HUE053184T2 - Eljárás 6-(5-etoxihept-1-il)biciklo[3.3.0]oktán-3-on elõállítására - Google Patents

Eljárás 6-(5-etoxihept-1-il)biciklo[3.3.0]oktán-3-on elõállítására

Info

Publication number
HUE053184T2
HUE053184T2 HUE13877627A HUE13877627A HUE053184T2 HU E053184 T2 HUE053184 T2 HU E053184T2 HU E13877627 A HUE13877627 A HU E13877627A HU E13877627 A HUE13877627 A HU E13877627A HU E053184 T2 HUE053184 T2 HU E053184T2
Authority
HU
Hungary
Prior art keywords
ethoxyhept
octan
bicyclo
synthesizing
Prior art date
Application number
HUE13877627A
Other languages
English (en)
Inventor
Witenburg Jimmy Van
Crois Rene La
Original Assignee
Grey Pacific Labs Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grey Pacific Labs Llc filed Critical Grey Pacific Labs Llc
Publication of HUE053184T2 publication Critical patent/HUE053184T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/34Separation; Purification; Stabilisation; Use of additives
    • C07C41/46Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/162Unsaturated ethers containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/76Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton with the aid of ketenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/86Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/517Saturated compounds containing a keto group being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/613Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C07C49/623Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings
    • C07C49/633Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings the condensed ring system containing eight or nine carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/20All rings being cycloaliphatic the ring system containing seven carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/22All rings being cycloaliphatic the ring system containing eight carbon atoms, e.g. pentalene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HUE13877627A 2013-03-11 2013-03-11 Eljárás 6-(5-etoxihept-1-il)biciklo[3.3.0]oktán-3-on elõállítására HUE053184T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2013/000360 WO2014140655A1 (en) 2013-03-11 2013-03-11 Method of synthesis
EP13877627.3A EP2970071B1 (en) 2013-03-11 2013-03-11 Method of synthesizing 6-(5-ethoxyhept-1-yl)bicyclo[3.3.0]octan-3-one

Publications (1)

Publication Number Publication Date
HUE053184T2 true HUE053184T2 (hu) 2021-06-28

Family

ID=51535921

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13877627A HUE053184T2 (hu) 2013-03-11 2013-03-11 Eljárás 6-(5-etoxihept-1-il)biciklo[3.3.0]oktán-3-on elõállítására

Country Status (18)

Country Link
US (3) US20160016874A1 (hu)
EP (2) EP2970071B1 (hu)
JP (1) JP6335936B2 (hu)
KR (2) KR20180050764A (hu)
CN (2) CN107266303B (hu)
AU (1) AU2013382072B2 (hu)
BR (1) BR112015021973B1 (hu)
CA (1) CA2904558C (hu)
ES (1) ES2853929T3 (hu)
HK (1) HK1216419A1 (hu)
HU (1) HUE053184T2 (hu)
IL (1) IL241475A0 (hu)
MX (1) MX2015012020A (hu)
NZ (1) NZ711989A (hu)
PH (1) PH12015502008A1 (hu)
RU (1) RU2634698C2 (hu)
SG (1) SG11201507157YA (hu)
WO (1) WO2014140655A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015021973B1 (pt) 2013-03-11 2022-08-16 Grey Pacific Labs, Llc Método de síntese

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689345A (en) 1982-05-06 1987-08-25 Cbd Corporation Oxygenated alkyl substituted bicyclo alkanes
WO1983004019A1 (en) * 1982-05-06 1983-11-24 Cbd Corporation Cycloaliphatic pharmaceutical compounds
US4689349A (en) 1982-05-06 1987-08-25 Cbd Corporation Anti-tumor halo bicyclo alkanones
ZA848741B (en) * 1983-11-08 1985-07-31 Walter J Kasha Pharmaceutical composition for inhibition of tumours
US4731458A (en) * 1986-04-25 1988-03-15 Cbd Corporation Spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] derivatives
CN1062898A (zh) * 1991-12-30 1992-07-22 中国科招高技术有限公司 2-(5-甲氧基-1-庚基)双环(3,3,o)辛烷-7-酮的合成方法
DE4204808A1 (de) * 1992-02-18 1993-08-19 Basf Ag Verfahren zur herstellung von (omega)-formylalkancarbonsaeureestern
US5264619B1 (en) * 1993-01-15 1996-05-14 Cosmos Pharm Corp Anti-androgenic cyclo and bicyclo alkenes
AU2001100223A4 (en) 2001-08-01 2001-09-20 Peter Michael Murphy Parallel drive differential
KR20160052812A (ko) * 2008-04-14 2016-05-12 할로자임, 아이엔씨 히알루로난 관련 질환 및 상태 치료용 변형된 히알루로니다제 및 그 용도
US8410314B1 (en) * 2010-06-21 2013-04-02 Bcs Business Consulting Services Pte Ltd. Method of synthesis
CN102311440B (zh) * 2010-07-02 2015-01-07 无锡药明康德生物技术有限公司 1-甲氧羰基-3-苄基-8-叔丁氧羰基-3,8-二氮杂双环[3.2.1]辛烷及制备方法
AU2011200223A1 (en) * 2011-01-20 2012-08-09 Norman Graham Haines An Attachment for Mounting Wear Parts
NZ591253A (en) * 2011-02-18 2011-07-29 Bcs Business Consulting Services Pte Ltd Process for producing 6-(5-ethoxy-hept-1-yl)bicyclo[3.3.0]octane-3-one and product thereof
BR112015021973B1 (pt) 2013-03-11 2022-08-16 Grey Pacific Labs, Llc Método de síntese

Also Published As

Publication number Publication date
EP2970071A4 (en) 2016-11-02
PH12015502008B1 (en) 2016-01-11
JP2016515112A (ja) 2016-05-26
US20170204040A1 (en) 2017-07-20
US20190194107A1 (en) 2019-06-27
SG11201507157YA (en) 2015-10-29
AU2013382072B2 (en) 2017-08-31
HK1216419A1 (zh) 2016-11-11
WO2014140655A1 (en) 2014-09-18
EP3838881C0 (en) 2024-02-14
EP2970071A1 (en) 2016-01-20
KR20150135338A (ko) 2015-12-02
RU2015138272A (ru) 2017-04-18
RU2634698C2 (ru) 2017-11-03
PH12015502008A1 (en) 2016-01-11
AU2013382072A1 (en) 2015-10-22
US20160016874A1 (en) 2016-01-21
CN105143162A (zh) 2015-12-09
JP6335936B2 (ja) 2018-05-30
IL241475A0 (en) 2015-11-30
CA2904558A1 (en) 2014-09-18
US10150724B2 (en) 2018-12-11
ES2853929T3 (es) 2021-09-20
NZ711989A (en) 2017-08-25
EP3838881A1 (en) 2021-06-23
EP3838881B1 (en) 2024-02-14
KR20180050764A (ko) 2018-05-15
EP2970071B1 (en) 2020-11-18
MX2015012020A (es) 2016-04-06
CN107266303A (zh) 2017-10-20
CN105143162B (zh) 2017-04-26
BR112015021973A2 (hu) 2017-08-22
CA2904558C (en) 2018-12-04
BR112015021973B1 (pt) 2022-08-16
CN107266303B (zh) 2021-04-13

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