HUE054225T2 - Módszerek a daganatból származó DNA CPG-metilációjának kimutatására vérmintákban - Google Patents

Módszerek a daganatból származó DNA CPG-metilációjának kimutatására vérmintákban

Info

Publication number
HUE054225T2
HUE054225T2 HUE17702586A HUE17702586A HUE054225T2 HU E054225 T2 HUE054225 T2 HU E054225T2 HU E17702586 A HUE17702586 A HU E17702586A HU E17702586 A HUE17702586 A HU E17702586A HU E054225 T2 HUE054225 T2 HU E054225T2
Authority
HU
Hungary
Prior art keywords
tumor
methods
blood samples
derived dna
cpg methylation
Prior art date
Application number
HUE17702586A
Other languages
English (en)
Inventor
Joern Lewin
Denise Kottwitz
Selina Esche
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of HUE054225T2 publication Critical patent/HUE054225T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HUE17702586A 2016-01-29 2017-01-27 Módszerek a daganatból származó DNA CPG-metilációjának kimutatására vérmintákban HUE054225T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16153452 2016-01-29

Publications (1)

Publication Number Publication Date
HUE054225T2 true HUE054225T2 (hu) 2021-08-30

Family

ID=55272352

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17702586A HUE054225T2 (hu) 2016-01-29 2017-01-27 Módszerek a daganatból származó DNA CPG-metilációjának kimutatására vérmintákban

Country Status (11)

Country Link
US (1) US20190032148A1 (hu)
EP (2) EP3828281A1 (hu)
JP (2) JP7261587B2 (hu)
CN (1) CN109312404A (hu)
DK (1) DK3408407T3 (hu)
ES (1) ES2849559T3 (hu)
HR (1) HRP20210198T1 (hu)
HU (1) HUE054225T2 (hu)
LT (1) LT3408407T (hu)
SI (1) SI3408407T1 (hu)
WO (1) WO2017129716A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3368686A1 (en) 2015-10-30 2018-09-05 Exact Sciences Development Company, LLC Multiplex amplification detection assay and isolation and detection of dna from plasma
CN116064796A (zh) 2016-05-05 2023-05-05 精密科学公司 通过分析甲基化dna来检测肺肿瘤
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
AU2018211956A1 (en) * 2017-01-27 2019-07-25 Exact Sciences Corporation Detection of colon neoplasia by analysis of methylated DNA
WO2019178496A1 (en) * 2018-03-15 2019-09-19 Grail, Inc. Tissue-specific methylation marker
CN116064815A (zh) * 2019-02-14 2023-05-05 博尔诚(北京)科技有限公司 一种食管癌、胃癌、肠癌、肝癌和/或胰腺癌患癌、癌前筛查组合物及其用途
WO2021192397A1 (ja) * 2020-03-25 2021-09-30 富士フイルム株式会社 がん検査方法
CN111540469A (zh) * 2020-05-29 2020-08-14 杭州广科安德生物科技有限公司 构建体外检测胃癌的数学模型的方法及其应用
CN112375822B (zh) * 2020-06-01 2021-11-02 广州市基准医疗有限责任公司 用于检测乳腺癌的甲基化生物标记物及其应用
EP4278006A1 (en) * 2021-01-12 2023-11-22 The Board of Trustees of the Leland Stanford Junior University Layered analysis of methylated biomarkers for use in cancer diagnosis and prognosis
WO2023017001A1 (en) 2021-08-09 2023-02-16 Epigenomics Ag Improved methods for detecting colorectal cancer
WO2024074558A1 (en) 2022-10-04 2024-04-11 Epigenomics Ag Improved methods for detecting cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2877000A (en) * 1999-02-10 2000-08-29 University Of Maryland Photo-induced nucleic acid hybridization
JP2004516821A (ja) * 2000-09-01 2004-06-10 エピゲノミクス アーゲー ゲノムDNA上の、配列コンテクスト5−CpG−3内の特定シトシンのメチル化度の定量方法
EP1394172A1 (en) 2002-08-29 2004-03-03 Boehringer Mannheim Gmbh Improved method for bisulfite treatment
GB201000688D0 (en) 2010-01-15 2010-03-03 Diagenic Asa Product and method
AU2013266341B2 (en) * 2012-05-22 2019-01-03 The Johns Hopkins University A quantitative multiplex methylation specific PCR method- cMethDNA, reagents, and its use
WO2014036314A2 (en) * 2012-08-31 2014-03-06 Ignyta, Inc. Diagnosis of rheumatoid arthritis (ra) using differentially methylated loci identified in peripheral blood mononuclear cells, t-cells, b-cells and monocytes
IL280521B (en) * 2014-06-04 2022-07-01 Quest Diagnostics Invest Inc Suspended markers for colon and rectal cancer

Also Published As

Publication number Publication date
HRP20210198T1 (hr) 2021-04-16
EP3408407B1 (en) 2021-01-06
SI3408407T1 (sl) 2021-04-30
LT3408407T (lt) 2021-03-10
JP7261587B2 (ja) 2023-04-20
CN109312404A (zh) 2019-02-05
EP3408407A1 (en) 2018-12-05
JP2023052157A (ja) 2023-04-11
JP2019504642A (ja) 2019-02-21
EP3828281A1 (en) 2021-06-02
ES2849559T3 (es) 2021-08-19
DK3408407T3 (da) 2021-02-08
US20190032148A1 (en) 2019-01-31
WO2017129716A1 (en) 2017-08-03

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