PCT/SE1999/001828 WO2000021533A1 (en) 1998-10-15 1999-10-11 A dried or frozen pharmaceutical preparation containing a class iii antiarrhythmic compound

Publications (2)

Publication Number Publication Date
HUP0101415A2 true HUP0101415A2 (hu) 2001-11-28
HUP0101415A3 HUP0101415A3 (en) 2001-12-28

Family

ID=20412957

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101415A HUP0101415A3 (en) 1998-10-15 1999-10-11 3,7-diazabicyclo [3.3.1]-nonane-carboxylic acid salts, pharmaceutical preparation containing thereof, methods for their preparation and their use

Country Status (20)

Country Link
US (1) US6492382B1 (hu)
EP (1) EP1043997A1 (hu)
JP (1) JP2002527394A (hu)
KR (1) KR20010033104A (hu)
CN (1) CN1290167A (hu)
AU (1) AU1424100A (hu)
BR (1) BR9906869A (hu)
CA (1) CA2315375A1 (hu)
EE (1) EE200000354A (hu)
HU (1) HUP0101415A3 (hu)
IL (1) IL136428A0 (hu)
IS (1) IS5529A (hu)
NO (1) NO20002986D0 (hu)
PL (1) PL341384A1 (hu)
SA (1) SA99200678A (hu)
SE (1) SE9803517D0 (hu)
SK (1) SK8192000A3 (hu)
TR (1) TR200001760T1 (hu)
WO (1) WO2000021533A1 (hu)
ZA (1) ZA200002749B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9803517D0 (sv) 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation
SE9902270D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
EP1638523B8 (en) * 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
CN102026621A (zh) * 2008-05-15 2011-04-20 巴克斯特国际公司 稳定的药物制剂
EP2149370A1 (en) * 2008-07-31 2010-02-03 Neuroscienze Pharmaness S.C. A R.L. Diazabicyclic compounds and microemulsions thereof
US20220062213A1 (en) * 2020-09-02 2022-03-03 Jubilant Pharma Holdings Inc. Methods and compositions of solabegron for reducing body fat
US20220062288A1 (en) * 2020-09-02 2022-03-03 Jubilant Pharma Holdings Inc. Pharmaceutical compositions of vibegron for reducing body fat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950010150B1 (ko) 1986-01-14 1995-09-11 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 함유 주사제의 안정화 방법
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9803517D0 (sv) 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation

Also Published As

Publication number Publication date
US6492382B1 (en) 2002-12-10
EE200000354A (et) 2001-12-17
AU1424100A (en) 2000-05-01
PL341384A1 (en) 2001-04-09
JP2002527394A (ja) 2002-08-27
BR9906869A (pt) 2000-10-17
SK8192000A3 (en) 2001-02-12
IL136428A0 (en) 2001-06-14
WO2000021533A1 (en) 2000-04-20
SE9803517D0 (sv) 1998-10-15
NO20002986L (no) 2000-06-09
SA99200678A (ar) 2005-12-03
EP1043997A1 (en) 2000-10-18
ZA200002749B (en) 2001-01-11
IS5529A (is) 2000-06-13
CN1290167A (zh) 2001-04-04
TR200001760T1 (tr) 2000-11-21
KR20010033104A (ko) 2001-04-25
CA2315375A1 (en) 2000-04-20
NO20002986D0 (no) 2000-06-09
HUP0101415A3 (en) 2001-12-28

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