HUP0003038A2 - Kis dózisban adagolható 15-dezoxi-szperkvalin készítmények - Google Patents

Kis dózisban adagolható 15-dezoxi-szperkvalin készítmények

Info

Publication number
HUP0003038A2
HUP0003038A2 HU0003038A HUP0003038A HUP0003038A2 HU P0003038 A2 HUP0003038 A2 HU P0003038A2 HU 0003038 A HU0003038 A HU 0003038A HU P0003038 A HUP0003038 A HU P0003038A HU P0003038 A2 HUP0003038 A2 HU P0003038A2
Authority
HU
Hungary
Prior art keywords
preparations
desoxyspergualine
sperqualin
deoxy
inflammatory
Prior art date
Application number
HU0003038A
Other languages
English (en)
Inventor
Niels Franke
Original Assignee
Niels Franke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Niels Franke filed Critical Niels Franke
Publication of HUP0003038A2 publication Critical patent/HUP0003038A2/hu
Publication of HUP0003038A3 publication Critical patent/HUP0003038A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Atalálmány tárgya 15-dezoxi-szperkvalin alkalmazása immunszuppresszív,gyulladásgátló és tumorellenes hatású, különösen autoimmunmegbetegedések, gyulladásos bőrbetegségek, rákos megbetegedések ellenhatásos és transzplantátumok kilökődését gátló gyógyszerkészítményekelőállítására, amelyek a nyálkahártyán át, napi 20-600mg/testtömegkilogramm dózisban adagolhatók. Ahatóanyag aH2NC(=NH)NH(CH2)8CONHCH(OH)CONH(CH2)4NH(CH2)3NH2<3HCl képletű (<)-15-dezoxi-szperkvalin, amely a tumorellenes hatású szperkvalinantibiotikum szintetikus származéka. Ó
HU0003038A 1997-07-03 1998-06-26 Low dosed 15-desoxyspergualine preparations HUP0003038A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19728436A DE19728436A1 (de) 1997-07-03 1997-07-03 Niedrigdosierte 15-Desoxyspergualin-Präparate

Publications (2)

Publication Number Publication Date
HUP0003038A2 true HUP0003038A2 (hu) 2001-01-29
HUP0003038A3 HUP0003038A3 (en) 2003-05-28

Family

ID=7834537

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003038A HUP0003038A3 (en) 1997-07-03 1998-06-26 Low dosed 15-desoxyspergualine preparations

Country Status (10)

Country Link
US (1) US6166087A (hu)
EP (1) EP1001753A1 (hu)
JP (1) JP2002507221A (hu)
AU (1) AU8801498A (hu)
CA (1) CA2294785A1 (hu)
DE (2) DE19728436A1 (hu)
HU (1) HUP0003038A3 (hu)
PL (1) PL337802A1 (hu)
TR (1) TR199903322T2 (hu)
WO (1) WO1999001123A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19923961A1 (de) 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0211514A (ja) * 1988-06-30 1990-01-16 Takara Shuzo Co Ltd スパガリン類製剤
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
DE69129459T2 (de) * 1990-08-10 1998-10-15 Anormed Inc Immunosuppressive zusammensetzungen
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
DE4417816A1 (de) * 1994-05-20 1995-11-23 Franke Niels Prof Dr Mittel zur Aufrechterhaltung und/oder Steigerung der Funktionalität von Haut
WO1996024579A1 (fr) * 1995-02-10 1996-08-15 Fournier Industrie Et Sante Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation

Also Published As

Publication number Publication date
JP2002507221A (ja) 2002-03-05
HUP0003038A3 (en) 2003-05-28
PL337802A1 (en) 2000-09-11
CA2294785A1 (en) 1999-01-14
AU8801498A (en) 1999-01-25
EP1001753A1 (de) 2000-05-24
WO1999001123A1 (de) 1999-01-14
DE19728436A1 (de) 1999-01-07
US6166087A (en) 2000-12-26
DE19880842D2 (de) 2000-11-30
TR199903322T2 (xx) 2000-09-21

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