HUE064591T2 - T-sejt receptorok - Google Patents

T-sejt receptorok

Info

Publication number
HUE064591T2
HUE064591T2 HUE17715521A HUE17715521A HUE064591T2 HU E064591 T2 HUE064591 T2 HU E064591T2 HU E17715521 A HUE17715521 A HU E17715521A HU E17715521 A HUE17715521 A HU E17715521A HU E064591 T2 HUE064591 T2 HU E064591T2
Authority
HU
Hungary
Prior art keywords
cell receptors
receptors
cell
Prior art date
Application number
HUE17715521A
Other languages
English (en)
Inventor
Tara Mahon
Original Assignee
Immunocore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunocore Ltd filed Critical Immunocore Ltd
Publication of HUE064591T2 publication Critical patent/HUE064591T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
HUE17715521A 2016-03-23 2017-03-22 T-sejt receptorok HUE064591T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1604953.8A GB201604953D0 (en) 2016-03-23 2016-03-23 T cell receptors

Publications (1)

Publication Number Publication Date
HUE064591T2 true HUE064591T2 (hu) 2024-03-28

Family

ID=55968783

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17715521A HUE064591T2 (hu) 2016-03-23 2017-03-22 T-sejt receptorok

Country Status (20)

Country Link
US (2) US11440944B2 (hu)
EP (1) EP3433270B1 (hu)
JP (1) JP7051699B2 (hu)
CN (1) CN109563147A (hu)
AU (1) AU2017236415B2 (hu)
BR (1) BR112018069275A2 (hu)
CA (1) CA3018467A1 (hu)
DK (1) DK3433270T3 (hu)
ES (1) ES2965715T3 (hu)
FI (1) FI3433270T3 (hu)
GB (1) GB201604953D0 (hu)
HR (1) HRP20231645T1 (hu)
HU (1) HUE064591T2 (hu)
LT (1) LT3433270T (hu)
PL (1) PL3433270T3 (hu)
PT (1) PT3433270T (hu)
RS (1) RS64952B1 (hu)
SI (1) SI3433270T1 (hu)
SM (1) SMT202300448T1 (hu)
WO (1) WO2017163064A1 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111954679A (zh) 2017-10-03 2020-11-17 朱诺治疗学股份有限公司 Hpv特异性结合分子
EP3775237A1 (en) * 2018-04-05 2021-02-17 Juno Therapeutics, Inc. T cells expressing a recombinant receptor, related polynucleotides and methods
KR20210029707A (ko) * 2018-04-05 2021-03-16 주노 쎄러퓨티크스 인코퍼레이티드 재조합 수용체를 발현하는 세포의 생산 방법 및 관련 조성물
CA3126422A1 (en) * 2019-01-14 2020-07-23 Nanjing Legend Biotech Co., Ltd. Chimeric receptor polypeptides and uses thereof
GB201902277D0 (en) 2019-02-19 2019-04-03 King S College London Therapeutic agents
GB202010329D0 (en) * 2020-07-06 2020-08-19 Immunocore Ltd Specific binding molecules
US12103971B2 (en) 2022-02-20 2024-10-01 Immunocore Limited HIV specific binding molecules
WO2023156663A1 (en) 2022-02-20 2023-08-24 Immunocore Limited Hiv-specific binding molecules and tcr
CN120775790A (zh) * 2024-04-04 2025-10-14 香雪生命科学技术(广东)有限公司 一种分泌型效应细胞

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039482A1 (en) 1997-03-07 1998-09-11 Sunol Molecular Corporation Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor
EP1019439B1 (en) 1997-10-02 2011-11-16 Altor BioScience Corporation Soluble single-chain t-cell receptor proteins
MX340559B (es) 1999-12-06 2016-07-14 Board Of Trustees Of The Univ Of Illinois Proteinas de tcr de alta afinidad y metodos.
AU2001232204A1 (en) 2000-02-22 2001-09-03 Ahuva Nissim Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof
EP1421115B1 (en) 2001-08-31 2005-03-02 Avidex Limited Soluble t cell receptor
NZ539225A (en) 2002-10-09 2006-09-29 Avidex Ltd Single chain recombinant T cell receptors
ES2327229T3 (es) 2002-11-09 2009-10-27 Immunocore Ltd. Presentacion del receptor de linfocitos t.
EP2275441B8 (en) 2005-04-01 2016-10-19 Immunocore Ltd. High affinity HIV T cell receptors
WO2008038002A2 (en) 2006-09-29 2008-04-03 Medigene Limited T cell therapies
GB0908613D0 (en) 2009-05-20 2009-06-24 Immunocore Ltd T Cell Reseptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
GB201223172D0 (en) 2012-12-21 2013-02-06 Immunocore Ltd Method
CN106478807B (zh) * 2015-10-30 2018-06-01 广东香雪精准医疗技术有限公司 识别mage-a3的t细胞受体

Also Published As

Publication number Publication date
CA3018467A1 (en) 2017-09-28
JP2019512252A (ja) 2019-05-16
FI3433270T3 (fi) 2023-12-18
EP3433270A1 (en) 2019-01-30
PL3433270T3 (pl) 2024-03-04
SI3433270T1 (sl) 2023-11-30
LT3433270T (lt) 2023-10-25
US11440944B2 (en) 2022-09-13
CN109563147A (zh) 2019-04-02
AU2017236415B2 (en) 2023-05-11
SMT202300448T1 (it) 2024-05-14
RS64952B1 (sr) 2024-01-31
HRP20231645T1 (hr) 2024-03-15
US20190106475A1 (en) 2019-04-11
DK3433270T3 (da) 2023-12-11
EP3433270B1 (en) 2023-09-20
JP7051699B2 (ja) 2022-04-11
BR112018069275A2 (pt) 2019-01-22
AU2017236415A1 (en) 2018-11-15
PT3433270T (pt) 2023-12-22
ES2965715T3 (es) 2024-04-16
GB201604953D0 (en) 2016-05-04
US20230192806A1 (en) 2023-06-22
WO2017163064A1 (en) 2017-09-28

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