HUP0100126A2 - Előaktivált kiméra transzkripciós faktorok - Google Patents

Előaktivált kiméra transzkripciós faktorok

Info

Publication number
HUP0100126A2
HUP0100126A2 HU0100126A HUP0100126A HUP0100126A2 HU P0100126 A2 HUP0100126 A2 HU P0100126A2 HU 0100126 A HU0100126 A HU 0100126A HU P0100126 A HUP0100126 A HU P0100126A HU P0100126 A2 HUP0100126 A2 HU P0100126A2
Authority
HU
Hungary
Prior art keywords
transcription factors
activated transcription
production
chimeric pre
chimeric
Prior art date
Application number
HU0100126A
Other languages
English (en)
Inventor
Gerald R. Fink
Peter Hecht
Kevin Madden
Original Assignee
Microbia, Inc.
Whitehead Institute For Biomedical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbia, Inc., Whitehead Institute For Biomedical Research filed Critical Microbia, Inc.
Publication of HUP0100126A2 publication Critical patent/HUP0100126A2/hu
Publication of HUP0100126A3 publication Critical patent/HUP0100126A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány tárgyát előaktivált transzkripciós faktortés gomba-génexpressziót szabályozó erős transzkripciós aktivációsdomént tartalmazó kiméra proteinek képezik, valamint a találmányszerinti proteinek előállítására és alkalmazására szolgáló eljárásokés reagensek. A találmány szerinti megoldás alkalmas gombák genetikaimanipulációs módosítására, többek között szekunder metabolitokelőállítása céljából. Ó
HU0100126A 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors HUP0100126A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6612997P 1997-11-19 1997-11-19
US6630897P 1997-11-21 1997-11-21
US6646297P 1997-11-24 1997-11-24
PCT/US1998/024975 WO1999025735A1 (en) 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors

Publications (2)

Publication Number Publication Date
HUP0100126A2 true HUP0100126A2 (hu) 2001-05-28
HUP0100126A3 HUP0100126A3 (en) 2003-03-28

Family

ID=27370919

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100126A HUP0100126A3 (en) 1997-11-19 1998-11-19 Chimeric pre-activated transcription factors

Country Status (9)

Country Link
US (1) US6500636B1 (hu)
EP (1) EP1032590A4 (hu)
JP (1) JP2002505072A (hu)
KR (1) KR20010032246A (hu)
AU (1) AU762910B2 (hu)
CA (1) CA2310624A1 (hu)
CZ (1) CZ20001841A3 (hu)
HU (1) HUP0100126A3 (hu)
WO (1) WO1999025735A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299850B1 (en) * 1999-03-16 2001-10-09 The United States Of America As Represented By The Department Of Energy Carbon activation process for increased surface accessibility in electrochemical capacitors
US6949356B1 (en) * 1999-10-20 2005-09-27 Microbia, Inc. Methods for improving secondary metabolite production in fungi
ES2164574B1 (es) * 1999-12-10 2003-05-16 Consejo Superior Investigacion Mejora de la produccion de penicilina mediante la utilizacion de cepas transgenicas merodiploides para un gen regulador.
HUP0300469A2 (hu) * 2000-04-13 2003-06-28 Emalfarb, Mark Aaron Új, expressziós szabályzó szekvenciák és expressziós termékek fonalas gombákban
US6806082B2 (en) 2000-12-22 2004-10-19 Microbia, Inc. Isolated nucleic acid molecule encoding a regulator of fungal gene expression
GB0424940D0 (en) * 2004-11-11 2004-12-15 Danisco Transcription factors
EP4269427A3 (en) 2016-05-27 2023-11-22 Synthex, Inc. Protein interfaces
GB2584210B (en) 2017-11-22 2022-03-16 Synthex Inc Peptides for inhibiting RAD51

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104264B (fi) 1988-08-11 1999-12-15 Dsm Ip Assets Bv Menetelmä sekundääristen metaboliittien tuoton parantamiseksi käyttämällä rykelmöityjä biosynteettisiä geenejä
US5589362A (en) * 1993-06-14 1996-12-31 Basf Aktiengesellschaft Tetracycline regulated transcriptional modulators with altered DNA binding specificities
US6015709A (en) 1997-08-26 2000-01-18 Ariad Pharmaceuticals, Inc. Transcriptional activators, and compositions and uses related thereto

Also Published As

Publication number Publication date
JP2002505072A (ja) 2002-02-19
CZ20001841A3 (cs) 2001-09-12
CA2310624A1 (en) 1999-05-27
KR20010032246A (ko) 2001-04-16
EP1032590A1 (en) 2000-09-06
AU1797999A (en) 1999-06-07
US6500636B1 (en) 2002-12-31
AU762910B2 (en) 2003-07-10
EP1032590A4 (en) 2005-04-06
WO1999025735A1 (en) 1999-05-27
HUP0100126A3 (en) 2003-03-28

Similar Documents

Publication Publication Date Title
EP1239049A3 (de) Wasserstofperoxid Bestimmung mittels Oxidasen und Lanthanoid-Liganden-Komplexen
ATE309536T1 (de) Methoden zur verwendung von randomisierten zinkfingerprotein-bibliotheken zur identifizierung von genfunktionen
ATE514783T1 (de) Plasmidsystem zur expression mehrerer gene
ES2186690T3 (es) Acido nucleico enzimatico que contiene no-nucleotidos.
ATE310812T1 (de) Derivate von zinkfingerproteinen und methoden
EP1092771A3 (en) Tetracycline-regulated transcriptional modulators
WO2003000038A3 (en) Compositions and methods for modulating plant development
WO2001038532A3 (en) Reagents and methods for identifying and modulating expression of genes regulated by cdk inhibitors
HUP0100126A2 (hu) Előaktivált kiméra transzkripciós faktorok
DE60042209D1 (de) Enzymatische synthese von deoxyribonucleotiden
DE59712319D1 (de) Genfallen-konstrukt zur identifizierung und isolierung von genen
DE60118798D1 (de) Fragmente der intron a von citomegalovirus
DE69534685D1 (de) Transferase und amylase, verfahren zur herstellung dieser enzyme, ihre verwendung und für die kodierende gene
AU2002361797A1 (en) Cell lines with latent immunodeficiency virus and methods of use thereof
ATE427959T1 (de) Gereinigtes sr-p70 protein
MY132553A (en) Methods of making hiv-protease inhibitors and intermediates for making hiv-protease inhibitors
WO2000061729A3 (en) Regulation of the expression of transcriptional repressor genes using nucleic acid molecules
DK1058739T3 (da) Fremgangsmåde til dannelse af genekspressionsprofiler
ATE286908T1 (de) Gewebespezifische expression des retinoblastoma- proteins
DE60210970D1 (de) Mutante formen von etxb und ctxb und ihre verwendung als träger
HUP0001048A2 (hu) Új vegyületek
AU1539801A (en) Transcription factors containing two potential dna binding motifs
DE69813468D1 (de) Bauteilsatz für die Herstellung von vorgesteuerten Gasdruckreglern
WO2002029101A3 (en) Methods for cloning, sequencing and expressing genes from complex microbial populations
AU2003903132A0 (en) Plant promoter