HUP0100126A2 - Előaktivált kiméra transzkripciós faktorok - Google Patents

Előaktivált kiméra transzkripciós faktorok

Info

Publication number
HUP0100126A2
HUP0100126A2 HU0100126A HUP0100126A HUP0100126A2 HU P0100126 A2 HUP0100126 A2 HU P0100126A2 HU 0100126 A HU0100126 A HU 0100126A HU P0100126 A HUP0100126 A HU P0100126A HU P0100126 A2 HUP0100126 A2 HU P0100126A2
Authority
HU
Hungary
Prior art keywords
transcription factors
activated transcription
production
chimeric pre
chimeric
Prior art date
Application number
HU0100126A
Other languages
English (en)
Inventor
Gerald R. Fink
Peter Hecht
Kevin Madden
Original Assignee
Microbia, Inc.
Whitehead Institute For Biomedical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbia, Inc., Whitehead Institute For Biomedical Research filed Critical Microbia, Inc.
Publication of HUP0100126A2 publication Critical patent/HUP0100126A2/hu
Publication of HUP0100126A3 publication Critical patent/HUP0100126A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány tárgyát előaktivált transzkripciós faktortés gomba-génexpressziót szabályozó erős transzkripciós aktivációsdomént tartalmazó kiméra proteinek képezik, valamint a találmányszerinti proteinek előállítására és alkalmazására szolgáló eljárásokés reagensek. A találmány szerinti megoldás alkalmas gombák genetikaimanipulációs módosítására, többek között szekunder metabolitokelőállítása céljából. Ó
HU0100126A 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors HUP0100126A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6612997P 1997-11-19 1997-11-19
US6630897P 1997-11-21 1997-11-21
US6646297P 1997-11-24 1997-11-24
PCT/US1998/024975 WO1999025735A1 (en) 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors

Publications (2)

Publication Number Publication Date
HUP0100126A2 true HUP0100126A2 (hu) 2001-05-28
HUP0100126A3 HUP0100126A3 (en) 2003-03-28

Family

ID=27370919

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100126A HUP0100126A3 (en) 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors

Country Status (9)

Country Link
US (1) US6500636B1 (hu)
EP (1) EP1032590A4 (hu)
JP (1) JP2002505072A (hu)
KR (1) KR20010032246A (hu)
AU (1) AU762910B2 (hu)
CA (1) CA2310624A1 (hu)
CZ (1) CZ20001841A3 (hu)
HU (1) HUP0100126A3 (hu)
WO (1) WO1999025735A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299850B1 (en) * 1999-03-16 2001-10-09 The United States Of America As Represented By The Department Of Energy Carbon activation process for increased surface accessibility in electrochemical capacitors
US6949356B1 (en) * 1999-10-20 2005-09-27 Microbia, Inc. Methods for improving secondary metabolite production in fungi
ES2164574B1 (es) * 1999-12-10 2003-05-16 Consejo Superior Investigacion Mejora de la produccion de penicilina mediante la utilizacion de cepas transgenicas merodiploides para un gen regulador.
HUP0300469A2 (hu) * 2000-04-13 2003-06-28 Emalfarb, Mark Aaron Új, expressziós szabályzó szekvenciák és expressziós termékek fonalas gombákban
US6806082B2 (en) 2000-12-22 2004-10-19 Microbia, Inc. Isolated nucleic acid molecule encoding a regulator of fungal gene expression
GB0424940D0 (en) * 2004-11-11 2004-12-15 Danisco Transcription factors
EP4269427A3 (en) 2016-05-27 2023-11-22 Synthex, Inc. Protein interfaces
GB2584210B (en) 2017-11-22 2022-03-16 Synthex Inc Peptides for inhibiting RAD51

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104264B (fi) 1988-08-11 1999-12-15 Dsm Ip Assets Bv Menetelmä sekundääristen metaboliittien tuoton parantamiseksi käyttämällä rykelmöityjä biosynteettisiä geenejä
US5589362A (en) * 1993-06-14 1996-12-31 Basf Aktiengesellschaft Tetracycline regulated transcriptional modulators with altered DNA binding specificities
US6015709A (en) 1997-08-26 2000-01-18 Ariad Pharmaceuticals, Inc. Transcriptional activators, and compositions and uses related thereto

Also Published As

Publication number Publication date
JP2002505072A (ja) 2002-02-19
CZ20001841A3 (cs) 2001-09-12
CA2310624A1 (en) 1999-05-27
KR20010032246A (ko) 2001-04-16
EP1032590A1 (en) 2000-09-06
AU1797999A (en) 1999-06-07
US6500636B1 (en) 2002-12-31
AU762910B2 (en) 2003-07-10
EP1032590A4 (en) 2005-04-06
WO1999025735A1 (en) 1999-05-27
HUP0100126A3 (en) 2003-03-28

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