HUE050811T2 - Avelumab anti-PD-1 ellenanyagot tartalmazó vizes gyógyászati kiszerelés - Google Patents
Avelumab anti-PD-1 ellenanyagot tartalmazó vizes gyógyászati kiszerelésInfo
- Publication number
- HUE050811T2 HUE050811T2 HUE16818985A HUE16818985A HUE050811T2 HU E050811 T2 HUE050811 T2 HU E050811T2 HU E16818985 A HUE16818985 A HU E16818985A HU E16818985 A HUE16818985 A HU E16818985A HU E050811 T2 HUE050811 T2 HU E050811T2
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical formulation
- aqueous pharmaceutical
- antibody avelumab
- avelumab
- antibody
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15198233 | 2015-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE050811T2 true HUE050811T2 (hu) | 2021-01-28 |
Family
ID=54838201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16818985A HUE050811T2 (hu) | 2015-12-07 | 2016-12-05 | Avelumab anti-PD-1 ellenanyagot tartalmazó vizes gyógyászati kiszerelés |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US11058769B2 (hu) |
| EP (2) | EP3747466A1 (hu) |
| JP (1) | JP6925337B2 (hu) |
| KR (1) | KR20180085801A (hu) |
| CN (1) | CN108367072B (hu) |
| AR (1) | AR107014A1 (hu) |
| AU (1) | AU2016368099C1 (hu) |
| BR (1) | BR112018010211A2 (hu) |
| CA (1) | CA3007481C (hu) |
| CL (1) | CL2018001488A1 (hu) |
| CO (1) | CO2018005525A2 (hu) |
| CY (1) | CY1123358T1 (hu) |
| DK (1) | DK3386541T3 (hu) |
| EA (1) | EA201891339A1 (hu) |
| ES (1) | ES2823279T3 (hu) |
| HK (1) | HK1257781A1 (hu) |
| HR (1) | HRP20201573T1 (hu) |
| HU (1) | HUE050811T2 (hu) |
| IL (1) | IL259563B (hu) |
| LT (1) | LT3386541T (hu) |
| MX (1) | MX2018006875A (hu) |
| MY (1) | MY195681A (hu) |
| NZ (1) | NZ743964A (hu) |
| PE (1) | PE20181400A1 (hu) |
| PH (1) | PH12018500894A1 (hu) |
| PL (1) | PL3386541T3 (hu) |
| PT (1) | PT3386541T (hu) |
| RS (1) | RS61029B1 (hu) |
| SA (1) | SA518391743B1 (hu) |
| SG (1) | SG11201804758QA (hu) |
| SI (1) | SI3386541T1 (hu) |
| TW (1) | TWI630917B (hu) |
| UA (1) | UA123270C2 (hu) |
| WO (1) | WO2017097407A1 (hu) |
| ZA (1) | ZA201804534B (hu) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012344260B2 (en) * | 2011-11-28 | 2017-09-07 | Merck Patent Gmbh | Anti-PD-L1 antibodies and uses thereof |
| EP3049442A4 (en) | 2013-09-26 | 2017-06-28 | Costim Pharmaceuticals Inc. | Methods for treating hematologic cancers |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| WO2016040880A1 (en) | 2014-09-13 | 2016-03-17 | Novartis Ag | Combination therapies of alk inhibitors |
| AU2015333687B2 (en) | 2014-10-14 | 2021-03-18 | Dana-Farber Cancer Institute, Inc. | Antibody molecules to PD-L1 and uses thereof |
| MA42971A (fr) | 2015-03-13 | 2018-08-15 | Cytomx Therapeutics Inc | Anticorps anti-pdl1, anticorps anti-pld1 activables, et leurs procédés d'utilisation |
| JP6925337B2 (ja) | 2015-12-07 | 2021-08-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 抗ｐｄ−ｌ１抗体アベルマブを含む水性医薬製剤 |
| CA3027209C (en) | 2016-06-13 | 2022-08-16 | I-Mab | Anti-pd-l1 antibodies and uses thereof |
| BR112019006504A2 (pt) | 2016-10-06 | 2019-06-25 | Merck Patent Gmbh | regime de dosagem de avelumabe para o tratamento de câncer |
| KR20190125363A (ko) * | 2017-03-06 | 2019-11-06 | 메르크 파텐트 게엠베하 | 수성 항-pd-l1 항체 제제 |
| BR112019025188A2 (pt) | 2017-06-01 | 2020-06-23 | Cytomx Therapeutics, Inc. | Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos |
| CN111246886B (zh) * | 2017-11-02 | 2022-03-15 | 正大天晴药业集团股份有限公司 | 一种抗pd-l1人源化单克隆抗体的药物组合物 |
| WO2020020307A1 (en) | 2018-07-25 | 2020-01-30 | I-Mab Biopharma Co., Ltd. | Anti-cd73 anti-pd-l1 bispecific antibodies |
| WO2020060183A1 (ko) * | 2018-09-18 | 2020-03-26 | 삼성바이오에피스 주식회사 | 트라스투주맙 항체 안정화 액체 제제 |
| JP2022513693A (ja) * | 2018-11-29 | 2022-02-09 | ハーバー・バイオメド・セラピューティクス・リミテッド | 抗ｐｄ－ｌ１抗体製剤 |
| BR112021015034A2 (pt) | 2019-02-18 | 2021-10-05 | Eli Lilly And Company | Formulação de anticorpo terapêutico |
| JP2022540781A (ja) * | 2019-06-25 | 2022-09-20 | イノベント バイオロジクス（スーチョウ）カンパニー，リミティド | 抗ｃｄ４７／ｐｄ‐ｌ１二重特異性抗体を含む製剤、その調製方法及び使用 |
| TW202114637A (zh) * | 2019-08-22 | 2021-04-16 | 俄羅斯聯邦商拜奧卡德聯合股份公司 | 抗ｐｄ－１抗體ｐｒｏｌｇｏｌｉｍａｂ的水性藥物組合物及其用途 |
| AU2020402369A1 (en) * | 2019-12-13 | 2022-07-14 | Samsung Bioepis Co., Ltd. | Stable anti-PD-1 antibody pharmaceutical preparation |
| AU2022302143A1 (en) | 2021-07-02 | 2024-01-18 | Venugopalareddy BOMMIREDDYVENKATA | Compositions and methods for treating cancers |
| AU2022340804A1 (en) | 2021-08-31 | 2024-03-21 | Gennao Bio, Inc. | Compositions and methods for treating cancers |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP5209476B2 (ja) | 2005-09-02 | 2013-06-12 | グリコミメティクス， インコーポレイテッド | ヘテロ二官能性全セレクチン阻害剤 |
| BRPI0622256A2 (pt) | 2005-12-20 | 2011-08-09 | Bristol-Myers Squibb Company | formulações estáveis adequadas para administração subcutánea compreendendo moléculas de ctla4ig |
| US8895510B2 (en) | 2008-04-08 | 2014-11-25 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
| PE20120341A1 (es) * | 2008-12-09 | 2012-04-24 | Genentech Inc | Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t |
| EP2196476A1 (en) * | 2008-12-10 | 2010-06-16 | Novartis Ag | Antibody formulation |
| CN102686241A (zh) * | 2009-12-29 | 2012-09-19 | 霍夫曼-拉罗奇有限公司 | 抗体配制剂 |
| WO2012037034A1 (en) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | E-selectin antagonists |
| EP2691112B1 (en) * | 2011-03-31 | 2018-05-23 | Merck Sharp & Dohme Corp. | Stable formulations of antibodies to human programmed death receptor pd-1 and related treatments |
| AU2012344260B2 (en) * | 2011-11-28 | 2017-09-07 | Merck Patent Gmbh | Anti-PD-L1 antibodies and uses thereof |
| NZ627859A (en) * | 2012-01-23 | 2015-09-25 | Regeneron Pharma | Stabilized formulations containing anti-ang2 antibodies |
| US9216219B2 (en) * | 2012-06-12 | 2015-12-22 | Novartis Ag | Anti-BAFFR antibody formulation |
| SG10201708542RA (en) * | 2013-09-27 | 2017-12-28 | Genentech Inc | Anti-pdl1 antibody formulations |
| US10376582B2 (en) * | 2013-10-16 | 2019-08-13 | Outlook Therapeutics, Inc. | Buffer formulations for enhanced antibody stability |
| CN115590953A (zh) * | 2014-05-15 | 2023-01-13 | 百时美施贵宝公司（Us） | 使用抗pd-1抗体和另一种抗癌剂的组合治疗肺癌 |
| CN105085680A (zh) * | 2014-05-23 | 2015-11-25 | 复旦大学 | 人源化抗PD-1及c-MET双特异性抗体及其制备方法和应用 |
| JP6885869B2 (ja) | 2015-02-26 | 2021-06-16 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | がんを治療するためのｐｄ−１／ｐｄ−ｌ１阻害剤 |
| CA2929848A1 (en) | 2015-05-14 | 2016-11-14 | Pfizer Inc. | Combination therapies comprising a pyrrolidine-2,5-dione ido1 inhibitor and an anti-pd1/anti-pd-l1 antibody |
| WO2016200835A1 (en) | 2015-06-08 | 2016-12-15 | Genentech, Inc. | Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists |
| AU2016280003B2 (en) | 2015-06-16 | 2021-09-16 | Merck Patent Gmbh | PD-L1 antagonist combination treatments |
| JP2018529719A (ja) | 2015-09-30 | 2018-10-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ａｌｋ陰性がんを処置するためのｐｄ−１系結合アンタゴニストおよびａｌｋ阻害剤の組合せ |
| JP6925337B2 (ja) | 2015-12-07 | 2021-08-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 抗ｐｄ−ｌ１抗体アベルマブを含む水性医薬製剤 |
| KR20190125363A (ko) | 2017-03-06 | 2019-11-06 | 메르크 파텐트 게엠베하 | 수성 항-pd-l1 항체 제제 |
-
2016
- 2016-12-05 JP JP2018529213A patent/JP6925337B2/ja active Active
- 2016-12-05 EP EP20184113.7A patent/EP3747466A1/en not_active Withdrawn
- 2016-12-05 UA UAA201807363A patent/UA123270C2/uk unknown
- 2016-12-05 CA CA3007481A patent/CA3007481C/en active Active
- 2016-12-05 RS RS20201201A patent/RS61029B1/sr unknown
- 2016-12-05 MX MX2018006875A patent/MX2018006875A/es unknown
- 2016-12-05 US US16/060,319 patent/US11058769B2/en active Active
- 2016-12-05 LT LTEP16818985.0T patent/LT3386541T/lt unknown
- 2016-12-05 NZ NZ743964A patent/NZ743964A/en unknown
- 2016-12-05 PT PT168189850T patent/PT3386541T/pt unknown
- 2016-12-05 KR KR1020187019480A patent/KR20180085801A/ko active Search and Examination
- 2016-12-05 MY MYPI2018702171A patent/MY195681A/en unknown
- 2016-12-05 ES ES16818985T patent/ES2823279T3/es active Active
- 2016-12-05 HU HUE16818985A patent/HUE050811T2/hu unknown
- 2016-12-05 BR BR112018010211A patent/BR112018010211A2/pt active Search and Examination
- 2016-12-05 CN CN201680071740.1A patent/CN108367072B/zh active Active
- 2016-12-05 WO PCT/EP2016/002040 patent/WO2017097407A1/en active Application Filing
- 2016-12-05 SG SG11201804758QA patent/SG11201804758QA/en unknown
- 2016-12-05 AU AU2016368099A patent/AU2016368099C1/en active Active
- 2016-12-05 SI SI201630940T patent/SI3386541T1/sl unknown
- 2016-12-05 PE PE2018001077A patent/PE20181400A1/es unknown
- 2016-12-05 DK DK16818985.0T patent/DK3386541T3/da active
- 2016-12-05 EA EA201891339A patent/EA201891339A1/ru unknown
- 2016-12-05 EP EP16818985.0A patent/EP3386541B1/en active Active
- 2016-12-05 PL PL16818985T patent/PL3386541T3/pl unknown
- 2016-12-06 TW TW105140288A patent/TWI630917B/zh active
- 2016-12-07 AR ARP160103760A patent/AR107014A1/es unknown
-
2018
- 2018-04-26 PH PH12018500894A patent/PH12018500894A1/en unknown
- 2018-05-23 IL IL259563A patent/IL259563B/en active IP Right Grant
- 2018-05-25 CO CONC2018/0005525A patent/CO2018005525A2/es unknown
- 2018-06-04 CL CL2018001488A patent/CL2018001488A1/es unknown
- 2018-06-06 SA SA518391743A patent/SA518391743B1/ar unknown
- 2018-07-06 ZA ZA201804534A patent/ZA201804534B/en unknown
-
2019
- 2019-01-04 HK HK19100169.4A patent/HK1257781A1/zh unknown
-
2020
- 2020-09-24 CY CY20201100904T patent/CY1123358T1/el unknown
- 2020-10-05 HR HRP20201573TT patent/HRP20201573T1/hr unknown
- 2020-12-09 US US17/116,587 patent/US20210100903A1/en not_active Abandoned
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