HUE061878T2 - A kristályos rozuvasztatin kalcium új polimorf formája és új eljárások a kristályos és amorf rozuvasztatin kalcium elõállítására - Google Patents

A kristályos rozuvasztatin kalcium új polimorf formája és új eljárások a kristályos és amorf rozuvasztatin kalcium elõállítására

Info

Publication number
HUE061878T2
HUE061878T2 HUE16899327A HUE16899327A HUE061878T2 HU E061878 T2 HUE061878 T2 HU E061878T2 HU E16899327 A HUE16899327 A HU E16899327A HU E16899327 A HUE16899327 A HU E16899327A HU E061878 T2 HUE061878 T2 HU E061878T2
Authority
HU
Hungary
Prior art keywords
crystalline
rosuvastatin calcium
well
polymorphic form
novel processes
Prior art date
Application number
HUE16899327A
Other languages
English (en)
Inventor
Sanjay Suri
Pal Madan Tanwar
Kumar Suman Sharma
Kumar Sanjay Mishra
Avinash Aggarwal
Original Assignee
Morepen Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morepen Laboratories Ltd filed Critical Morepen Laboratories Ltd
Publication of HUE061878T2 publication Critical patent/HUE061878T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE16899327A 2016-04-18 2016-06-07 A kristályos rozuvasztatin kalcium új polimorf formája és új eljárások a kristályos és amorf rozuvasztatin kalcium elõállítására HUE061878T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN201613013389 2016-04-18

Publications (1)

Publication Number Publication Date
HUE061878T2 true HUE061878T2 (hu) 2023-08-28

Family

ID=60116610

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16899327A HUE061878T2 (hu) 2016-04-18 2016-06-07 A kristályos rozuvasztatin kalcium új polimorf formája és új eljárások a kristályos és amorf rozuvasztatin kalcium elõállítására

Country Status (5)

Country Link
US (1) US10626093B2 (hu)
EP (1) EP3445751B9 (hu)
HU (1) HUE061878T2 (hu)
PL (1) PL3445751T3 (hu)
WO (1) WO2017183040A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111471034A (zh) * 2020-03-18 2020-07-31 南京欧信医药技术有限公司 连续流微通道反应器中氧化制备瑞舒伐他汀侧链的方法
CN114671859A (zh) * 2022-03-29 2022-06-28 苏州东瑞制药有限公司 一种瑞舒伐他汀钙及其中间体的制备方法
CN115819408A (zh) * 2022-10-21 2023-03-21 宿迁阿尔法科技有限公司 一种高选择性合成瑞舒伐他汀关键中间体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
GB9900339D0 (en) 1999-01-09 1999-02-24 Zeneca Ltd Chemical compounds
KR20040026705A (ko) 2001-08-16 2004-03-31 테바 파마슈티컬 인더스트리즈 리미티드 스타틴의 칼슘 염 형태의 제조 방법
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
WO2005040134A1 (en) * 2003-10-22 2005-05-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous rosuvastatin calcium
US7932387B2 (en) 2005-01-31 2011-04-26 Basf Se Crystalline forms of rosuvastatin calcium salt
WO2011074016A1 (en) * 2009-12-17 2011-06-23 Matrix Laboratories Ltd Novel polymorphic forms of rosuvastatin calcium and process for preparation of the same
WO2012011129A2 (en) 2010-07-22 2012-01-26 Msn Laboratories Limited Novel polymorph of bis[(e)-7-[4-(4-fluorophenyl)-6-iso-propyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid] calcium salt

Also Published As

Publication number Publication date
US10626093B2 (en) 2020-04-21
WO2017183040A1 (en) 2017-10-26
EP3445751A1 (en) 2019-02-27
US20190127334A1 (en) 2019-05-02
EP3445751B9 (en) 2023-07-26
PL3445751T3 (pl) 2023-09-18
EP3445751B1 (en) 2023-04-26
EP3445751A4 (en) 2020-01-22

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