HUE043374T2 - Vegyület, amelynek van szomatosztatin receptor agonista aktivitása és annak gyógyszerészeti felhasználása - Google Patents
Vegyület, amelynek van szomatosztatin receptor agonista aktivitása és annak gyógyszerészeti felhasználásaInfo
- Publication number
- HUE043374T2 HUE043374T2 HUE14847684A HUE14847684A HUE043374T2 HU E043374 T2 HUE043374 T2 HU E043374T2 HU E14847684 A HUE14847684 A HU E14847684A HU E14847684 A HUE14847684 A HU E14847684A HU E043374 T2 HUE043374 T2 HU E043374T2
- Authority
- HU
- Hungary
- Prior art keywords
- compound
- pharmaceutical use
- somatostatin receptor
- agonistic activity
- receptor agonistic
- Prior art date
Links
- 108050001286 Somatostatin Receptor Proteins 0.000 title 1
- 102000011096 Somatostatin receptor Human genes 0.000 title 1
- 230000001270 agonistic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013205027 | 2013-09-30 | ||
JP2013268902 | 2013-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE043374T2 true HUE043374T2 (hu) | 2019-08-28 |
Family
ID=52743606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14847684A HUE043374T2 (hu) | 2013-09-30 | 2014-09-29 | Vegyület, amelynek van szomatosztatin receptor agonista aktivitása és annak gyógyszerészeti felhasználása |
Country Status (21)
Country | Link |
---|---|
US (1) | US9643951B2 (hu) |
EP (1) | EP3053916B1 (hu) |
JP (1) | JP6380402B2 (hu) |
KR (1) | KR20160062023A (hu) |
CN (1) | CN105593221B (hu) |
AU (1) | AU2014325078B2 (hu) |
BR (1) | BR112016007078A2 (hu) |
CA (1) | CA2925651A1 (hu) |
DK (1) | DK3053916T3 (hu) |
ES (1) | ES2716151T3 (hu) |
HK (1) | HK1223356A1 (hu) |
HU (1) | HUE043374T2 (hu) |
IL (1) | IL244813A0 (hu) |
MX (1) | MX2016004088A (hu) |
PH (1) | PH12016500573A1 (hu) |
PL (1) | PL3053916T3 (hu) |
PT (1) | PT3053916T (hu) |
RU (1) | RU2666352C2 (hu) |
SG (1) | SG11201602477YA (hu) |
TW (1) | TWI628175B (hu) |
WO (1) | WO2015046482A1 (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210134838A (ko) * | 2016-07-14 | 2021-11-10 | 크리네틱스 파마슈티칼스, 인크. | 소마토스타틴 조절제 및 그의 용도 |
US20200000816A1 (en) * | 2017-02-08 | 2020-01-02 | Ono Pharmaceutical Co., Ltd. | Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof |
BR112019019168A2 (pt) | 2017-03-16 | 2020-04-14 | Crinetics Pharmaceuticals Inc | moduladores de somatostatina e usos dos mesmos |
US11028068B2 (en) | 2017-07-25 | 2021-06-08 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
KR102462586B1 (ko) * | 2018-01-17 | 2022-11-03 | 크리네틱스 파마슈티칼스, 인크. | 소마토스타틴 조절제의 제조 방법 |
WO2019157458A1 (en) * | 2018-02-12 | 2019-08-15 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
WO2019240246A1 (ja) * | 2018-06-15 | 2019-12-19 | 小野薬品工業株式会社 | ピペリジノール誘導体の新規な塩および新規結晶形 |
JP7431813B2 (ja) | 2018-09-18 | 2024-02-15 | クリネティックス ファーマシューティカルズ,インク. | ソマトスタチンモジュレーターとその使用 |
WO2021030262A1 (en) * | 2019-08-14 | 2021-02-18 | Crinetics Pharmaceuticals, Inc. | Nonpeptide somatostatin type 5 receptor agonists and uses thereof |
EP4210700A1 (en) | 2020-09-09 | 2023-07-19 | Crinetics Pharmaceuticals, Inc. | Formulations of a somatostatin modulator |
MX2023009603A (es) | 2021-02-17 | 2023-08-24 | Crinetics Pharmaceuticals Inc | Formas cristalinas de un modulador de somatostatina. |
CN116789674B (zh) * | 2022-08-24 | 2024-05-24 | 杭州高光制药有限公司 | Nlrp3炎性小体抑制剂 |
WO2024089668A1 (en) * | 2022-10-28 | 2024-05-02 | Basecamp Bio Inc. | Somatostatin receptor 2 agonists and uses thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0862562B1 (en) | 1995-09-13 | 2001-07-04 | Takeda Chemical Industries, Ltd. | Benzoxazepine compounds, their production and use as lipid lowering agents |
US6057338A (en) * | 1997-04-04 | 2000-05-02 | Merck & Co., Inc. | Somatostatin agonists |
US6025372A (en) | 1997-04-04 | 2000-02-15 | Merck & Co., Inc. | Somatostatin agonists |
AU1285499A (en) * | 1997-10-30 | 1999-05-24 | Merck & Co., Inc. | Somatostatin agonists |
AR029876A1 (es) | 1998-05-11 | 2003-07-23 | Takeda Pharmaceutical | Compuesto de acido oxiiminoalcanoilo, composicion farmaceutica y agente para controlar receptores relacionados con retinoide que lo comprenden y su uso |
AR035016A1 (es) | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
WO2001025228A1 (fr) | 1999-10-07 | 2001-04-12 | Tadeka Chemical Industries, Ltd. | Derives d'amines |
SK6432002A3 (en) | 1999-11-10 | 2003-02-04 | Takeda Chemical Industries Ltd | 5-Membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity |
FR2802206B1 (fr) | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
DE60142961D1 (de) | 2000-04-28 | 2010-10-14 | Takeda Pharmaceutical | Antagonisten des melanin-konzentrierenden hormons |
CA2408913A1 (en) | 2000-05-16 | 2001-11-22 | Takeda Chemical Industries, Ltd. | Melanin-concentrating hormone antagonist |
US20050245571A1 (en) | 2001-10-19 | 2005-11-03 | Hidenori Abe | Amine derivative |
AR044852A1 (es) * | 2003-06-24 | 2005-10-05 | Novartis Ag | Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina |
US20090196912A1 (en) | 2004-07-30 | 2009-08-06 | Gpc Botech Ag | Pyridinylamines |
CN101258152A (zh) | 2005-07-04 | 2008-09-03 | 阿斯利康(瑞典)有限公司 | 作为pde4抑制剂用于治疗炎症和免疫疾病的吡啶并嘧啶衍生物 |
TW200726767A (en) | 2005-07-04 | 2007-07-16 | Astrazeneca Ab | Chemical compounds 2 |
AU2007309708A1 (en) * | 2006-03-13 | 2008-05-02 | Merck Sharp & Dohme Corp. | Somatostatin agonists |
JP2010500391A (ja) | 2006-08-15 | 2010-01-07 | エフ.ホフマン−ラ ロシュ アーゲー | フェニル、ピリジン及びキノリン誘導体 |
GB0818241D0 (en) * | 2008-10-06 | 2008-11-12 | Cancer Res Technology | Compounds and their use |
WO2014007228A1 (ja) | 2012-07-03 | 2014-01-09 | 小野薬品工業株式会社 | ソマトスタチン受容体作動活性を有する化合物およびその医薬用途 |
-
2014
- 2014-09-29 PL PL14847684T patent/PL3053916T3/pl unknown
- 2014-09-29 ES ES14847684T patent/ES2716151T3/es active Active
- 2014-09-29 MX MX2016004088A patent/MX2016004088A/es unknown
- 2014-09-29 KR KR1020167008316A patent/KR20160062023A/ko not_active Application Discontinuation
- 2014-09-29 JP JP2015539407A patent/JP6380402B2/ja not_active Expired - Fee Related
- 2014-09-29 US US15/025,739 patent/US9643951B2/en active Active
- 2014-09-29 TW TW103133704A patent/TWI628175B/zh not_active IP Right Cessation
- 2014-09-29 WO PCT/JP2014/075794 patent/WO2015046482A1/ja active Application Filing
- 2014-09-29 AU AU2014325078A patent/AU2014325078B2/en not_active Ceased
- 2014-09-29 DK DK14847684.9T patent/DK3053916T3/en active
- 2014-09-29 PT PT14847684T patent/PT3053916T/pt unknown
- 2014-09-29 CN CN201480053967.4A patent/CN105593221B/zh not_active Expired - Fee Related
- 2014-09-29 HU HUE14847684A patent/HUE043374T2/hu unknown
- 2014-09-29 RU RU2016111659A patent/RU2666352C2/ru not_active IP Right Cessation
- 2014-09-29 BR BR112016007078A patent/BR112016007078A2/pt not_active IP Right Cessation
- 2014-09-29 SG SG11201602477YA patent/SG11201602477YA/en unknown
- 2014-09-29 CA CA2925651A patent/CA2925651A1/en not_active Abandoned
- 2014-09-29 EP EP14847684.9A patent/EP3053916B1/en active Active
-
2016
- 2016-03-29 IL IL244813A patent/IL244813A0/en unknown
- 2016-03-29 PH PH12016500573A patent/PH12016500573A1/en unknown
- 2016-10-04 HK HK16111532.4A patent/HK1223356A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT3053916T (pt) | 2019-03-26 |
US20160311794A1 (en) | 2016-10-27 |
RU2016111659A3 (hu) | 2018-03-20 |
IL244813A0 (en) | 2016-05-31 |
CN105593221B (zh) | 2017-09-22 |
JP6380402B2 (ja) | 2018-08-29 |
SG11201602477YA (en) | 2016-05-30 |
HK1223356A1 (zh) | 2017-07-28 |
RU2016111659A (ru) | 2017-11-13 |
WO2015046482A1 (ja) | 2015-04-02 |
ES2716151T3 (es) | 2019-06-10 |
PH12016500573B1 (en) | 2016-07-04 |
EP3053916B1 (en) | 2019-01-30 |
BR112016007078A2 (pt) | 2017-12-12 |
DK3053916T3 (en) | 2019-04-15 |
RU2666352C2 (ru) | 2018-09-07 |
US9643951B2 (en) | 2017-05-09 |
TW201602092A (zh) | 2016-01-16 |
AU2014325078A1 (en) | 2016-04-21 |
EP3053916A1 (en) | 2016-08-10 |
CA2925651A1 (en) | 2015-04-02 |
KR20160062023A (ko) | 2016-06-01 |
MX2016004088A (es) | 2016-06-06 |
TWI628175B (zh) | 2018-07-01 |
PH12016500573A1 (en) | 2016-07-04 |
CN105593221A (zh) | 2016-05-18 |
PL3053916T3 (pl) | 2019-06-28 |
AU2014325078B2 (en) | 2018-10-25 |
JPWO2015046482A1 (ja) | 2017-03-09 |
EP3053916A4 (en) | 2017-03-08 |
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