HUE062167T2 - Automatizált eljárás és berendezés bioeljárási oldatok elõállítására - Google Patents

Automatizált eljárás és berendezés bioeljárási oldatok elõállítására

Info

Publication number
HUE062167T2
HUE062167T2 HUE18747045A HUE18747045A HUE062167T2 HU E062167 T2 HUE062167 T2 HU E062167T2 HU E18747045 A HUE18747045 A HU E18747045A HU E18747045 A HUE18747045 A HU E18747045A HU E062167 T2 HUE062167 T2 HU E062167T2
Authority
HU
Hungary
Prior art keywords
preparing
automated method
bioprocess
solutions
bioprocess solutions
Prior art date
Application number
HUE18747045A
Other languages
English (en)
Inventor
Thomas Reid Fletcher
Wayne Mauro
David Neese
Original Assignee
Fujifilm Irvine Scient Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Irvine Scient Inc filed Critical Fujifilm Irvine Scient Inc
Publication of HUE062167T2 publication Critical patent/HUE062167T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M99/00Subject matter not otherwise provided for in other groups of this subclass
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/211Measuring of the operational parameters
    • B01F35/2111Flow rate
    • B01F35/21112Volumetric flow rate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00Dissolving
    • B01F21/30Workflow diagrams or layout of plants, e.g. flow charts; Details of workflow diagrams or layout of plants, e.g. controlling means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/49Mixing systems, i.e. flow charts or diagrams
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/80After-treatment of the mixture
    • B01F23/808Filtering the mixture
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/10Mixing by creating a vortex flow, e.g. by tangential introduction of flow components
    • B01F25/101Mixing by creating a vortex flow, e.g. by tangential introduction of flow components wherein the vortex flows in a spherical shaped receptacle or chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/10Mixing by creating a vortex flow, e.g. by tangential introduction of flow components
    • B01F25/102Mixing by creating a vortex flow, e.g. by tangential introduction of flow components wherein the vortex is created by two or more jets introduced tangentially in separate mixing chambers or consecutively in the same mixing chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30Injector mixers
    • B01F25/31Injector mixers in conduits or tubes through which the main component flows
    • B01F25/316Injector mixers in conduits or tubes through which the main component flows with containers for additional components fixed to the conduit
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/805Mixing plants; Combinations of mixers for granular material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/81Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/81Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/812Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more alternative mixing receptacles, e.g. mixing in one receptacle and dispensing from another receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/211Measuring of the operational parameters
    • B01F35/2111Flow rate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/211Measuring of the operational parameters
    • B01F35/2113Pressure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/2132Concentration, pH, pOH, p(ION) or oxygen-demand
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/2133Electrical conductivity or dielectric constant of the mixture
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/22Control or regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/02Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
HUE18747045A 2017-06-30 2018-06-25 Automatizált eljárás és berendezés bioeljárási oldatok elõállítására HUE062167T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762527878P 2017-06-30 2017-06-30

Publications (1)

Publication Number Publication Date
HUE062167T2 true HUE062167T2 (hu) 2023-10-28

Family

ID=63047430

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18747045A HUE062167T2 (hu) 2017-06-30 2018-06-25 Automatizált eljárás és berendezés bioeljárási oldatok elõállítására

Country Status (12)

Country Link
US (2) US11097237B2 (hu)
EP (2) EP3645699B1 (hu)
JP (2) JP7297687B2 (hu)
KR (1) KR102628933B1 (hu)
CN (1) CN111094529A (hu)
AU (1) AU2018292271B2 (hu)
CA (1) CA3068618A1 (hu)
DK (1) DK3645699T3 (hu)
ES (1) ES2943648T3 (hu)
HU (1) HUE062167T2 (hu)
SG (1) SG11201913149PA (hu)
WO (1) WO2019005664A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019209805A1 (en) * 2018-04-27 2019-10-31 Baxter International Inc. Method of mixing a pharmaceutical solution and mixing system
SG11202101676TA (en) 2018-08-31 2021-03-30 Fujifilm Irvine Scientific Inc Venting system for a mixing apparatus
CN115867636A (zh) * 2020-07-06 2023-03-28 默克专利股份公司 用于细胞培养基制备和进行细胞培养的装置和方法
US20240116016A1 (en) * 2022-10-07 2024-04-11 Cytiva Us Llc Dissolution system

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JPS5412767Y2 (hu) 1975-08-23 1979-06-02
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DE4393316T1 (de) * 1992-07-13 1995-05-11 Pall Corp Automatisiertes System und Verfahren zur Behandlung eines biologischen Fluids
EP0710148B1 (en) * 1993-07-23 2000-09-13 Kevin Johan Fuchsbichler An apparatus and a method for dissolving a particulate solid in a liquid
AUPO022096A0 (en) * 1996-05-31 1996-06-27 Fuchsbichler, Kevin Johan A mixing or dissolving apparatus
DE29813996U1 (de) 1998-08-05 1998-10-08 Boellhoff Verfahrenstechnik Zw Statikmischer
SE516013C2 (sv) 1998-12-23 2001-11-05 Flaekt Ab Förfarande och anordning vid blandning av en strömmande gas och ett pulverformigt material
SE9903331D0 (sv) * 1999-09-16 1999-09-16 Gambro Lundia Ab Method and apparatus for sterilising a heat sensitive fluid
US7448790B2 (en) * 1999-11-24 2008-11-11 Impulse Devices, Inc. Cavitation fluid circulatory system for a cavitation chamber
US6588929B1 (en) * 2000-09-22 2003-07-08 Kelly N. Dornbush Portable mixing and dispensing apparatus and method
US7449327B2 (en) * 2005-05-03 2008-11-11 Mediatek, Llc System and method for dispensing dehydrated culture media powder
US7810987B2 (en) * 2005-07-27 2010-10-12 Cargill, Incorporated Automated solution maker apparatus
EP2002223A2 (en) * 2006-03-29 2008-12-17 Koninklijke Philips Electronics N.V. Fluid processing and volume determination system
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Also Published As

Publication number Publication date
AU2018292271A1 (en) 2020-01-30
JP7297687B2 (ja) 2023-06-26
CA3068618A1 (en) 2019-01-03
JP2023134437A (ja) 2023-09-27
ES2943648T3 (es) 2023-06-15
CN111094529A (zh) 2020-05-01
KR102628933B1 (ko) 2024-01-24
SG11201913149PA (en) 2020-01-30
US11097237B2 (en) 2021-08-24
EP3645699A1 (en) 2020-05-06
KR20200031627A (ko) 2020-03-24
WO2019005664A1 (en) 2019-01-03
AU2018292271B2 (en) 2024-05-02
US20190001290A1 (en) 2019-01-03
EP3645699B1 (en) 2023-04-12
EP4234071A2 (en) 2023-08-30
DK3645699T3 (da) 2023-07-03
EP4234071A3 (en) 2023-09-27
US11925913B2 (en) 2024-03-12
JP2020526187A (ja) 2020-08-31
US20210362106A1 (en) 2021-11-25

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