PL3515454T3 - Krystaliczna polimorficzna postać 3-hydroksy-4,5-bis-benzyloksy- 6-benzyloksymetylo-2-fenylo-2-okso-2lambda5-[1,2]oksafosfinanu - Google Patents
Krystaliczna polimorficzna postać 3-hydroksy-4,5-bis-benzyloksy- 6-benzyloksymetylo-2-fenylo-2-okso-2lambda5-[1,2]oksafosfinanuInfo
- Publication number
- PL3515454T3 PL3515454T3 PL17776975T PL17776975T PL3515454T3 PL 3515454 T3 PL3515454 T3 PL 3515454T3 PL 17776975 T PL17776975 T PL 17776975T PL 17776975 T PL17776975 T PL 17776975T PL 3515454 T3 PL3515454 T3 PL 3515454T3
- Authority
- PL
- Poland
- Prior art keywords
- 2lambda5
- oxaphosphinane
- benzyloxymethyl
- benzyloxy
- oxo
- Prior art date
Links
- BFDNKVJGHOSKET-UHFFFAOYSA-N 2-oxo-2-phenyl-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)-1,2$l^{5}-oxaphosphinan-3-ol Chemical compound C=1C=CC=CC=1COC1C(COCC=2C=CC=CC=2)OP(C=2C=CC=CC=2)(=O)C(O)C1OCC1=CC=CC=C1 BFDNKVJGHOSKET-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657172—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and one oxygen atom being part of a (thio)phosphinic acid ester: (X = O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16306202.9A EP3295944A1 (en) | 2016-09-20 | 2016-09-20 | Crystalline polymorphic form of 3-hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl-2-oxo-2lambda5-[1,2]oxaphosphinane |
EP17776975.9A EP3515454B1 (en) | 2016-09-20 | 2017-09-19 | Crystalline polymorphic form of 3-hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl-2-oxo-2lambda5-[1,2]oxaphosphinane |
PCT/EP2017/073682 WO2018054925A1 (en) | 2016-09-20 | 2017-09-19 | Crystalline polymorphic form of 3-hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl-2-oxo-2lambda5-[1,2]oxaphosphinane |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3515454T3 true PL3515454T3 (pl) | 2021-05-31 |
Family
ID=57130310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL17776975T PL3515454T3 (pl) | 2016-09-20 | 2017-09-19 | Krystaliczna polimorficzna postać 3-hydroksy-4,5-bis-benzyloksy- 6-benzyloksymetylo-2-fenylo-2-okso-2lambda5-[1,2]oksafosfinanu |
Country Status (12)
Country | Link |
---|---|
US (1) | US10597414B2 (pl) |
EP (2) | EP3295944A1 (pl) |
JP (2) | JP7235661B2 (pl) |
KR (1) | KR102566383B1 (pl) |
CN (1) | CN109843300B (pl) |
AU (1) | AU2017329753B2 (pl) |
CA (1) | CA3037093A1 (pl) |
DK (1) | DK3515454T3 (pl) |
ES (1) | ES2844425T3 (pl) |
PL (1) | PL3515454T3 (pl) |
PT (1) | PT3515454T (pl) |
WO (1) | WO2018054925A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202237093A (zh) | 2021-01-13 | 2022-10-01 | 法商弗斯汀治療公司 | 治療纖維化疾病的方法 |
TW202404609A (zh) * | 2022-05-20 | 2024-02-01 | 法商弗斯汀治療公司 | 雜環次膦酸化合物之劑量及投藥方案 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2170912B3 (en) * | 2007-07-05 | 2022-06-15 | Centre National De La Recherche Scientifique | New phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same |
FR3002451B1 (fr) | 2013-02-25 | 2015-06-26 | Centre Nat Rech Scient | Heterocycles phosphores analogues de sucres a activite antimetastatique |
-
2016
- 2016-09-20 EP EP16306202.9A patent/EP3295944A1/en not_active Withdrawn
-
2017
- 2017-09-19 JP JP2019536688A patent/JP7235661B2/ja active Active
- 2017-09-19 CN CN201780057865.3A patent/CN109843300B/zh active Active
- 2017-09-19 CA CA3037093A patent/CA3037093A1/en active Pending
- 2017-09-19 AU AU2017329753A patent/AU2017329753B2/en active Active
- 2017-09-19 EP EP17776975.9A patent/EP3515454B1/en active Active
- 2017-09-19 PL PL17776975T patent/PL3515454T3/pl unknown
- 2017-09-19 US US16/332,983 patent/US10597414B2/en active Active
- 2017-09-19 ES ES17776975T patent/ES2844425T3/es active Active
- 2017-09-19 PT PT177769759T patent/PT3515454T/pt unknown
- 2017-09-19 KR KR1020197010181A patent/KR102566383B1/ko active IP Right Grant
- 2017-09-19 WO PCT/EP2017/073682 patent/WO2018054925A1/en unknown
- 2017-09-19 DK DK17776975.9T patent/DK3515454T3/da active
-
2022
- 2022-07-07 JP JP2022109723A patent/JP2022125284A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP3515454B1 (en) | 2020-11-11 |
EP3295944A1 (en) | 2018-03-21 |
US10597414B2 (en) | 2020-03-24 |
ES2844425T3 (es) | 2021-07-22 |
KR102566383B1 (ko) | 2023-08-11 |
CN109843300A (zh) | 2019-06-04 |
US20190330252A1 (en) | 2019-10-31 |
CN109843300B (zh) | 2021-08-27 |
PT3515454T (pt) | 2021-01-18 |
AU2017329753A1 (en) | 2019-04-04 |
JP2022125284A (ja) | 2022-08-26 |
JP2019529552A (ja) | 2019-10-17 |
KR20190058518A (ko) | 2019-05-29 |
EP3515454A1 (en) | 2019-07-31 |
CA3037093A1 (en) | 2018-03-29 |
WO2018054925A1 (en) | 2018-03-29 |
JP7235661B2 (ja) | 2023-03-08 |
AU2017329753B2 (en) | 2022-05-19 |
DK3515454T3 (da) | 2021-01-18 |
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