HUE072309T2 - Piridinilszubsztituált oxoizoindolin vegyületek - Google Patents

Piridinilszubsztituált oxoizoindolin vegyületek

Info

Publication number
HUE072309T2
HUE072309T2 HUE22718513A HUE22718513A HUE072309T2 HU E072309 T2 HUE072309 T2 HU E072309T2 HU E22718513 A HUE22718513 A HU E22718513A HU E22718513 A HUE22718513 A HU E22718513A HU E072309 T2 HUE072309 T2 HU E072309T2
Authority
HU
Hungary
Prior art keywords
oxoisoindoline
compounds
pyridinyl substituted
pyridinyl
substituted
Prior art date
Application number
HUE22718513A
Other languages
English (en)
Hungarian (hu)
Inventor
Yan Chen
Godwin Kwame Kumi
Audris Huang
Satheesh Kesavan Nair
Bharat Dinkar Shimpukade
Suresh Babu Vishwa Krishna Penmetsa
James Aaron Balog
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HUE072309T2 publication Critical patent/HUE072309T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
HUE22718513A 2021-04-06 2022-04-05 Piridinilszubsztituált oxoizoindolin vegyületek HUE072309T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202111016193 2021-04-06
IN202111022098 2021-05-17

Publications (1)

Publication Number Publication Date
HUE072309T2 true HUE072309T2 (hu) 2025-11-28

Family

ID=81385129

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE22718513A HUE072309T2 (hu) 2021-04-06 2022-04-05 Piridinilszubsztituált oxoizoindolin vegyületek

Country Status (26)

Country Link
US (3) US11718601B2 (enExample)
EP (1) EP4320112B1 (enExample)
JP (1) JP7821197B2 (enExample)
KR (1) KR20230165815A (enExample)
AR (1) AR125298A1 (enExample)
AU (1) AU2022253242A1 (enExample)
BR (1) BR112023020077A2 (enExample)
CA (1) CA3214244A1 (enExample)
CL (1) CL2023002966A1 (enExample)
CO (1) CO2023013321A2 (enExample)
DK (1) DK4320112T3 (enExample)
ES (1) ES3035755T3 (enExample)
FI (1) FI4320112T3 (enExample)
HR (1) HRP20250796T1 (enExample)
HU (1) HUE072309T2 (enExample)
IL (1) IL307343A (enExample)
LT (1) LT4320112T (enExample)
MX (1) MX2023011715A (enExample)
PE (1) PE20231941A1 (enExample)
PL (1) PL4320112T3 (enExample)
PT (1) PT4320112T (enExample)
RS (1) RS66982B1 (enExample)
SI (1) SI4320112T1 (enExample)
SM (1) SMT202500281T1 (enExample)
TW (1) TWI867287B (enExample)
WO (1) WO2022216644A1 (enExample)

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CN118488948A (zh) 2021-12-22 2024-08-13 吉利德科学公司 Ikaros锌指家族降解剂及其用途
PL4245756T3 (pl) 2022-03-17 2025-02-17 Gilead Sciences, Inc. Środki degradujące palec cynkowy z rodziny ikaros i ich zastosowania
CN120677149A (zh) * 2023-02-08 2025-09-19 细胞基因公司 用于选择性降解工程化蛋白的化合物和组合物
CN121752560A (zh) 2023-09-02 2026-03-27 百时美施贵宝公司 经取代的苯基氧代噁唑基哌啶二酮化合物
JP7901265B2 (ja) 2024-03-22 2026-08-05 ブリストル-マイヤーズ スクイブ カンパニー 新規fak分解化合物およびその使用
WO2025226767A1 (en) * 2024-04-24 2025-10-30 Bristol-Myers Squibb Company Substituted 3-(5-(6-aminopyridin-2-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione compounds for use in the treatment of cancer
WO2025234888A1 (en) 2024-05-09 2025-11-13 Captor Therapeutics S.A. Nek7 degraders and methods of use thereof
WO2025234887A1 (en) 2024-05-09 2025-11-13 Captor Therapeutics S.A. Nek7 degraders and methods of use thereof

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Also Published As

Publication number Publication date
JP7821197B2 (ja) 2026-02-26
CL2023002966A1 (es) 2024-02-23
AU2022253242A1 (en) 2023-11-23
SMT202500281T1 (it) 2025-09-12
WO2022216644A1 (en) 2022-10-13
MX2023011715A (es) 2023-10-12
PE20231941A1 (es) 2023-12-05
US20230303527A1 (en) 2023-09-28
IL307343A (en) 2023-11-01
EP4320112A1 (en) 2024-02-14
RS66982B1 (sr) 2025-07-31
TW202304881A (zh) 2023-02-01
CA3214244A1 (en) 2022-10-13
AR125298A1 (es) 2023-07-05
SI4320112T1 (sl) 2025-09-30
DK4320112T3 (da) 2025-08-18
US11718601B2 (en) 2023-08-08
US20220324840A1 (en) 2022-10-13
KR20230165815A (ko) 2023-12-05
BR112023020077A2 (pt) 2023-11-14
US20240376082A1 (en) 2024-11-14
JP2024515243A (ja) 2024-04-08
PL4320112T3 (pl) 2025-07-21
EP4320112B1 (en) 2025-05-14
HRP20250796T1 (hr) 2025-08-29
LT4320112T (lt) 2025-07-10
CO2023013321A2 (es) 2023-10-19
PT4320112T (pt) 2025-07-07
TWI867287B (zh) 2024-12-21
FI4320112T3 (fi) 2025-07-25
ES3035755T3 (en) 2025-09-08

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